Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   HPELS_RS00105 Genome accession   NC_017063
Coordinates   14349..16712 (+) Length   787 a.a.
NCBI ID   WP_000890273.1    Uniprot ID   -
Organism   Helicobacter pylori ELS37     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 9349..21712
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPELS_RS00070 (HPELS_00050) groES 9368..9724 (-) 357 WP_000671934.1 co-chaperone GroES -
  HPELS_RS00080 (HPELS_00055) dnaG 10011..11690 (+) 1680 WP_000601584.1 DNA primase -
  HPELS_RS00085 (HPELS_00060) - 11687..12739 (+) 1053 WP_000809433.1 MnmA/TRMU family protein -
  HPELS_RS00090 (HPELS_00065) - 12829..13656 (+) 828 WP_001154957.1 DUF5718 family protein -
  HPELS_RS00095 (HPELS_00070) comB2 13803..14084 (+) 282 WP_001272690.1 TrbC/VirB2 family protein Machinery gene
  HPELS_RS00100 (HPELS_00075) comB3 14084..14347 (+) 264 WP_000584956.1 hypothetical protein Machinery gene
  HPELS_RS00105 (HPELS_00080) comB4 14349..16712 (+) 2364 WP_000890273.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  HPELS_RS00110 (HPELS_00085) - 16924..18354 (+) 1431 WP_195182302.1 COG3014 family protein -
  HPELS_RS00115 (HPELS_00090) cheV1 18456..19421 (+) 966 WP_000785453.1 chemotaxis protein CheV1 -
  HPELS_RS00120 (HPELS_00095) nspC 19418..20635 (+) 1218 WP_000760859.1 carboxynorspermidine decarboxylase -
  HPELS_RS00125 (HPELS_00100) lpxE 20645..21217 (-) 573 WP_000713903.1 lipid A 1-phosphatase LpxE -

Sequence

Protein


Download         Length: 787 a.a.        Molecular weight: 90327.67 Da        Isoelectric Point: 8.0030

>NTDB_id=44661 HPELS_RS00105 WP_000890273.1 14349..16712(+) (comB4) [Helicobacter pylori ELS37]
MLEKFLGAIKQKVSNYFLGVLPKSYSMSEENNILGLYDEHFLLTKNENLVGILRLEGVSYTHLSTEQLQDLFTERQMALD
SLEKVVARLVVKRRKIDHQQNIQADSQYLQAILNQFENKEVYENQYFLVLESTHSLHGVLEHKKKSLMHANRENFKDILS
YKAHFLQETLKSLEIQLKNYAPKLLSSKEVLNFYAEYINGFDLPLKPLVGGYLSDSYIASSTTFEKDYFIQESFNQKTYN
RLIGIKAYESERITSIAVGALLYQETPLDIIFSIEPMSVHKTLSFLKERAKFSMSNLVKNELLEYQELVKTKRLSMQKFA
LNILIKAPNLENLDAQTSLVLGLLFKENLVGVIETFGLKGGYFSFFPERIHLNHRLRFLTSKALACLMVFERQNLGFKAN
SWGNSPLSVFKNLDYSPFLFNFHNQEVSHNNAKEIARVNGHTLVIGATGSGKSTLISFLMMSALKYQNMRLLAFDRMQGL
YSFTEFFKGHYHDGQSFSINPFCLEPNLQNLEFLQSFFLSMFDLAPSRDKEALEDMNAISSAIKSLYETLYPKDFSLLDF
KETLKRTSSNQLSLSLEPYLNNPLFNALNDAFNSNAFLNVINLDTITQNPKDLGLLAYYLFYKILEESRKNDSGFLVFLD
EFKSYVENDLLNTKINALITQARKANGVVVLALQDIYQLSGVKNAHSFLSNMGTLILYPQKNARELKHHFNVPLSETEIS
FLENTPLYARQVLVKNLGNGSSNMIDVSLESLGRYLKIFNSDSSHVNKVKALQKDYPTEWREKLLKS

Nucleotide


Download         Length: 2364 bp        

>NTDB_id=44661 HPELS_RS00105 WP_000890273.1 14349..16712(+) (comB4) [Helicobacter pylori ELS37]
ATGTTAGAAAAGTTTTTAGGCGCTATCAAACAAAAAGTTTCAAATTATTTTTTAGGGGTTTTGCCTAAAAGCTATTCTAT
GAGCGAAGAAAACAACATTTTAGGCTTGTATGATGAACATTTTTTACTCACTAAAAACGAAAACTTAGTGGGCATTCTCC
GTTTAGAGGGGGTGAGTTACACCCATTTAAGCACAGAGCAATTGCAAGATCTTTTCACCGAGCGCCAAATGGCGTTGGAT
TCTTTAGAAAAGGTCGTGGCGCGCCTGGTGGTTAAAAGGCGTAAAATTGATCACCAACAAAACATTCAAGCTGACTCTCA
ATACTTGCAAGCGATCTTGAATCAATTTGAAAATAAAGAAGTGTATGAGAATCAGTATTTTTTAGTTTTAGAAAGCACTC
ACTCTTTGCATGGCGTTTTAGAACATAAGAAAAAATCTCTCATGCATGCCAATAGGGAAAATTTTAAGGATATTCTCTCT
TATAAAGCGCATTTTTTGCAAGAAACTTTAAAAAGCCTAGAAATCCAGCTCAAAAATTATGCCCCCAAACTCTTAAGCTC
TAAAGAGGTTTTGAATTTTTATGCAGAATACATTAATGGGTTTGATCTCCCTTTAAAGCCCCTAGTAGGGGGGTATTTGA
GCGATAGCTATATCGCTAGTTCTACCACTTTTGAAAAAGATTATTTCATTCAAGAAAGCTTTAATCAAAAAACCTATAAC
CGCTTGATTGGCATTAAGGCTTATGAGAGCGAACGCATCACTTCTATAGCGGTGGGAGCGCTTTTATACCAAGAGACTCC
ACTAGATATTATCTTTTCCATAGAGCCTATGAGCGTGCATAAAACACTGAGTTTTTTAAAAGAGAGAGCCAAGTTTAGCA
TGTCTAATCTCGTTAAAAACGAGCTGTTAGAATACCAAGAATTAGTCAAAACCAAACGCCTATCCATGCAAAAATTCGCC
CTAAACATTCTTATCAAAGCCCCTAATTTAGAGAATTTAGACGCTCAAACTAGCTTAGTTTTAGGGCTTTTATTTAAAGA
AAATTTAGTGGGCGTTATAGAAACTTTTGGCTTGAAAGGGGGGTATTTTTCCTTTTTTCCTGAACGCATCCATTTAAACC
ACCGCTTGCGTTTTTTAACCTCTAAAGCCCTAGCGTGTTTAATGGTGTTTGAAAGGCAAAATTTAGGCTTTAAGGCTAAT
TCATGGGGGAATAGCCCTTTGAGCGTGTTTAAAAATTTGGATTATTCCCCTTTTTTATTCAATTTCCACAACCAAGAAGT
GAGCCACAATAACGCTAAAGAAATCGCCAGAGTGAATGGGCATACTTTAGTTATAGGGGCAACCGGAAGCGGTAAAAGCA
CGCTGATTAGCTTTTTAATGATGAGCGCTTTGAAATACCAAAACATGCGCCTTTTAGCCTTTGACAGGATGCAAGGGCTG
TATTCTTTCACCGAATTTTTTAAAGGGCATTACCATGATGGCCAATCTTTTAGCATCAACCCCTTTTGTTTAGAGCCTAA
TTTACAGAATTTAGAATTTTTGCAATCCTTCTTTTTGAGCATGTTTGATCTCGCCCCTTCAAGGGATAAAGAAGCCCTAG
AAGACATGAATGCGATTTCTAGCGCGATTAAGAGCCTTTATGAGACTTTATACCCTAAAGATTTTAGTTTGCTAGACTTT
AAAGAAACGCTTAAAAGAACTTCATCTAACCAACTAAGCTTGAGCTTGGAGCCGTATTTGAATAACCCCCTTTTTAACGC
TTTGAATGACGCATTCAATTCCAACGCTTTTTTAAATGTGATAAACCTAGACACCATCACCCAAAACCCTAAAGACTTAG
GGCTTTTAGCCTATTACTTGTTTTATAAAATTTTAGAAGAATCCAGGAAAAACGACAGCGGTTTTTTGGTTTTTTTAGAC
GAGTTTAAATCCTATGTGGAAAACGATTTATTGAACACCAAAATCAACGCTTTAATCACGCAAGCCAGAAAAGCTAATGG
CGTGGTGGTGTTGGCTTTGCAAGACATTTACCAATTAAGCGGGGTTAAAAACGCCCATAGTTTTTTAAGCAACATGGGGA
CTCTCATTTTGTACCCGCAAAAAAACGCTAGGGAGTTGAAACACCACTTCAATGTGCCTTTGAGCGAAACTGAAATTTCT
TTTTTAGAAAACACCCCTTTGTATGCCAGACAGGTTTTAGTCAAAAATTTGGGTAATGGGAGTTCTAACATGATTGATGT
GAGTTTGGAAAGCTTGGGGCGTTATTTGAAAATCTTTAATTCAGACTCTAGCCATGTCAATAAAGTGAAAGCGTTACAAA
AAGACTACCCTACAGAGTGGCGTGAGAAACTTTTGAAGAGCTAG

Domains

Predicted by InterproScan.

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(176-375)

FtsK/SpoIIIE family (FtsK_SpoIIIE)

(426-466)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

98.221

100

0.982

Multiple sequence alignment