Detailed information NTG0446188

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: HPC60_RS03350
• Genome accession: NZ_CP053671
• Coordinates: 632300..634750 (+)
• Length: 816 a.a.
• NCBI ID: WP_179107876.1
• Uniprot ID: -
• Organism: Lactococcus lactis subsp. lactis strain G121
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 627300..639750

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HPC60_RS03325 (HPC60_11205)	-	628064..628576 (+)	513	WP_012897343.1	adenine phosphoribosyltransferase	-
HPC60_RS03330 (HPC60_11210)	rpoE	628793..629356 (+)	564	WP_012897344.1	DNA-directed RNA polymerase subunit delta	-
HPC60_RS03335 (HPC60_11215)	mltG	629493..631145 (+)	1653	WP_179107875.1	endolytic transglycosylase MltG	-
HPC60_RS03340 (HPC60_11220)	greA	631205..631678 (+)	474	WP_025016857.1	transcription elongation factor GreA	-
HPC60_RS03345 (HPC60_11225)	-	631855..632310 (+)	456	WP_010905471.1	CtsR family transcriptional regulator	-
HPC60_RS03350 (HPC60_11230)	clpC	632300..634750 (+)	2451	WP_179107876.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
HPC60_RS03355 (HPC60_11235)	hpf	634885..635442 (+)	558	WP_003129564.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
HPC60_RS03360 (HPC60_11240)	eno	635627..636928 (+)	1302	WP_010905473.1	surface-displayed alpha-enolase	-
HPC60_RS03365 (HPC60_11245)	-	637043..637714 (-)	672	WP_010905491.1	ABC transporter ATP-binding protein	-
HPC60_RS03370 (HPC60_11250)	-	637717..638790 (-)	1074	WP_003129569.1	ABC transporter permease	-
HPC60_RS03375 (HPC60_11255)	-	638802..639371 (-)	570	WP_023188929.1	TetR/AcrR family transcriptional regulator	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90425.78 Da
• Isoelectric Point: 6.4339

>NTDB_id=446188 HPC60_RS03350 WP_179107876.1 632300..634750(+) (clpC) [Lactococcus lactis subsp. lactis strain G121]
MKFENIKYTPTLDRILEKAEEYAHQYQYGTIESAHLLAAMATTSGSIAYSLLAGMNVDSSDLLIDLEDLSSHVKVKRSTL
RFSPRAEEVMTAASFLAIHNNSEAVGTEHLLYALLQVEDGFGLQLLKLQKINIVSLRKELEKRTGLKVPESKKAVTPMSK
RKMAKGVAENSTTPTLDSVSSDLTEEARLGKLDPMIGREAEIDRLIHILSRRTKNNPVLVGEPGVGKSAIIEGLAQRIVN
GQVPIGLMNSRIMALNMATVVAGTKFRGEFEDRLTAIVEEVSSDPDVIIFIDELHTIIGAGGGMDSVNDAANILKPALAR
GDFQMVGATTYHEYQKYIEKDEALERRLARINVDEPSPDEAIAILQGLREKFEDYHQVEFTDQAIKSAVMLSVRYMTSRK
LPDKAIDLLDEAAAAVKISVKNQQTKRLDLEKELAEAQEELSEAVIKLDIKASRTKEKAVEKIADKIYKFSVKEDKRQEV
TDQAVVAVASTLTGVPITQMTKSESDRLINLEKELHKRVVGQEEAISAVSRAIRRARSGVADSRRPMGSFMFLGPTGVGK
TELAKALADSVFGSEDNMIRVDMSEFMEKHSTSRLIGAPPGYVGYDEGGQLTERVRNKPYSVVLLDEVEKAHPDVFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATALRDDKTVGFGAKNITADYSAMKSRILEELKRHYRPEFLNRIDENIVF
HSLESQEIEQIVKIMSKSLIKRLAEQNIHVKLTPSAVKLIAEVGFDPEYGARPLRKALQKEVEDLLSEQLLSGEIKAGNH
VSIGASNKKIKIAQIV

Nucleotide

• Length: 2451 bp

>NTDB_id=446188 HPC60_RS03350 WP_179107876.1 632300..634750(+) (clpC) [Lactococcus lactis subsp. lactis strain G121]
ATGAAATTTGAAAATATAAAATATACACCAACGCTTGACCGAATTTTAGAAAAAGCGGAAGAGTATGCTCACCAATATCA
ATATGGCACCATTGAAAGTGCTCATTTACTAGCTGCAATGGCAACGACCTCAGGCTCAATTGCTTACAGCCTTCTTGCAG
GAATGAATGTTGATTCTTCTGACTTACTGATTGATTTAGAGGATTTATCAAGTCATGTTAAGGTCAAACGTTCAACTTTA
CGTTTTTCACCTCGTGCAGAAGAAGTGATGACTGCGGCAAGTTTTTTAGCAATTCATAATAACTCAGAAGCCGTTGGAAC
AGAACACTTGCTTTATGCCCTACTTCAAGTAGAAGATGGATTTGGTCTTCAACTTCTGAAATTACAAAAAATCAATATTG
TATCTTTGCGAAAAGAGCTTGAGAAAAGAACTGGACTCAAAGTTCCAGAAAGTAAAAAAGCTGTGACTCCAATGTCAAAA
CGTAAGATGGCAAAGGGAGTTGCAGAAAATTCAACGACGCCAACGTTAGACTCTGTATCCTCAGATTTAACCGAAGAAGC
TCGCTTGGGTAAACTTGACCCAATGATTGGACGAGAAGCTGAAATTGACCGTTTGATTCATATTCTCAGCCGCAGAACAA
AAAATAATCCTGTCTTAGTTGGAGAGCCCGGTGTTGGGAAATCAGCAATTATTGAAGGTTTGGCTCAAAGAATTGTCAAT
GGTCAAGTTCCAATTGGTTTGATGAATAGTCGAATTATGGCCTTGAATATGGCGACTGTTGTTGCTGGGACAAAATTTAG
AGGTGAATTTGAGGATCGTTTGACAGCAATTGTTGAAGAAGTTAGCAGTGATCCAGATGTCATTATTTTCATTGATGAAT
TACACACAATCATCGGTGCTGGTGGCGGTATGGATTCTGTCAATGATGCCGCAAATATTTTGAAACCAGCGCTTGCTCGT
GGTGATTTTCAAATGGTCGGAGCAACAACCTATCATGAATATCAAAAATATATTGAAAAAGATGAAGCTTTAGAACGCCG
TTTGGCGAGAATAAATGTTGACGAGCCAAGTCCAGATGAAGCGATTGCTATCTTGCAAGGCTTACGTGAAAAATTTGAAG
ACTATCATCAAGTGGAATTTACTGACCAAGCCATTAAAAGTGCTGTAATGCTCAGTGTCCGTTATATGACTAGCCGAAAA
TTGCCTGACAAAGCCATTGATTTACTTGATGAAGCTGCAGCAGCAGTGAAAATTTCTGTCAAAAATCAACAAACAAAACG
TCTTGATTTAGAAAAAGAATTAGCGGAAGCTCAAGAAGAATTATCAGAAGCTGTCATTAAACTTGATATCAAAGCGTCTC
GTACAAAAGAAAAAGCAGTTGAAAAAATTGCTGACAAGATTTATAAATTCTCAGTAAAAGAAGATAAACGTCAAGAAGTT
ACTGACCAAGCTGTTGTTGCTGTTGCCTCAACACTGACAGGTGTTCCAATCACACAAATGACTAAGTCTGAAAGTGATCG
TTTAATCAATCTTGAAAAAGAATTACACAAACGAGTTGTTGGACAAGAAGAAGCTATTTCTGCCGTTTCAAGAGCCATTC
GTCGGGCACGTTCCGGTGTTGCTGACAGCCGTCGTCCAATGGGTTCTTTCATGTTCCTTGGACCAACAGGGGTCGGTAAA
ACCGAACTTGCTAAAGCACTGGCTGACAGTGTGTTTGGTAGTGAAGATAATATGATTCGTGTTGACATGAGTGAATTCAT
GGAAAAACATTCGACTTCACGCTTGATTGGAGCTCCTCCAGGGTATGTAGGTTATGATGAGGGTGGTCAATTGACAGAAC
GCGTTCGTAATAAACCTTATTCTGTTGTTCTTTTAGATGAAGTCGAAAAAGCTCATCCTGACGTTTTCAACATCATGTTG
CAAATTCTAGATGATGGCTTTGTGACTGATACTAAAGGTCGTAAAGTTGATTTCAGAAATACAATTATTATCATGACTTC
AAACTTGGGAGCGACTGCTCTTCGTGATGATAAGACAGTTGGTTTTGGCGCTAAAAATATCACAGCTGATTATTCAGCCA
TGAAATCAAGAATATTAGAAGAGCTTAAACGTCATTATCGTCCTGAGTTTCTTAATCGAATTGATGAAAATATTGTTTTC
CACTCATTGGAAAGTCAAGAGATTGAACAAATTGTTAAAATTATGAGTAAATCTTTGATTAAACGTCTGGCAGAACAAAA
TATTCATGTTAAACTCACACCGTCAGCGGTGAAATTAATTGCTGAGGTAGGTTTTGACCCAGAATATGGTGCACGTCCGC
TCCGCAAGGCTCTTCAAAAAGAAGTTGAAGACCTTTTAAGTGAACAATTGCTCTCTGGTGAAATCAAAGCAGGTAATCAT
GTTTCAATTGGGGCATCTAATAAAAAAATTAAAATCGCTCAAATTGTTTGA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (357-453)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-802)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (19-69)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (96-144)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

• ATPase family associated with various cellular activities (AAA) (AAA) (218-334)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	99.755	100	0.998
clpC	Streptococcus thermophilus LMD-9	50.542	100	0.515
clpC	Streptococcus thermophilus LMG 18311	50.421	100	0.513
clpC	Streptococcus pneumoniae Rx1	48.798	100	0.498
clpC	Streptococcus pneumoniae D39	48.798	100	0.498
clpC	Streptococcus pneumoniae TIGR4	48.678	100	0.496
clpC	Streptococcus mutans UA159	48.558	100	0.495
clpC	Bacillus subtilis subsp. subtilis str. 168	50.374	98.284	0.495
clpE	Streptococcus mutans UA159	47.692	79.657	0.38
clpC	Lactococcus lactis subsp. cremoris KW2	46.718	80.27	0.375
clpE	Streptococcus pneumoniae R6	47.847	76.838	0.368
clpE	Streptococcus pneumoniae Rx1	47.847	76.838	0.368
clpE	Streptococcus pneumoniae TIGR4	47.847	76.838	0.368
clpE	Streptococcus pneumoniae D39	47.847	76.838	0.368