Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   HPC60_RS02905 Genome accession   NZ_CP053671
Coordinates   550544..552790 (+) Length   748 a.a.
NCBI ID   WP_012897283.1    Uniprot ID   A0A3N6H9U1
Organism   Lactococcus lactis subsp. lactis strain G121     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 545544..557790
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPC60_RS02885 (HPC60_10765) rpoD 546158..547480 (+) 1323 WP_169743964.1 RNA polymerase sigma factor RpoD -
  HPC60_RS02890 (HPC60_10770) - 547595..548338 (+) 744 WP_010905438.1 MurR/RpiR family transcriptional regulator -
  HPC60_RS02895 (HPC60_10775) - 548503..549870 (+) 1368 Protein_551 MFS transporter -
  HPC60_RS02900 (HPC60_10780) - 550155..550493 (+) 339 WP_021723450.1 hypothetical protein -
  HPC60_RS02905 (HPC60_10785) clpC 550544..552790 (+) 2247 WP_012897283.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  HPC60_RS02910 (HPC60_10790) - 553073..553543 (-) 471 WP_003130820.1 Rrf2 family transcriptional regulator -
  HPC60_RS02915 (HPC60_10795) gap 553716..554729 (+) 1014 WP_023189445.1 type I glyceraldehyde-3-phosphate dehydrogenase -
  HPC60_RS02920 (HPC60_10800) def 554872..555507 (-) 636 WP_003130816.1 peptide deformylase -
  HPC60_RS02925 (HPC60_10805) - 555655..556116 (+) 462 WP_306171264.1 RNA pyrophosphohydrolase -

Sequence

Protein


Download         Length: 748 a.a.        Molecular weight: 83114.84 Da        Isoelectric Point: 4.7623

>NTDB_id=446187 HPC60_RS02905 WP_012897283.1 550544..552790(+) (clpC) [Lactococcus lactis subsp. lactis strain G121]
MLCQNCNINEATIHLYTSVNGQKKQIDLCQNCYQIMKSGGQEALFGAGNASNGNSDEPFNPFNDIFSALHGQDFNGAAST
QTPPTQTGGRGPRGPQNPRAKQPKGMLEEFGINITESARRGEIDPVIGRDEEIKRVIEILNRRTKNNPVLIGEPGVGKTA
VVEGLAQKIVDGDVPQKLQNKEVIRLDVVSLVQGTGIRGQFEERMQKLMDEIRKRNDVIMFIDEIHEIVGAGSAGDGNMD
AGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVDETITILRGIQARYEDYHHVKYTDEAIEAAAH
LSNRYIQDRFLPDKAIDLLDESGSKKNLTLKFVDPEDINRRIADAETKKNEATQAEDFEKAAHFRDQITKLRELQNHEVS
DDEIPVITEKDIEQIVEQKTHIPVGDLKEKEQTQLINLADDLKAHVIGQDEAVDKIAKAIRRSRVGLGKPNRPIGSFLFV
GPTGVGKTELAKQLAKELFGSSESMIRFDMSEYMEKHSVAKLIGAPPGYVGYEEAGQLTERVRRNPYSLILLDEIEKAHP
DVMHMFLQILEDGRLTDAQGRTVSFKDSLIIMTSNAGTGKVEASVGFGAAREGRTKSVLGQLGDFFSPEFMNRFDGIIEF
SALSKENLLKIVDLMLDEVNEQIGRNDIHLSVTQAAKEKLVDLGYNPAMGARPLRRTIQENIEDSIADFYIEHPEYKELV
ADLIDDKIVISNQAQEAAETTDEEVPAE

Nucleotide


Download         Length: 2247 bp        

>NTDB_id=446187 HPC60_RS02905 WP_012897283.1 550544..552790(+) (clpC) [Lactococcus lactis subsp. lactis strain G121]
ATGCTTTGTCAAAATTGTAATATTAATGAAGCGACGATTCACCTTTACACAAGTGTAAATGGTCAGAAAAAACAAATTGA
TTTGTGCCAAAACTGTTATCAAATTATGAAATCTGGCGGTCAAGAAGCTTTATTTGGCGCAGGAAATGCCTCAAATGGAA
ATTCTGATGAACCATTTAATCCATTTAATGATATCTTTAGTGCTTTGCACGGTCAAGATTTTAATGGAGCAGCAAGCACT
CAAACTCCACCAACACAAACAGGTGGACGTGGTCCGCGCGGTCCACAAAATCCTCGGGCAAAACAACCTAAAGGAATGTT
AGAAGAATTTGGAATTAACATCACAGAGTCAGCTCGTCGTGGCGAAATTGACCCAGTGATTGGGCGTGATGAAGAAATTA
AACGTGTCATTGAGATTTTAAATCGTAGGACTAAGAATAATCCTGTATTAATTGGTGAACCTGGTGTTGGTAAAACAGCA
GTTGTTGAAGGTTTAGCGCAAAAAATTGTGGACGGAGATGTGCCGCAAAAACTACAAAATAAAGAAGTGATTCGTCTTGA
TGTTGTTTCTCTTGTTCAAGGAACAGGAATTCGTGGACAATTTGAAGAACGGATGCAAAAATTAATGGATGAAATCAGAA
AACGTAATGATGTGATTATGTTTATTGATGAAATTCATGAAATTGTTGGTGCTGGTTCTGCCGGTGATGGCAATATGGAT
GCAGGAAATATCCTAAAACCTGCGCTTGCGCGTGGTGAGCTTCAATTGGTCGGAGCAACAACGCTCAATGAATATCGCAT
CATTGAAAAAGATGCTGCGCTTGAACGCCGGATGCAACCAGTTAAAGTCGATGAACCATCAGTTGATGAAACAATTACTA
TTTTGCGAGGCATTCAAGCACGTTATGAAGATTATCATCACGTGAAATACACTGATGAGGCTATTGAAGCAGCCGCTCAT
TTGTCAAATCGTTACATTCAAGACCGTTTCTTACCAGATAAAGCCATTGACCTTTTGGATGAGTCTGGTTCTAAGAAAAA
TCTAACCTTGAAATTTGTTGATCCTGAAGATATTAATCGTCGGATTGCGGATGCAGAAACGAAGAAAAATGAAGCAACAC
AGGCTGAAGATTTTGAAAAAGCCGCTCATTTCCGTGACCAAATCACTAAACTTCGTGAATTACAAAATCATGAAGTTTCA
GATGATGAAATTCCTGTCATCACTGAAAAAGATATTGAACAAATTGTTGAGCAAAAAACACATATTCCAGTTGGTGATTT
GAAAGAAAAAGAACAAACCCAATTGATTAATTTGGCTGATGATTTGAAAGCACATGTGATTGGTCAGGATGAAGCAGTGG
ATAAGATTGCTAAAGCTATCCGTCGTTCTCGTGTGGGACTTGGTAAACCTAATCGTCCAATTGGTTCTTTCCTTTTCGTT
GGTCCAACAGGTGTTGGTAAAACAGAACTTGCTAAACAATTGGCTAAAGAATTATTTGGCTCAAGTGAAAGTATGATTCG
TTTTGACATGTCGGAATACATGGAAAAACATTCGGTGGCCAAATTGATTGGAGCCCCTCCAGGATATGTGGGTTATGAAG
AAGCTGGTCAATTGACTGAACGTGTTCGTCGTAATCCCTACAGTTTGATTTTATTAGATGAAATCGAAAAAGCACATCCA
GATGTGATGCACATGTTCTTGCAAATTCTTGAAGATGGACGTCTGACAGACGCACAAGGACGGACAGTATCCTTTAAAGA
TAGTTTGATTATTATGACTTCTAATGCCGGAACTGGTAAAGTTGAAGCCTCTGTCGGATTTGGTGCTGCTCGTGAGGGAC
GAACTAAATCAGTGCTTGGTCAGCTTGGCGATTTCTTTAGCCCCGAATTCATGAACCGTTTTGACGGAATTATTGAATTC
TCTGCTTTGAGCAAAGAAAATCTCCTTAAAATTGTTGATTTGATGCTTGATGAAGTCAACGAACAAATTGGACGTAATGA
TATTCATCTTAGTGTCACTCAAGCAGCAAAAGAAAAATTAGTTGATCTAGGTTACAATCCAGCAATGGGTGCAAGACCAC
TTCGTAGAACAATTCAAGAAAATATCGAAGATTCAATTGCTGACTTCTATATTGAACACCCTGAATACAAAGAATTGGTT
GCTGATTTGATTGATGATAAAATTGTTATCTCTAATCAAGCTCAAGAAGCAGCAGAAACGACTGATGAAGAAGTTCCTGC
TGAATAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(472-635)

AAA lid domain (AAA_lid_9)

(287-386)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(643-713)

ATPase family associated with various cellular activities (AAA) (AAA)

(149-268)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3N6H9U1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. cremoris KW2

97.861

100

0.979
  clpE Streptococcus mutans UA159

76.026

100

0.767
  clpE Streptococcus pneumoniae Rx1

75.543

98.396

0.743
  clpE Streptococcus pneumoniae D39

75.543

98.396

0.743
  clpE Streptococcus pneumoniae R6

75.543

98.396

0.743
  clpE Streptococcus pneumoniae TIGR4

75.543

98.396

0.743
  clpC Bacillus subtilis subsp. subtilis str. 168

51.672

87.968

0.455
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

47.635

81.952

0.39
  clpC Streptococcus pneumoniae Rx1

46.635

83.422

0.389
  clpC Streptococcus pneumoniae D39

46.635

83.422

0.389
  clpC Streptococcus pneumoniae TIGR4

46.635

83.422

0.389
  clpC Streptococcus thermophilus LMD-9

46.104

82.353

0.38
  clpC Streptococcus thermophilus LMG 18311

45.942

82.353

0.378
  clpC Streptococcus mutans UA159

45.631

82.62

0.377