Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   HPC60_RS12395 Genome accession   NZ_CP053671
Coordinates   2438482..2439492 (-) Length   336 a.a.
NCBI ID   WP_044009593.1    Uniprot ID   -
Organism   Lactococcus lactis subsp. lactis strain G121     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 2433482..2444492
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPC60_RS12375 (HPC60_07125) - 2434557..2435414 (-) 858 WP_023190258.1 Rgg/GadR/MutR family transcriptional regulator -
  HPC60_RS12380 (HPC60_07130) - 2435525..2436664 (-) 1140 WP_023190257.1 MFS transporter -
  HPC60_RS12385 (HPC60_07135) kwcM 2436661..2437980 (-) 1320 WP_058207975.1 KxxxW cyclic peptide radical SAM maturase -
  HPC60_RS12390 (HPC60_07140) - 2438048..2438161 (-) 114 WP_011836076.1 KxxxW-cyclized peptide pheromone -
  HPC60_RS12395 (HPC60_07145) sepM 2438482..2439492 (-) 1011 WP_044009593.1 SepM family pheromone-processing serine protease Regulator
  HPC60_RS12400 (HPC60_07150) coaD 2439496..2439993 (-) 498 WP_025017143.1 pantetheine-phosphate adenylyltransferase -
  HPC60_RS12405 (HPC60_07155) rsmD 2440041..2440580 (-) 540 WP_023190253.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  HPC60_RS12410 (HPC60_07160) - 2440751..2441971 (-) 1221 WP_190992191.1 MFS transporter -
  HPC60_RS12415 (HPC60_07165) lmrP 2442053..2443279 (-) 1227 WP_012898648.1 multidrug efflux MFS transporter LmrP -

Sequence

Protein


Download         Length: 336 a.a.        Molecular weight: 36556.95 Da        Isoelectric Point: 9.5171

>NTDB_id=446224 HPC60_RS12395 WP_044009593.1 2438482..2439492(-) (sepM) [Lactococcus lactis subsp. lactis strain G121]
MNPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSHFNSFTS
IYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAVNGQQFT
SSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSAGMMFTL
EIYSQLTGKDLRNGCEIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAKKLKTKMK
IVPVKTIQDALDYLEK

Nucleotide


Download         Length: 1011 bp        

>NTDB_id=446224 HPC60_RS12395 WP_044009593.1 2438482..2439492(-) (sepM) [Lactococcus lactis subsp. lactis strain G121]
ATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTTATTTTATCCAACGAGTTA
CTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGGAAAATGGTCAAAGTTGAAGGCAAAAAAGATGAACATAAAGGTG
ATTTTTTCCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCATTTTAATAGTTTTACAAGC
ATTTACAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCAGTTTTACATGGAAACGGC
ACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAACTTAAATATGAAGGCGTTTATGTCCTTG
ATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCAGTCAATGGTCAACAGTTTACA
TCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGAATACACGAGAATTGACGG
CACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGTAAAACAGGAATTGGGATTAGCCTAGTTGACCATA
CTGAAGTCGTGACGACTCCGAAAGTTACTGTCAACGCGGGTTCAATCGGTGGTCCCTCTGCGGGGATGATGTTTACACTA
GAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTTGCGAAATTGCTGGAACTGGGACGATTGAACACGACGG
AAGCATTGGTCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGTAAAGAAGGGGCAAAAGTCTTCTTAGTGCCTG
ATTCAGGCACCAAAAAGGAAAGTAGCAACAATTACCTTGGAGCCAAAGCCGCCGCTAAAAAACTAAAAACGAAGATGAAA
ATCGTTCCCGTCAAAACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(221-332)

PDZ domain (PDZ_2)

(128-188)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

48.397

100

0.494