Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiE   Type   Regulator
Locus tag   MGAS15252_RS01340 Genome accession   NC_017040
Coordinates   259976..261046 (+) Length   356 a.a.
NCBI ID   WP_002992231.1    Uniprot ID   A0A5S4TWS5
Organism   Streptococcus pyogenes MGAS15252     
Function   internalize XIP (predicted from homology)   
Competence regulation

Genomic Context

Location: 254976..266046
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGAS15252_RS01325 (MGAS15252_0274) amiA 255504..257474 (+) 1971 WP_014407301.1 peptide ABC transporter substrate-binding protein Regulator
  MGAS15252_RS01330 (MGAS15252_0275) amiC 257539..259041 (+) 1503 WP_014407302.1 ABC transporter permease Regulator
  MGAS15252_RS01335 (MGAS15252_0276) amiD 259041..259967 (+) 927 WP_014407303.1 oligopeptide ABC transporter permease OppC Regulator
  MGAS15252_RS01340 (MGAS15252_0277) amiE 259976..261046 (+) 1071 WP_002992231.1 ABC transporter ATP-binding protein Regulator
  MGAS15252_RS01345 (MGAS15252_0278) amiF 261039..261962 (+) 924 WP_002986000.1 ATP-binding cassette domain-containing protein Regulator
  MGAS15252_RS09325 - 262000..262089 (-) 90 WP_110002794.1 IS3 family transposase -
  MGAS15252_RS09330 - 262219..262535 (-) 317 Protein_235 IS3 family transposase -

Sequence

Protein


Download         Length: 356 a.a.        Molecular weight: 39680.74 Da        Isoelectric Point: 5.4774

>NTDB_id=44388 MGAS15252_RS01340 WP_002992231.1 259976..261046(+) (amiE) [Streptococcus pyogenes MGAS15252]
MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFVGESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQEL
TDLKTNKEWAKIRGSKIATIFQDPMTSLSPIKTIGSQITEVIIKHQKVSNAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITHDLGVVASIADKVAVMYAGEIVE
FGTVEEIFYDPRHPYTWSLLSSLPQLADESGELYAIPGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAK
TWLLHPEAPKVQKPEVIQDLHQKILRKMSQQEEGNV

Nucleotide


Download         Length: 1071 bp        

>NTDB_id=44388 MGAS15252_RS01340 WP_002992231.1 259976..261046(+) (amiE) [Streptococcus pyogenes MGAS15252]
ATGACAAAAGAAAATAATGTAATCTTAACTGCCAAAGATGTGGTGGTAGAATTTGATGTGCGTGATCGTGTTTTAACAGC
TATCCGTAACGTCTCACTGGAACTTGTTGAAGGAGAAGTCCTTGCTTTTGTAGGGGAATCAGGCTCAGGTAAATCTGTTT
TAACAAAGACCTTTACAGGGATGTTGGAGTCTAATGGACGCATTGCTAATGGTTCAATTGTCTATCGTGGGCAAGAATTG
ACAGATTTAAAAACAAATAAAGAGTGGGCAAAGATTCGCGGCTCAAAAATCGCAACGATTTTCCAAGACCCAATGACCAG
TCTTAGTCCCATTAAAACTATCGGTAGCCAAATCACAGAAGTGATTATTAAGCACCAAAAAGTAAGTAATGCCAAAGCTA
AAGAAATGGCCCTTGATTACATGAATAAAGTGGGTATCCCAAATGCCAAAAAACGCTTTGAAGATTACCCATTTGAGTAT
TCAGGAGGAATGCGTCAACGTATTGTTATCGCTATTGCTTTAGCTTGTCGCCCAGATATTCTTATCTGTGATGAGCCAAC
AACAGCCCTTGATGTGACTATTCAAGCTCAAATCGTTGAGTTATTGAAGTCGCTTCAACGAGAATATCATTTCACCATTA
TCTTTATTACGCACGATTTAGGTGTTGTGGCAAGCATTGCAGATAAAGTGGCTGTCATGTATGCAGGAGAAATTGTTGAA
TTTGGAACAGTCGAAGAGATTTTCTATGATCCAAGACACCCCTATACATGGAGTTTGCTGTCTAGCTTACCGCAGTTGGC
AGATGAATCTGGTGAACTTTACGCTATTCCAGGAACGCCTCCATCACTTTATTCACCAATTATCGGAGATGCCTTTGCAC
TTCGCTCAGAATATGCTATGGTTTTAGACTTTGAAAAAGCACCTCCGGCGATTAACGTATCTGAGACTCATTGGGCCAAA
ACATGGCTTTTACACCCAGAGGCTCCAAAAGTTCAAAAACCAGAAGTCATTCAAGATTTGCATCAAAAAATCTTAAGGAA
AATGTCACAACAGGAGGAAGGAAATGTCTGA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(29-187)

Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY)

(239-299)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5S4TWS5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiE Streptococcus salivarius strain HSISS4

76.667

100

0.775
  amiE Streptococcus thermophilus LMG 18311

75.556

100

0.764
  amiE Streptococcus thermophilus LMD-9

75.556

100

0.764
  oppD Streptococcus mutans UA159

56.677

94.663

0.537

Multiple sequence alignment