Detailed information    

insolico Bioinformatically predicted

Overview

Name   treR   Type   Regulator
Locus tag   MGAS15252_RS07875 Genome accession   NC_017040
Coordinates   1642408..1643121 (+) Length   237 a.a.
NCBI ID   WP_014407926.1    Uniprot ID   -
Organism   Streptococcus pyogenes MGAS15252     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1637408..1648121
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGAS15252_RS07865 (MGAS15252_1627) treC 1638478..1640106 (-) 1629 WP_014407924.1 alpha,alpha-phosphotrehalase -
  MGAS15252_RS07870 (MGAS15252_1628) treP 1640173..1642197 (-) 2025 WP_014407925.1 PTS system trehalose-specific EIIBC component -
  MGAS15252_RS07875 (MGAS15252_1629) treR 1642408..1643121 (+) 714 WP_014407926.1 trehalose operon repressor Regulator
  MGAS15252_RS07880 (MGAS15252_1631) - 1643400..1643738 (-) 339 WP_014407927.1 winged helix-turn-helix transcriptional regulator -
  MGAS15252_RS07885 (MGAS15252_1632) - 1643925..1644782 (+) 858 WP_014407928.1 VOC family protein -
  MGAS15252_RS07890 (MGAS15252_1633) yaaA 1644824..1645555 (+) 732 WP_014407929.1 peroxide stress protein YaaA -
  MGAS15252_RS07895 (MGAS15252_1634) nrdG 1645729..1646343 (-) 615 WP_002982219.1 anaerobic ribonucleoside-triphosphate reductase activating protein -
  MGAS15252_RS07900 (MGAS15252_1635) - 1646358..1646852 (-) 495 WP_014407930.1 GNAT family N-acetyltransferase -
  MGAS15252_RS07905 (MGAS15252_1636) - 1646861..1647796 (-) 936 WP_009880789.1 Gfo/Idh/MocA family protein -
  MGAS15252_RS09105 (MGAS15252_1637) - 1647825..1647971 (-) 147 WP_002982210.1 hypothetical protein -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27619.81 Da        Isoelectric Point: 9.7515

>NTDB_id=44417 MGAS15252_RS07875 WP_014407926.1 1642408..1643121(+) (treR) [Streptococcus pyogenes MGAS15252]
MTKYERIYKDLETKINKNFYKEGDFLPTEIELSQQYQASRDTVRKALSLLTKAGLILKKQGRGTQVIRHHQIMFPISELT
SYQELVSYSNLDSKTNVIAIDKLIVDETLSKLTGFSKNSLVWRVTRQRVVEGVASVLDIDYLSKTLVPIMTREIAEHSIY
QYLEKELHLAIDFALKEVTIDQITDRDKILLDLGSDQHVVSVKSKVYLSNNNQFQFTESRHKLEKFKFLDFARRRPK

Nucleotide


Download         Length: 714 bp        

>NTDB_id=44417 MGAS15252_RS07875 WP_014407926.1 1642408..1643121(+) (treR) [Streptococcus pyogenes MGAS15252]
ATGACAAAGTATGAACGTATTTATAAAGACCTCGAAACAAAAATAAACAAAAACTTTTACAAAGAAGGGGATTTTTTACC
TACTGAAATAGAATTGAGTCAACAATACCAAGCTAGCCGAGATACCGTCCGCAAGGCTCTCTCACTTCTCACAAAGGCAG
GTCTTATCCTCAAAAAACAAGGACGTGGCACCCAAGTGATTAGACATCATCAGATCATGTTCCCTATCTCAGAACTAACT
AGTTATCAGGAACTCGTCTCTTACTCAAATCTAGATTCTAAGACCAACGTCATTGCCATTGATAAACTGATTGTGGATGA
GACACTTTCAAAATTGACCGGTTTTAGCAAAAACAGCTTGGTCTGGCGTGTTACACGCCAACGCGTTGTTGAGGGTGTGG
CTTCCGTCTTAGACATTGATTACCTTAGTAAAACTTTGGTGCCAATAATGACAAGGGAAATCGCAGAGCATTCTATTTAT
CAATATTTGGAAAAGGAACTCCATCTCGCCATTGACTTTGCCCTCAAAGAGGTTACCATTGACCAAATAACCGATCGTGA
TAAAATTTTACTTGACCTTGGATCAGACCAACATGTTGTTTCCGTCAAATCCAAAGTCTACCTTTCCAATAATAACCAAT
TCCAATTCACCGAGAGTCGCCATAAACTGGAAAAATTTAAATTTTTAGATTTTGCTCGGCGCAGACCAAAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, gntR family (GntR)

(3-66)

UTRA domain (UTRA)

(91-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  treR Streptococcus mutans UA159

68.376

98.734

0.675

Multiple sequence alignment