Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   HLG72_RS10350 Genome accession   NZ_CP053185
Coordinates   2084132..2084848 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain Guangzhou-SAU749     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2079132..2089848
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HLG72_RS10320 (HLG72_10325) - 2079349..2079975 (+) 627 WP_000522383.1 nitroreductase family protein -
  HLG72_RS10325 (HLG72_10330) - 2080336..2081121 (+) 786 WP_000867953.1 carbon-nitrogen family hydrolase -
  HLG72_RS14315 hld 2081720..2081800 (-) 81 WP_000046023.1 delta-hemolysin -
  HLG72_RS10335 (HLG72_10340) agrB 2082090..2082659 (+) 570 WP_001105712.1 accessory gene regulator AgrB -
  HLG72_RS10340 (HLG72_10345) agrD 2082656..2082796 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  HLG72_RS10345 (HLG72_10350) agrC 2082821..2084113 (+) 1293 WP_031844950.1 quorum-sensing sensor histidine kinase AgrC -
  HLG72_RS10350 (HLG72_10355) agrA 2084132..2084848 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  HLG72_RS10355 (HLG72_10360) - 2084920..2085027 (+) 108 WP_031844951.1 hypothetical protein -
  HLG72_RS10360 (HLG72_10365) - 2085215..2086174 (-) 960 WP_001253300.1 carbohydrate kinase -
  HLG72_RS10365 (HLG72_10370) - 2086171..2087655 (-) 1485 WP_000141422.1 sucrose-6-phosphate hydrolase -
  HLG72_RS10370 (HLG72_10375) - 2087804..2088754 (-) 951 WP_000790321.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=443346 HLG72_RS10350 WP_000688492.1 2084132..2084848(+) (agrA) [Staphylococcus aureus strain Guangzhou-SAU749]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=443346 HLG72_RS10350 WP_000688492.1 2084132..2084848(+) (agrA) [Staphylococcus aureus strain Guangzhou-SAU749]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACGTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1