Detailed information NTG0444848

Bioinformatically predicted

Overview

• Name: hexB
• Type: Machinery gene
• Locus tag: IXH55_RS01135
• Genome accession: NZ_CP064772
• Coordinates: 256766..257932 (-)
• Length: 388 a.a.
• NCBI ID: WP_001806223.1
• Uniprot ID: B1VKA9
• Organism: Staphylococcus aureus strain TCH32767
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 251766..262932

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IXH55_RS01115 (IXH55_01110)	glpK	252459..253955 (-)	1497	WP_000417372.1	glycerol kinase GlpK	-
IXH55_RS01120 (IXH55_01115)	-	254084..254901 (-)	818	Protein_222	MIP/aquaporin family protein	-
IXH55_RS01125 (IXH55_01120)	-	255376..255918 (-)	543	WP_001077635.1	glycerol-3-phosphate responsive antiterminator	-
IXH55_RS01130	-	255924..256793 (-)	870	WP_001806221.1	DNA mismatch repair protein	-
IXH55_RS01135	hexB	256766..257932 (-)	1167	WP_001806223.1	DNA mismatch repair endonuclease MutL	Machinery gene
IXH55_RS01140 (IXH55_01130)	hexA	257945..260563 (-)	2619	WP_000073352.1	DNA mismatch repair protein MutS	Machinery gene
IXH55_RS01145 (IXH55_01135)	thiW	260866..261357 (-)	492	WP_000842277.1	energy coupling factor transporter S component ThiW	-
IXH55_RS01150 (IXH55_01140)	-	261384..261749 (-)	366	WP_000282386.1	RicAFT regulatory complex protein RicA family protein	-

Sequence

Protein

• Length: 388 a.a.
• Molecular weight: 43902.64 Da
• Isoelectric Point: 9.7302

>NTDB_id=444848 IXH55_RS01135 WP_001806223.1 256766..257932(-) (hexB) [Staphylococcus aureus strain TCH32767]
MGKIKELQTSLANKIAAGEVVERPSSVVKELLENAIDAGATEISIEVEESGVQSIRVVDNGSGIEAEDLGLVFHRHATSK
LDQDEDLFHIRTLGFRGEALASISSVAKVTLKTCTDNANGNEIYVENGEILNHKPAKAKKGTDILVESLFYNTPARLKYI
KSLYTELGKITDIVNRMAMSHPDIRIALISDGKTMLSTNGSGRTNEVMAEIYGMKVARDLVHISGDTSDYHIEGFVAKPE
HSRSNKHYISIFINGRYIKNFMLNKAILEGYHTLLTIGRFPICYINIEMDPILVDVNVHPTKLEVRLSKEEQLYQLIVSK
IQEAFKDRILIPKNNLDYVPKKIKYYIHSNNKKSNLNKDKTQRITKRRRFHLKKVTVSHLWQKIKTMR

Nucleotide

• Length: 1167 bp

>NTDB_id=444848 IXH55_RS01135 WP_001806223.1 256766..257932(-) (hexB) [Staphylococcus aureus strain TCH32767]
ATGGGGAAAATTAAAGAACTCCAAACCTCATTAGCAAATAAAATCGCAGCAGGTGAAGTAGTTGAAAGACCGAGTTCTGT
TGTGAAAGAACTGTTGGAAAATGCTATAGATGCAGGCGCTACAGAAATAAGCATTGAAGTAGAGGAATCTGGCGTCCAAT
CTATTCGCGTAGTCGATAATGGAAGCGGAATTGAAGCGGAAGACTTAGGATTAGTATTTCATAGACATGCGACTAGTAAA
TTAGATCAAGATGAAGATTTATTTCATATTAGGACATTAGGATTCCGTGGTGAAGCACTAGCCAGTATTTCATCAGTTGC
TAAAGTAACATTGAAGACTTGCACGGATAATGCTAATGGAAATGAAATATATGTAGAAAATGGTGAAATATTAAATCATA
AGCCTGCAAAAGCGAAAAAAGGAACAGATATACTTGTAGAATCATTATTTTATAATACACCAGCACGTTTAAAATATATT
AAAAGTTTATACACTGAACTAGGTAAAATAACAGATATTGTCAATAGAATGGCTATGAGCCATCCGGACATTCGAATAGC
ACTCATTTCAGATGGCAAAACAATGTTAAGTACAAATGGTTCAGGACGAACTAATGAAGTGATGGCAGAGATTTATGGGA
TGAAAGTTGCACGAGATTTAGTACATATATCTGGAGATACAAGTGATTATCACATTGAAGGTTTTGTTGCAAAGCCTGAA
CATTCTAGAAGTAATAAGCACTATATTTCTATTTTTATTAATGGACGATACATTAAAAACTTTATGCTAAATAAAGCGAT
TTTAGAAGGCTATCATACACTCTTAACAATAGGTAGGTTCCCGATTTGTTATATTAATATTGAAATGGATCCAATCTTAG
TAGACGTAAATGTTCATCCAACAAAACTAGAAGTGCGTTTATCAAAAGAAGAGCAACTATATCAATTGATAGTGAGCAAA
ATACAAGAAGCATTTAAAGACCGTATATTAATTCCTAAAAATAACTTGGATTATGTGCCAAAAAAAATAAAGTATTATAT
TCATTCGAACAACAAAAAATCGAATTTGAACAAAGACAAAACACAGAGAATAACCAAGAGAAGACGTTTTCATCTGAAGA
AAGTAACAGTAAGTCATTTATGGCAGAAAATCAAAACGATGAGATAG

Domains

Predicted by InterProScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3) (25-119)

• DNA mismatch repair protein, C-terminal domain (DNA_mis_repair) (209-325)

3D structure

• AlphaFold DB: B1VKA9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexB	Streptococcus pneumoniae R6	53.153	85.825	0.456