Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   I5043_RS04320 Genome accession   NZ_CP065353
Coordinates   920072..921880 (+) Length   602 a.a.
NCBI ID   WP_000082725.1    Uniprot ID   A0A2K4AK92
Organism   Staphylococcus aureus strain AR39_O1_merpol     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 915072..926880
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I5043_RS04295 (I5043_04295) opp4C 915225..916106 (+) 882 WP_001180264.1 oligopeptide ABC transporter permease -
  I5043_RS04300 (I5043_04300) trpS 916148..917137 (-) 990 WP_000448934.1 tryptophan--tRNA ligase -
  I5043_RS04305 (I5043_04305) spxA 917432..917827 (+) 396 WP_000258003.1 transcriptional regulator SpxA -
  I5043_RS04310 (I5043_04310) mecA 918198..918917 (+) 720 WP_001217736.1 adaptor protein MecA -
  I5043_RS04315 (I5043_04315) coiA 919038..920024 (+) 987 WP_000959280.1 competence protein CoiA Machinery gene
  I5043_RS04320 (I5043_04320) pepF 920072..921880 (+) 1809 WP_000082725.1 oligoendopeptidase F Regulator
  I5043_RS04325 (I5043_04325) yjbH 922340..923146 (-) 807 WP_000896697.1 protease adaptor protein YjbH -
  I5043_RS04330 (I5043_04330) - 923169..923534 (-) 366 WP_000214067.1 truncated hemoglobin YjbI -
  I5043_RS04335 (I5043_04335) - 923638..924231 (-) 594 WP_000224616.1 CYTH domain-containing protein -
  I5043_RS04340 (I5043_04340) - 924417..924764 (+) 348 WP_001242107.1 hypothetical protein -
  I5043_RS04345 (I5043_04345) - 924781..925416 (+) 636 WP_001077683.1 GTP pyrophosphokinase -
  I5043_RS04350 (I5043_04350) - 925433..926242 (+) 810 WP_001270834.1 NAD kinase -

Sequence

Protein


Download         Length: 602 a.a.        Molecular weight: 69805.37 Da        Isoelectric Point: 4.9226

>NTDB_id=446159 I5043_RS04320 WP_000082725.1 920072..921880(+) (pepF) [Staphylococcus aureus strain AR39_O1_merpol]
MSQQLSREEQERKYPEYTWDLTTIFKDDEAFEAAFKEVENELGKEEQFKGHIGDSAETLYNALELEDTLGTKLEKVYVYA
HLKQDQDTTNDKYTGMESRAHQLIIKFSSAWSFLVPEILQIDEDKIQSFVNSYDKLQKFAFDLKLINEKRPHILDAETEK
LLTEAQDALSTPSNVYGMFSNADLVFEDAIDKDGNAHPLTQGTFIKYLESDDRKLRESAFRNVYKAYGAHNNTLGATLAG
EVKKNVFNARTHNYKTAREKALSNNHIPENVYDNLVKTVHKYLPLLHRYTELRKELLGLDDLKMYDLYTPLIKDIKFEMP
YEEAKEWMLKALEPMGEEYLNVVKEGLNNRWVDVYENKGKRSGGYSSGAHLTNPFILLNWSNTISDLYTLVHEFGHSAHS
YFSRKFQPSNSSDYTIFVAEVASTCNEALLSDYMDKHLDDEKRLLLLNQELERFRATLFRQTMFAEFEHKIHAIEEAGEP
LTPTRMNEEYAKLNKLYFGDSVETDEDISKEWSRIPHFYMNYYVYQYATGYSAAQSLSHQILTEGKPAVDRYINEFLKKG
SSNYPIEILKNAGVDMTTPEPIEQACEVFEQKLNAFEKLMKA

Nucleotide


Download         Length: 1809 bp        

>NTDB_id=446159 I5043_RS04320 WP_000082725.1 920072..921880(+) (pepF) [Staphylococcus aureus strain AR39_O1_merpol]
ATGAGTCAACAATTATCGAGAGAAGAACAGGAACGTAAATATCCTGAATATACATGGGACTTAACAACAATTTTTAAAGA
TGATGAAGCTTTTGAGGCTGCATTTAAAGAAGTTGAAAATGAGTTAGGCAAAGAAGAACAATTTAAAGGACACATTGGTG
ATAGTGCTGAGACATTATACAATGCGTTAGAATTAGAAGATACATTAGGTACTAAATTAGAAAAAGTATATGTATACGCG
CACCTAAAACAAGACCAAGATACAACGAACGACAAGTATACTGGTATGGAGTCAAGAGCACATCAATTAATTATTAAATT
TAGCTCGGCGTGGAGTTTCTTAGTGCCAGAGATTTTACAAATTGATGAAGATAAAATTCAATCATTTGTAAATTCATATG
ATAAATTACAAAAATTCGCATTTGATTTGAAGTTGATTAACGAAAAACGTCCTCATATTTTAGATGCTGAAACTGAAAAG
TTATTAACAGAAGCGCAGGACGCGTTATCAACACCATCAAATGTATACGGTATGTTTAGCAACGCTGATTTAGTATTTGA
AGATGCGATTGATAAAGATGGAAATGCACACCCGTTAACACAAGGTACATTTATTAAGTATTTAGAATCAGATGATCGCA
AACTAAGAGAGAGTGCTTTTAGAAATGTATATAAAGCATATGGTGCTCATAATAATACGCTTGGCGCTACGCTAGCAGGT
GAAGTGAAGAAAAATGTATTTAATGCTCGTACACACAATTACAAAACTGCAAGAGAAAAAGCATTGAGTAATAATCATAT
TCCAGAAAATGTATATGACAATCTAGTAAAAACTGTACATAAATATTTACCATTGCTACATAGATATACTGAATTGCGCA
AAGAATTGCTAGGTTTAGATGACTTGAAAATGTATGATTTATATACACCATTAATTAAAGATATTAAGTTTGAAATGCCT
TATGAAGAAGCTAAAGAGTGGATGTTAAAAGCTTTAGAACCAATGGGTGAAGAATATTTAAATGTAGTTAAAGAAGGCTT
AAACAATCGTTGGGTCGATGTCTATGAGAATAAAGGTAAACGTTCAGGTGGCTATTCATCAGGTGCACATTTAACTAATC
CATTTATTCTACTTAACTGGTCTAATACTATTTCAGACTTATACACATTAGTTCATGAATTTGGACATTCAGCACATAGT
TACTTCAGTAGAAAATTCCAACCGTCAAATTCTAGTGACTACACTATTTTTGTCGCTGAAGTAGCATCAACTTGTAACGA
AGCACTTTTAAGTGATTATATGGATAAACATCTTGATGATGAAAAACGCTTATTATTATTAAACCAAGAATTAGAACGTT
TCAGAGCTACATTATTCCGACAAACAATGTTCGCAGAATTTGAGCATAAAATTCATGCAATTGAAGAAGCAGGTGAACCA
TTAACGCCAACTAGAATGAATGAAGAATATGCCAAATTAAATAAATTATACTTCGGTGATTCTGTAGAAACTGATGAAGA
TATTAGTAAGGAATGGTCACGAATTCCACACTTCTATATGAATTATTATGTATATCAATACGCAACTGGTTACAGTGCAG
CTCAAAGCTTAAGTCATCAAATTTTAACAGAAGGTAAGCCAGCAGTAGATAGATATATTAATGAATTCTTGAAAAAAGGT
AGCTCAAATTATCCAATTGAGATATTAAAAAATGCTGGTGTAGATATGACAACACCTGAACCAATTGAACAAGCTTGTGA
AGTTTTTGAACAAAAATTGAACGCTTTTGAAAAATTAATGAAAGCTTAG

Domains

Predicted by InterProScan.

Peptidase family M3 (Peptidase_M3)

(207-587)

Oligopeptidase F (Peptidase_M3_N)

(117-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2K4AK92

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

43.952

97.508

0.429