Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   I3K83_RS04700 Genome accession   NZ_CP065199
Coordinates   978400..979119 (+) Length   239 a.a.
NCBI ID   WP_001217723.1    Uniprot ID   -
Organism   Staphylococcus aureus strain DG36     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 973400..984119
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I3K83_RS04675 (I3K83_04675) - 973481..974460 (+) 980 Protein_916 ABC transporter ATP-binding protein -
  I3K83_RS04680 (I3K83_04680) opp4B 974453..975415 (+) 963 WP_000239820.1 oligopeptide ABC transporter permease -
  I3K83_RS04685 (I3K83_04685) opp4C 975427..976308 (+) 882 WP_001180280.1 oligopeptide ABC transporter permease -
  I3K83_RS04690 (I3K83_04690) trpS 976350..977339 (-) 990 WP_031589556.1 tryptophan--tRNA ligase -
  I3K83_RS04695 (I3K83_04695) spxA 977634..978029 (+) 396 WP_000258003.1 transcriptional regulator SpxA -
  I3K83_RS04700 (I3K83_04700) mecA 978400..979119 (+) 720 WP_001217723.1 adaptor protein MecA Regulator
  I3K83_RS04705 (I3K83_04705) coiA 979240..980226 (+) 987 WP_000959292.1 competence protein CoiA Machinery gene
  I3K83_RS04710 (I3K83_04710) pepF 980274..982082 (+) 1809 WP_000082725.1 oligoendopeptidase F Regulator
  I3K83_RS04715 (I3K83_04715) yjbH 982542..983348 (-) 807 WP_000896697.1 protease adaptor protein YjbH -
  I3K83_RS04720 (I3K83_04720) - 983371..983736 (-) 366 WP_031775447.1 truncated hemoglobin YjbI -

Sequence

Protein


Download         Length: 239 a.a.        Molecular weight: 28285.17 Da        Isoelectric Point: 4.1548

>NTDB_id=445988 I3K83_RS04700 WP_001217723.1 978400..979119(+) (mecA) [Staphylococcus aureus strain DG36]
MRIERVDDTTVKLFITYSDIEARGFSREDLWTNRKRGEEFFWSMMDEINEEEDFVVEGPLWIQVHAFEKGVEVTISKSKN
EDMMNMSDDDATDQFDEQVQELLAQTLEGEDQLEELFDQRTKEKEAQGSKRQKSSARKNTRTIIVKFNDLEDVINYAYHS
NPITTEFEDLLYMVDGTYYYAVHFDSHVDQEVINDSYSQLLEFAYPTDRTEVYLNDYAKIIMSHNVTAQVRRYFPETTE

Nucleotide


Download         Length: 720 bp        

>NTDB_id=445988 I3K83_RS04700 WP_001217723.1 978400..979119(+) (mecA) [Staphylococcus aureus strain DG36]
ATGAGAATAGAACGAGTAGATGATACAACTGTAAAATTGTTTATAACATATAGCGATATCGAGGCCCGTGGATTTAGTCG
TGAAGATTTATGGACAAATCGCAAACGTGGCGAAGAATTCTTTTGGTCAATGATGGATGAAATTAACGAAGAAGAAGATT
TTGTTGTAGAAGGTCCATTATGGATTCAAGTACATGCCTTTGAAAAAGGTGTCGAAGTCACAATTTCTAAATCTAAAAAT
GAAGATATGATGAATATGTCTGATGATGATGCAACTGATCAATTTGATGAACAAGTTCAAGAATTGTTAGCTCAAACATT
AGAAGGTGAAGATCAATTAGAAGAATTATTCGATCAACGAACAAAAGAAAAAGAAGCTCAAGGTTCTAAACGTCAAAAGT
CTTCAGCACGTAAAAATACAAGAACAATTATTGTGAAATTTAACGATTTAGAAGATGTTATTAATTATGCATATCATAGC
AATCCAATAACTACAGAGTTTGAAGATTTGTTATATATGGTTGATGGTACTTATTATTATGCTGTACATTTTGATAGTCA
TGTTGATCAAGAAGTCATTAATGATAGTTACAGTCAATTGCTTGAATTTGCTTATCCAACAGACAGAACAGAAGTTTATT
TAAATGACTATGCTAAAATAATTATGAGTCATAACGTAACAGCTCAAGTTCGACGTTATTTTCCAGAGACAACTGAATAA

Domains

Predicted by InterProScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

37.975

99.163

0.377