Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   HHM66_RS04290 Genome accession   NZ_CP053074
Coordinates   855111..857210 (-) Length   699 a.a.
NCBI ID   WP_015057518.1    Uniprot ID   A0A9X8T363
Organism   Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A88     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 857483..858346 855111..857210 flank 273


Gene organization within MGE regions


Location: 855111..858346
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HHM66_RS04290 (HHM66_04295) clpC 855111..857210 (-) 2100 WP_015057518.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  HHM66_RS04295 (HHM66_04300) - 857483..858346 (-) 864 WP_003059989.1 IS982 family transposase -

Sequence

Protein


Download         Length: 699 a.a.        Molecular weight: 77399.04 Da        Isoelectric Point: 4.8590

>NTDB_id=442780 HHM66_RS04290 WP_015057518.1 855111..857210(-) (clpC) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A88]
MTNYYDKDTFGNMDDIFNQLMGNMGGYRSENRRYLVNGREMTPEEFQAYRQTGRLSDKGSEQPTSQGHQTKKDGILAKLG
TNLTEEARQGKLDPVIGRNHEIQDTAEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
EAGTQYRGSFEENIQNMIQEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADMLKPALSRGELTLIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHHNVILPDAVLKAAIDYSIQYIPQRSLPDKAIDLVDMTAAHLAA
QHPVTDLKSLEAEMTTQKNIQEEAVAKEDFERALTAKTRIEELQKQMDNHSEDQKVTATVNDIAESVERLTGVPVSNMGA
SDLERLKEISNRLKGHVIGQDGAVEAVARAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLALDLFGSKEAIIRLD
MSEYSDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRNPYAIVLLDEIEKADPQVITLLLQVLDDGRLTDGQGNTINFKNT
VIIATSNAGFGHQEDENTDQPTIMDRIAPYFRPEFLNRFNGVIEFNHLQKEDLEEIVDLMLAEVNQTIAKKGISLAISDD
AKAHLIELGYDHAMGVRPLRRVIEQEIRDRITDFYLDHPEVKNLQASLEQGQLVIHDKN

Nucleotide


Download         Length: 2100 bp        

>NTDB_id=442780 HHM66_RS04290 WP_015057518.1 855111..857210(-) (clpC) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A88]
ATGACAAATTATTATGACAAAGATACTTTTGGAAACATGGATGATATCTTTAATCAACTAATGGGCAATATGGGTGGCTA
TCGCAGTGAAAATCGACGCTATTTAGTGAACGGACGCGAAATGACACCTGAAGAATTCCAGGCATATCGTCAGACTGGAC
GTCTGAGCGATAAAGGTAGTGAACAACCTACATCCCAAGGTCATCAGACCAAAAAGGATGGGATTTTAGCTAAACTTGGC
ACCAACTTAACGGAAGAAGCAAGACAAGGAAAACTTGATCCTGTTATTGGTCGCAATCACGAAATTCAAGACACTGCGGA
AATTTTAGCTCGCCGAACAAAGAATAATCCTGTTCTAGTCGGAGATGCTGGTGTTGGTAAAACAGCTGTGGTTGAAGGGC
TAGCTCAAGCTATTGTGAATGGTGACGTCCCTGCTGCTATCAAAAATAAAGAAATCATTTCCATTGATATTTCTGGCCTT
GAAGCAGGCACTCAGTACCGTGGCTCCTTTGAAGAAAATATCCAAAACATGATTCAAGAGGTTAAAGAAGCTGGGAATAT
TATTCTTTTCTTTGATGAAATTCATCAAATCCTTGGTGCAGGTTCTACTGGTGGTGACTCTGGGTCTAAAGGATTAGCTG
ATATGCTAAAACCTGCTCTTTCCCGTGGTGAATTGACACTGATTGGCGCCACAACTCAAGATGAATACCGCAATACCATT
TTAAAAAATGCTGCGCTTGCTCGTCGTTTTAATGAGGTTAAGGTAAATGCACCGTCTGCTGAGGACACCTTCCATATTTT
AATGGGAATCCGAAATCTTTACGAACAACACCATAATGTTATCCTTCCGGATGCTGTTCTTAAAGCTGCGATTGACTATT
CTATTCAGTACATTCCTCAACGTAGTTTACCAGATAAAGCGATTGACTTAGTAGATATGACTGCTGCGCATTTAGCCGCT
CAGCATCCTGTGACTGACCTCAAGTCTCTAGAAGCTGAAATGACCACTCAAAAGAATATCCAAGAAGAGGCTGTGGCTAA
GGAAGATTTTGAGAGAGCTTTAACCGCTAAAACACGAATTGAAGAATTGCAAAAACAAATGGACAACCATAGCGAAGACC
AAAAGGTTACTGCTACTGTCAATGATATTGCAGAATCCGTAGAGCGCCTGACTGGTGTCCCAGTGTCCAATATGGGAGCT
AGTGATTTGGAAAGACTCAAAGAAATTAGCAACCGCTTAAAAGGACACGTGATTGGCCAAGATGGAGCTGTTGAAGCTGT
GGCTCGTGCTATTCGCCGTAATCGAGCTGGTTTTGATGATGGCAATCGTCCTATCGGTTCCTTCCTCTTTGTTGGACCAA
CAGGTGTCGGTAAGACAGAGTTAGCCAAACAGCTAGCACTGGACCTCTTTGGTTCCAAAGAGGCTATTATTCGACTTGAC
ATGTCCGAATACAGTGATCGTACTGCTGTGTCCAAGTTAATCGGGACAACTGCCGGTTATGTCGGTTATGATGATAATAA
CAATACGTTAACGGAACGAGTTCGTCGCAACCCGTATGCGATTGTTCTATTGGATGAGATTGAAAAAGCCGATCCGCAAG
TCATTACCCTTCTTCTCCAAGTACTGGATGATGGCCGATTAACAGATGGTCAGGGAAATACCATCAACTTTAAAAACACT
GTTATCATTGCTACTTCTAATGCTGGATTTGGGCATCAAGAAGATGAAAATACTGATCAACCTACTATTATGGACCGTAT
TGCACCTTACTTTAGACCAGAGTTTCTCAATCGTTTCAATGGGGTTATCGAATTCAATCATCTGCAAAAAGAAGACTTAG
AAGAAATTGTTGATTTAATGTTAGCGGAAGTTAATCAAACCATAGCTAAAAAAGGAATCAGCTTAGCTATCTCTGATGAT
GCTAAAGCTCACTTGATTGAATTAGGTTATGACCACGCAATGGGAGTTCGACCATTACGCCGTGTCATCGAGCAAGAAAT
CCGAGACCGCATTACAGACTTTTACCTCGATCACCCAGAGGTCAAAAACTTACAAGCTAGTCTGGAACAAGGACAGTTAG
TCATTCACGACAAAAACTAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(608-679)

AAA lid domain (AAA_lid_9)

(259-353)

ATPase family associated with various cellular activities (AAA) (AAA)

(118-250)

AAA domain (Cdc48 subfamily) (AAA_2)

(443-600)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. cremoris KW2

47.391

100

0.481
  clpE Streptococcus mutans UA159

46.544

100

0.472
  clpE Streptococcus pneumoniae Rx1

48.447

92.132

0.446
  clpE Streptococcus pneumoniae D39

48.447

92.132

0.446
  clpE Streptococcus pneumoniae R6

48.447

92.132

0.446
  clpE Streptococcus pneumoniae TIGR4

48.367

91.989

0.445
  clpC Bacillus subtilis subsp. subtilis str. 168

44.341

92.275

0.409
  clpC Streptococcus pneumoniae Rx1

40.943

97.139

0.398
  clpC Streptococcus pneumoniae D39

40.943

97.139

0.398
  clpC Streptococcus pneumoniae TIGR4

40.795

97.139

0.396
  clpC Streptococcus thermophilus LMG 18311

43.065

88.698

0.382
  clpC Streptococcus thermophilus LMD-9

43.065

88.698

0.382
  clpC Streptococcus mutans UA159

42.903

88.698

0.381
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

42.165

88.555

0.373