Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB10   Type   Machinery gene
Locus tag   C528_RS01150 Genome accession   NZ_CP053256
Coordinates   251730..252866 (+) Length   378 a.a.
NCBI ID   WP_001916843.1    Uniprot ID   A0AAE7AMX2
Organism   Helicobacter pylori A45     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 246730..257866
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C528_RS01115 (C528_001115) panD 247181..247534 (+) 354 WP_001916849.1 aspartate 1-decarboxylase -
  C528_RS01120 (C528_001120) - 247537..247839 (+) 303 WP_000347926.1 YbaB/EbfC family nucleoid-associated protein -
  C528_RS01125 (C528_001125) - 247839..248834 (+) 996 WP_001916848.1 PDZ domain-containing protein -
  C528_RS01130 (C528_001130) comB6 248842..249897 (+) 1056 WP_171407256.1 P-type conjugative transfer protein TrbL Machinery gene
  C528_RS01135 (C528_001135) comB7 249913..250026 (+) 114 WP_001217868.1 hypothetical protein Machinery gene
  C528_RS01140 (C528_001140) comB8 250023..250760 (+) 738 WP_001916845.1 virB8 family protein Machinery gene
  C528_RS01145 (C528_001145) comB9 250760..251737 (+) 978 WP_001916844.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  C528_RS01150 (C528_001150) comB10 251730..252866 (+) 1137 WP_001916843.1 DNA type IV secretion system protein ComB10 Machinery gene
  C528_RS01155 (C528_001155) - 252937..254349 (+) 1413 WP_001916842.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  C528_RS01160 (C528_001160) gmd 254379..255524 (+) 1146 WP_001916841.1 GDP-mannose 4,6-dehydratase -
  C528_RS01165 (C528_001165) - 255517..256449 (+) 933 WP_001916840.1 GDP-L-fucose synthase -
  C528_RS01170 (C528_001170) hypE 256718..257716 (-) 999 WP_001916839.1 hydrogenase expression/formation protein HypE -

Sequence

Protein


Download         Length: 378 a.a.        Molecular weight: 42299.83 Da        Isoelectric Point: 9.8541

>NTDB_id=443770 C528_RS01150 WP_001916843.1 251730..252866(+) (comB10) [Helicobacter pylori A45]
MNKWLKGVVVFVGGFATIITTSLIYHQKPKAPLNNQQSLLNDDEVKYPLQDYTFTQNPQPTNIESSKDATIKALQEQLKA
ALKALNSKEMNHSKEETFTSPPIDLKTNTTHPKKDFSSKQLDLLAARITPFKQSPKNYEENLIFPMDNPKGIDGFTNLKE
KDTATNENKLLRTITADKMIPAFLITPISSQIAGKVIAQVESDIFAHMGKAVLIPKGSKVIGYYSNNNKMGEYRLDIVWS
RIITPHGINIMLTNAKGADIKGYNGLVGELIERNFQRYGVPLLLSTLTNGLLIGITSALNNRGNKEEVTNFFGDYLLMQL
MRQSGMGINQVVNQILRDKSKIAPIVVIREGSRVFISPNTDIFFPIPRENEVIAEFLK

Nucleotide


Download         Length: 1137 bp        

>NTDB_id=443770 C528_RS01150 WP_001916843.1 251730..252866(+) (comB10) [Helicobacter pylori A45]
ATGAATAAATGGCTTAAGGGGGTGGTTGTTTTTGTGGGGGGTTTTGCAACGATTATAACAACTTCTTTAATCTATCATCA
AAAGCCAAAAGCCCCTTTAAATAACCAACAAAGCCTTTTGAATGACGATGAGGTGAAATACCCCTTACAAGACTACACCT
TCACCCAAAACCCACAGCCAACTAATATAGAAAGCTCCAAAGACGCTACCATCAAAGCCTTACAAGAACAGCTAAAAGCC
GCTTTAAAAGCCCTAAACTCCAAAGAAATGAACCACTCTAAAGAAGAAACTTTTACTAGCCCTCCCATAGATTTAAAAAC
AAACACAACCCATCCTAAAAAAGACTTTTCTTCAAAGCAATTAGATTTACTAGCTGCTCGCATCACCCCTTTCAAACAAA
GCCCTAAAAATTACGAAGAAAACCTGATCTTCCCCATGGATAACCCTAAAGGCATTGATGGTTTTACTAACCTTAAAGAA
AAAGACACCGCTACCAATGAAAACAAGCTTCTACGCACCATTACAGCCGATAAAATGATACCCGCCTTTTTGATCACGCC
TATTTCTAGCCAGATCGCTGGTAAAGTGATTGCGCAAGTGGAGAGCGATATTTTTGCTCACATGGGCAAGGCCGTCTTAA
TCCCTAAAGGCTCTAAAGTCATAGGCTATTACAGCAACAATAACAAAATGGGCGAATACCGCCTGGATATTGTATGGAGC
CGCATCATCACCCCTCATGGCATCAATATCATGCTCACTAACGCTAAAGGAGCGGACATTAAAGGCTATAACGGCTTAGT
GGGGGAATTGATTGAAAGGAATTTCCAGCGCTATGGCGTGCCGTTACTGCTTTCTACTCTCACTAACGGCCTATTGATTG
GGATCACTTCAGCTTTAAACAACAGGGGCAATAAAGAAGAGGTGACCAATTTCTTTGGGGATTATCTTTTAATGCAATTG
ATGAGGCAAAGCGGCATGGGGATCAATCAAGTGGTCAATCAAATTTTAAGAGACAAGAGCAAAATCGCTCCCATTGTGGT
GATTAGAGAAGGGAGTAGGGTATTCATTTCGCCCAATACTGACATCTTTTTTCCTATACCCAGAGAGAATGAAGTCATCG
CTGAGTTTTTGAAGTGA

Domains

Predicted by InterproScan.

Bacterial conjugation TrbI-like protein (TrbI)

(173-364)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB10 Helicobacter pylori P1

95.238

100

0.952