Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   HA036_RS04115 Genome accession   NZ_CP053639
Coordinates   787969..789318 (-) Length   449 a.a.
NCBI ID   WP_031806890.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 14732     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 779555..794597 787969..789318 within 0


Gene organization within MGE regions


Location: 779555..794597
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HA036_RS04075 (HA036_04085) mecA 779555..781564 (-) 2010 WP_001801873.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -
  HA036_RS04080 (HA036_04090) - 781661..782647 (+) 987 WP_001549960.1 beta-lactam sensor/signal transducer MecR1 -
  HA036_RS04085 (HA036_04095) - 782637..782878 (+) 242 Protein_765 type I restriction enzyme endonuclease domain-containing protein -
  HA036_RS04090 (HA036_04100) - 782869..784476 (-) 1608 Protein_766 IS1182 family transposase -
  HA036_RS04095 (HA036_04105) - 784528..785034 (-) 507 WP_001092189.1 DUF1643 domain-containing protein -
  HA036_RS04100 (HA036_04110) - 785049..785360 (-) 312 WP_000700851.1 DUF960 family protein -
  HA036_RS04105 (HA036_04115) - 785447..785797 (-) 351 WP_000849672.1 SAUGI family uracil-DNA glycosylase inhibitor -
  HA036_RS04110 (HA036_04120) ccrB 786319..787947 (-) 1629 WP_001186608.1 cassette chromosome recombinase CcrB Machinery gene
  HA036_RS04115 (HA036_04125) ccrA 787969..789318 (-) 1350 WP_031806890.1 cassette chromosome recombinase CcrA Machinery gene
  HA036_RS04120 (HA036_04130) - 789552..791345 (-) 1794 WP_031806891.1 cassette chromosome replicative helicase -
  HA036_RS04125 (HA036_04135) - 791345..791638 (-) 294 WP_001587828.1 cassette chromosome ssDNA-binding protein -
  HA036_RS04130 (HA036_04140) - 791873..793012 (+) 1140 Protein_774 IS3 family transposase -
  HA036_RS04135 (HA036_04145) - 793083..794597 (-) 1515 WP_001587831.1 hypothetical protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52629.19 Da        Isoelectric Point: 9.9252

>NTDB_id=445862 HA036_RS04115 WP_031806890.1 787969..789318(-) (ccrA) [Staphylococcus aureus strain 14732]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQITQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRLKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYEYH
NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRLQKQTKQTSSDNQLKQKINCPCCNATLTNMTVRKKNHILRYYVCPKNMNASRFVCDFKGINAQTFEDKVLEV
CRDFYQNQRIYTKIKGAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQHTIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQTMQSSIA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=445862 HA036_RS04115 WP_031806890.1 787969..789318(-) (ccrA) [Staphylococcus aureus strain 14732]
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGTCGCAAAGATAATCGTAGTGGGT
ATCGACAAATAACACAATTAATTCAACAAGGACAGTGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
CTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACGTACCATGTTCATATCTTAAGCGTACATGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGACTCAAGCTTAATATCTTCATCAGTTTAGCCGAACTTGAATCGGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACACATGCACCTTTTGGTTACGAATATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGCCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATTGCAAAAACAAACCAAACAGACATCTTCGGATAATCAACTCAAACAAAAAATCAA
TTGCCCATGTTGTAATGCAACACTTACAAATATGACCGTTAGAAAAAAGAATCATATATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCACGCTTTGTATGTGATTTCAAAGGCATCAATGCACAAACATTTGAAGATAAAGTATTAGAAGTG
TGCCGAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAGGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACACATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATCGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACGTCAACAACCTCAACGCACTACATCTATCAATGGACATCAAATACAACACACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATCGTCAATCAAACCATGCAATCATCGATTGCATAA

Domains

Predicted by InterproScan.

Recombinase (Recombinase)

(169-248)

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-321)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus N315

97.773

100

0.978
  ccrA Staphylococcus aureus COL

74.833

100

0.748