Detailed information NTG0044407

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: MGAS15252_RS05580
• Genome accession: NC_017040
• Coordinates: 1143297..1144334 (-)
• Length: 345 a.a.
• NCBI ID: WP_014407697.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes MGAS15252
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1138297..1149334

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS15252_RS05560 (MGAS15252_1144)	-	1139035..1139661 (+)	627	WP_002983834.1	prepilin peptidase	-
MGAS15252_RS05565 (MGAS15252_1145)	rlmN	1139743..1140822 (-)	1080	WP_002992788.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
MGAS15252_RS05570 (MGAS15252_1146)	-	1140826..1141446 (-)	621	WP_002992791.1	YutD family protein	-
MGAS15252_RS05575 (MGAS15252_1147)	-	1141894..1142871 (-)	978	WP_002994809.1	LacI family DNA-binding transcriptional regulator	-
MGAS15252_RS05580 (MGAS15252_1148)	sepM	1143297..1144334 (-)	1038	WP_014407697.1	SepM family pheromone-processing serine protease	Regulator
MGAS15252_RS05585 (MGAS15252_1149)	coaD	1144321..1144812 (-)	492	WP_014407698.1	pantetheine-phosphate adenylyltransferase	-
MGAS15252_RS05590 (MGAS15252_1150)	rsmD	1144802..1145341 (-)	540	WP_002983819.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
MGAS15252_RS05595 (MGAS15252_1151)	asnA	1145464..1146456 (-)	993	WP_014407699.1	aspartate--ammonia ligase	-
MGAS15252_RS05600 (MGAS15252_1152)	arcC	1146770..1147720 (-)	951	WP_009880962.1	carbamate kinase	-
MGAS15252_RS05605 (MGAS15252_1153)	-	1147740..1149071 (-)	1332	WP_014407700.1	dipeptidase	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37571.33 Da
• Isoelectric Point: 9.6692

>NTDB_id=44407 MGAS15252_RS05580 WP_014407697.1 1143297..1144334(-) (sepM) [Streptococcus pyogenes MGAS15252]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGMLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide

• Length: 1038 bp

>NTDB_id=44407 MGAS15252_RS05580 WP_014407697.1 1143297..1144334(-) (sepM) [Streptococcus pyogenes MGAS15252]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAATGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGAGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAACGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (129-192)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-309)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.275	100	0.693