Detailed information NTG0044538

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: MGAS1882_RS05870
• Genome accession: NC_017053
• Coordinates: 1184956..1185993 (-)
• Length: 345 a.a.
• NCBI ID: WP_014407697.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes MGAS1882
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1179956..1190993

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS1882_RS05850 (MGAS1882_1205)	-	1180694..1181320 (+)	627	WP_002983834.1	prepilin peptidase	-
MGAS1882_RS05855 (MGAS1882_1206)	rlmN	1181402..1182481 (-)	1080	WP_002992788.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
MGAS1882_RS05860 (MGAS1882_1207)	-	1182485..1183105 (-)	621	WP_002992791.1	YutD family protein	-
MGAS1882_RS05865 (MGAS1882_1208)	-	1183553..1184530 (-)	978	WP_002994809.1	LacI family DNA-binding transcriptional regulator	-
MGAS1882_RS05870 (MGAS1882_1209)	sepM	1184956..1185993 (-)	1038	WP_014407697.1	SepM family pheromone-processing serine protease	Regulator
MGAS1882_RS05875 (MGAS1882_1210)	coaD	1185980..1186471 (-)	492	WP_014407698.1	pantetheine-phosphate adenylyltransferase	-
MGAS1882_RS05880 (MGAS1882_1211)	rsmD	1186461..1187000 (-)	540	WP_002983819.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
MGAS1882_RS05885 (MGAS1882_1212)	asnA	1187123..1188115 (-)	993	WP_014407699.1	aspartate--ammonia ligase	-
MGAS1882_RS05890 (MGAS1882_1213)	arcC	1188429..1189379 (-)	951	WP_009880962.1	carbamate kinase	-
MGAS1882_RS05895 (MGAS1882_1214)	-	1189399..1190730 (-)	1332	WP_014407700.1	dipeptidase	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37571.33 Da
• Isoelectric Point: 9.6692

>NTDB_id=44538 MGAS1882_RS05870 WP_014407697.1 1184956..1185993(-) (sepM) [Streptococcus pyogenes MGAS1882]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGMLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide

• Length: 1038 bp

>NTDB_id=44538 MGAS1882_RS05870 WP_014407697.1 1184956..1185993(-) (sepM) [Streptococcus pyogenes MGAS1882]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAATGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGAGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAACGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (129-192)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-309)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.275	100	0.693