Detailed information NTG0445806

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: I3J23_RS10390
• Genome accession: NZ_CP065159
• Coordinates: 2009801..2010883 (+)
• Length: 360 a.a.
• NCBI ID: WP_003156401.1
• Uniprot ID: A0AAI8HS26
• Organism: Bacillus amyloliquefaciens strain GXU-1
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 2004801..2015883

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I3J23_RS10375 (I3J23_10375)	-	2004804..2005895 (+)	1092	WP_003156398.1	protein arginine kinase	-
I3J23_RS10380 (I3J23_10380)	clpC	2005892..2008324 (+)	2433	WP_007410388.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
I3J23_RS10385 (I3J23_10385)	radA/sms	2008418..2009797 (+)	1380	WP_014304212.1	DNA repair protein RadA	Machinery gene
I3J23_RS10390 (I3J23_10390)	disA	2009801..2010883 (+)	1083	WP_003156401.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
I3J23_RS10395 (I3J23_10395)	-	2010997..2012097 (+)	1101	WP_003156403.1	PIN/TRAM domain-containing protein	-
I3J23_RS10400 (I3J23_10400)	ispD	2012110..2012808 (+)	699	WP_003156405.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
I3J23_RS10405 (I3J23_10405)	ispF	2012801..2013277 (+)	477	WP_003156407.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
I3J23_RS10410 (I3J23_10410)	gltX	2013369..2014820 (+)	1452	WP_003156409.1	glutamate--tRNA ligase	-
I3J23_RS10415 (I3J23_10415)	cysE	2015131..2015784 (+)	654	WP_003156410.1	serine O-acetyltransferase	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 40671.21 Da
• Isoelectric Point: 5.5321

>NTDB_id=445806 I3J23_RS10390 WP_003156401.1 2009801..2010883(+) (disA) [Bacillus amyloliquefaciens strain GXU-1]
MEKEKKGAKQELDLSAILQFVAPGTPLRAGIENVLRANTGGLIVVGYNDKVKQVVDGGFHINTSFAPAHLYELAKMDGAI
ILSDSGQKILYANTQLMPEATISSSETGMRHRTAERVAKQTGCLVIAISERRNVITLYQDSMKYTLKDIGFILTKANQAI
QTLEKYKTILDKTITALNALEFEELVTFSDVLSVMHRYEMVLRIKNEINMYIKELGTEGHLIRLQVIELITDMEEEAALF
IKDYVKEKIKDPFVLLKELQDMSSYDLLDDSILFKLLGYPASTNLDDYVLPRGYRLLNKIPRLPMPIVENVVEAFGFLPS
ITEATVEELDDVEGIGEVRAQKIKKGLKRLQEKHYIDRQL

Nucleotide

• Length: 1083 bp

>NTDB_id=445806 I3J23_RS10390 WP_003156401.1 2009801..2010883(+) (disA) [Bacillus amyloliquefaciens strain GXU-1]
ATGGAAAAAGAGAAAAAAGGGGCGAAACAAGAGCTTGACCTGTCTGCAATTCTGCAGTTCGTTGCACCGGGCACCCCGCT
CAGAGCCGGGATAGAGAATGTACTTCGGGCAAATACAGGCGGCCTGATTGTTGTCGGGTACAATGATAAGGTAAAGCAAG
TCGTGGATGGCGGTTTTCATATTAATACATCATTTGCGCCCGCTCACTTATACGAGCTGGCCAAAATGGACGGTGCCATT
ATTTTAAGTGATTCCGGCCAGAAAATTCTTTATGCGAATACGCAGCTTATGCCGGAGGCGACCATTTCTTCTTCAGAAAC
GGGAATGAGGCACCGTACGGCGGAACGGGTGGCGAAGCAGACCGGCTGTCTCGTCATCGCCATTTCTGAGCGCAGAAATG
TCATTACGTTATATCAGGACAGCATGAAGTACACACTAAAGGACATAGGTTTTATTTTAACAAAGGCAAATCAGGCCATT
CAAACGCTCGAGAAGTATAAAACCATTTTAGACAAAACAATTACGGCTCTAAACGCATTAGAGTTTGAGGAGCTTGTGAC
ATTCAGTGACGTGCTGTCTGTCATGCATCGGTATGAAATGGTGCTCCGAATAAAAAATGAAATCAATATGTATATTAAAG
AACTCGGAACGGAAGGCCACTTAATCCGTCTGCAGGTGATTGAACTGATTACGGACATGGAAGAAGAGGCGGCACTTTTC
ATCAAAGACTATGTCAAAGAAAAAATCAAAGATCCGTTCGTGCTGTTAAAAGAGCTCCAGGATATGTCCAGCTATGATCT
GCTGGATGATTCCATTCTGTTTAAACTGCTTGGATACCCGGCTTCTACGAATCTTGATGATTATGTGCTCCCGAGAGGCT
ACAGGCTGCTGAACAAAATTCCGCGTCTGCCGATGCCGATTGTTGAAAATGTGGTTGAGGCGTTCGGATTTTTGCCAAGC
ATAACGGAAGCCACTGTAGAAGAGCTTGATGATGTCGAGGGTATCGGCGAAGTGCGCGCCCAAAAAATCAAAAAAGGCTT
AAAACGCCTTCAGGAAAAACACTATATAGATAGACAGCTTTAA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (29-141)

• DisA bacterial checkpoint controller linker region (DisA-linker) (146-284)

3D structure

• AlphaFold DB: A0AAI8HS26

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	94.444	100	0.944