Detailed information NTG0442850

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: HK402_RS14040
• Genome accession: NZ_CP053075
• Coordinates: 2781309..2782196 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain SA01
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2776309..2787196

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HK402_RS14010 (HK402_14025)	-	2776328..2776420 (+)	93	WP_010956583.1	hypothetical protein	-
HK402_RS14015 (HK402_14030)	-	2776528..2777025 (-)	498	WP_001065268.1	glutathione peroxidase	-
HK402_RS14020 (HK402_14035)	-	2777035..2777295 (-)	261	WP_001791974.1	hypothetical protein	-
HK402_RS14025 (HK402_14040)	-	2777677..2777790 (-)	114	Protein_2739	hypothetical protein	-
HK402_RS14030 (HK402_14045)	-	2778449..2780449 (-)	2001	WP_000776751.1	ABC transporter permease	-
HK402_RS14035 (HK402_14050)	-	2780446..2781201 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
HK402_RS14040 (HK402_14055)	braS	2781309..2782196 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
HK402_RS14045 (HK402_14060)	braR	2782207..2782872 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
HK402_RS14050 (HK402_14065)	-	2782898..2783098 (-)	201	WP_000604730.1	hypothetical protein	-
HK402_RS14055 (HK402_14070)	-	2783296..2784720 (+)	1425	WP_000953755.1	alkaline phosphatase	-
HK402_RS14060 (HK402_14075)	-	2784790..2784900 (+)	111	Protein_2746	hypothetical protein	-
HK402_RS14065 (HK402_14080)	-	2785003..2785458 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
HK402_RS14070 (HK402_14085)	-	2785703..2786464 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=442850 HK402_RS14040 WP_000143425.1 2781309..2782196(-) (braS) [Staphylococcus aureus strain SA01]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=442850 HK402_RS14040 WP_000143425.1 2781309..2782196(-) (braS) [Staphylococcus aureus strain SA01]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1