Detailed information NTG0443350

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: HLG72_RS13625
• Genome accession: NZ_CP053185
• Coordinates: 2733241..2734128 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143422.1
• Uniprot ID: A0AB73JC73
• Organism: Staphylococcus aureus strain Guangzhou-SAU749
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2728241..2739128

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HLG72_RS13595 (HLG72_13615)	-	2728334..2728426 (+)	93	WP_010956583.1	hypothetical protein	-
HLG72_RS13600 (HLG72_13620)	-	2728534..2729031 (-)	498	WP_001065268.1	glutathione peroxidase	-
HLG72_RS13605 (HLG72_13625)	-	2729041..2729301 (-)	261	WP_011382405.1	hypothetical protein	-
HLG72_RS13610 (HLG72_13630)	-	2729683..2729796 (-)	114	WP_078065157.1	hypothetical protein	-
HLG72_RS13615 (HLG72_13635)	-	2730465..2732381 (-)	1917	WP_170833580.1	ABC transporter permease	-
HLG72_RS13620 (HLG72_13640)	-	2732378..2733133 (-)	756	WP_000923775.1	ABC transporter ATP-binding protein	-
HLG72_RS13625 (HLG72_13645)	braS	2733241..2734128 (-)	888	WP_000143422.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
HLG72_RS13630 (HLG72_13650)	braR	2734139..2734804 (-)	666	WP_000697884.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
HLG72_RS13635 (HLG72_13655)	-	2734830..2735030 (-)	201	WP_000604725.1	hypothetical protein	-
HLG72_RS13640 (HLG72_13660)	-	2735228..2736652 (+)	1425	WP_000953738.1	alkaline phosphatase	-
HLG72_RS14385	-	2736712..2736813 (-)	102	WP_000731972.1	SE2200 family small protein	-
HLG72_RS13650 (HLG72_13670)	-	2736935..2737390 (-)	456	WP_000106183.1	MarR family winged helix-turn-helix transcriptional regulator	-
HLG72_RS13655 (HLG72_13675)	-	2737635..2738396 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34031.29 Da
• Isoelectric Point: 5.8962

>NTDB_id=443350 HLG72_RS13625 WP_000143422.1 2733241..2734128(-) (braS) [Staphylococcus aureus strain Guangzhou-SAU749]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGVGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=443350 HLG72_RS13625 WP_000143422.1 2733241..2734128(-) (braS) [Staphylococcus aureus strain Guangzhou-SAU749]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTGTTGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99