Detailed information NTG0044543

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: MGAS1882_RS06665
• Genome accession: NC_017053
• Coordinates: 1351837..1352562 (-)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes MGAS1882
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 1346837..1357562

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS1882_RS06630 (MGAS1882_1370)	rnpM	1346871..1347167 (-)	297	WP_002983486.1	RNase P modulator RnpM	-
MGAS1882_RS06635 (MGAS1882_1371)	nusA	1347183..1348340 (-)	1158	WP_002988817.1	transcription termination factor NusA	-
MGAS1882_RS06640 (MGAS1882_1372)	rimP	1348515..1349051 (-)	537	WP_002988815.1	ribosome maturation factor RimP	-
MGAS1882_RS06650 (MGAS1882_1374)	trmB	1349310..1349945 (-)	636	WP_002983387.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
MGAS1882_RS06655 (MGAS1882_1375)	ccrZ	1349945..1350736 (-)	792	WP_002983385.1	cell cycle regulator CcrZ	-
MGAS1882_RS06660 (MGAS1882_1376)	-	1350800..1351834 (-)	1035	WP_002994331.1	ABC transporter permease	-
MGAS1882_RS06665 (MGAS1882_1377)	pptA	1351837..1352562 (-)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
MGAS1882_RS06670 (MGAS1882_1378)	-	1352634..1353053 (+)	420	WP_002983376.1	HIT family protein	-
MGAS1882_RS06675 (MGAS1882_1379)	-	1353050..1353406 (+)	357	WP_014407784.1	hypothetical protein	-
MGAS1882_RS06680 (MGAS1882_1380)	brpA	1353517..1354800 (-)	1284	WP_014411892.1	biofilm formation/cell division transcriptional regulator BrpA	-
MGAS1882_RS06685 (MGAS1882_1381)	-	1354809..1355333 (-)	525	WP_014407786.1	GNAT family N-acetyltransferase	-
MGAS1882_RS06690 (MGAS1882_1382)	tsaE	1355308..1355769 (-)	462	WP_002983367.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
MGAS1882_RS06695 (MGAS1882_1383)	-	1355923..1357383 (-)	1461	WP_002988645.1	NCS2 family permease	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=44543 MGAS1882_RS06665 WP_002983379.1 1351837..1352562(-) (pptA) [Streptococcus pyogenes MGAS1882]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=44543 MGAS1882_RS06665 WP_002983379.1 1351837..1352562(-) (pptA) [Streptococcus pyogenes MGAS1882]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGTTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714