Detailed information NTG0044412

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: MGAS15252_RS06375
• Genome accession: NC_017040
• Coordinates: 1310176..1310901 (-)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes MGAS15252
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 1305176..1315901

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS15252_RS06340 (MGAS15252_1309)	rnpM	1305210..1305506 (-)	297	WP_002983486.1	RNase P modulator RnpM	-
MGAS15252_RS06345 (MGAS15252_1310)	nusA	1305522..1306679 (-)	1158	WP_002988817.1	transcription termination factor NusA	-
MGAS15252_RS06350 (MGAS15252_1311)	rimP	1306854..1307390 (-)	537	WP_002988815.1	ribosome maturation factor RimP	-
MGAS15252_RS06360 (MGAS15252_1313)	trmB	1307649..1308284 (-)	636	WP_002983387.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
MGAS15252_RS06365 (MGAS15252_1314)	ccrZ	1308284..1309075 (-)	792	WP_002983385.1	cell cycle regulator CcrZ	-
MGAS15252_RS06370 (MGAS15252_1315)	-	1309139..1310173 (-)	1035	WP_002994331.1	ABC transporter permease	-
MGAS15252_RS06375 (MGAS15252_1316)	pptA	1310176..1310901 (-)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
MGAS15252_RS06380 (MGAS15252_1317)	-	1310973..1311392 (+)	420	WP_014407783.1	HIT family protein	-
MGAS15252_RS06385 (MGAS15252_1318)	-	1311389..1311745 (+)	357	WP_014407784.1	hypothetical protein	-
MGAS15252_RS06390 (MGAS15252_1319)	brpA	1311856..1313139 (-)	1284	WP_014407785.1	biofilm formation/cell division transcriptional regulator BrpA	-
MGAS15252_RS06395 (MGAS15252_1320)	-	1313148..1313672 (-)	525	WP_014407786.1	GNAT family N-acetyltransferase	-
MGAS15252_RS06400 (MGAS15252_1321)	tsaE	1313647..1314108 (-)	462	WP_002983367.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
MGAS15252_RS06405 (MGAS15252_1322)	-	1314262..1315722 (-)	1461	WP_002988645.1	NCS2 family permease	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=44412 MGAS15252_RS06375 WP_002983379.1 1310176..1310901(-) (pptA) [Streptococcus pyogenes MGAS15252]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=44412 MGAS15252_RS06375 WP_002983379.1 1310176..1310901(-) (pptA) [Streptococcus pyogenes MGAS15252]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGTTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714