Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   HKK59_RS08050 Genome accession   NZ_CP053027
Coordinates   1606249..1606938 (-) Length   229 a.a.
NCBI ID   WP_000516680.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain 01173     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1601249..1611938
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HKK59_RS08030 (HKK59_08055) dnaI 1602052..1602954 (-) 903 WP_000843627.1 primosomal protein DnaI -
  HKK59_RS08035 (HKK59_08060) - 1602951..1604126 (-) 1176 WP_000074512.1 DnaD domain protein -
  HKK59_RS08040 (HKK59_08065) nrdR 1604126..1604605 (-) 480 WP_001203682.1 transcriptional regulator NrdR -
  HKK59_RS08045 (HKK59_08070) - 1604754..1606259 (-) 1506 WP_000791116.1 HAMP domain-containing histidine kinase -
  HKK59_RS08050 (HKK59_08075) covR 1606249..1606938 (-) 690 WP_000516680.1 response regulator transcription factor Regulator
  HKK59_RS08055 (HKK59_08080) - 1607173..1607706 (-) 534 WP_000927543.1 DUF177 domain-containing protein -
  HKK59_RS08060 (HKK59_08085) htpX 1607811..1608701 (-) 891 WP_000966817.1 zinc metalloprotease HtpX -
  HKK59_RS08065 (HKK59_08090) - 1608722..1609276 (-) 555 WP_000537055.1 LemA family protein -
  HKK59_RS08070 (HKK59_08095) rsmG 1609404..1610117 (+) 714 WP_000188795.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  HKK59_RS08075 (HKK59_08100) - 1610132..1611511 (+) 1380 WP_000680112.1 TrkH family potassium uptake protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26559.61 Da        Isoelectric Point: 4.8094

>NTDB_id=442206 HKK59_RS08050 WP_000516680.1 1606249..1606938(-) (covR) [Streptococcus agalactiae strain 01173]
MGKKILIIEDEKNLARFVSLELLHEGYDVVVETNGREGLDTALEKDFDLILLDLMLPEMDGFEITRRLQAEKTTYIMMMT
ARDSVMDIVAGLDRGADDYIVKPFAIEELLARVRAIFRRQEIETKTKEKGDSGSFRDLSLNTHNRSAMRGDEEISLTKRE
FDLLNVLMINMNRVMTREELLEHVWKYDVAAETNVVDVYIRYLRGKIDIPGRESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=442206 HKK59_RS08050 WP_000516680.1 1606249..1606938(-) (covR) [Streptococcus agalactiae strain 01173]
ATGGGTAAAAAGATCTTAATAATCGAAGATGAGAAAAATTTAGCTCGCTTCGTCTCGTTAGAACTACTACATGAAGGATA
TGATGTTGTTGTTGAAACAAACGGTCGTGAAGGATTGGACACAGCATTAGAAAAAGATTTTGATTTGATTCTACTGGATT
TAATGCTTCCAGAGATGGATGGTTTCGAAATCACACGTCGCCTGCAGGCTGAAAAAACAACCTATATCATGATGATGACA
GCACGTGATTCTGTTATGGATATTGTAGCTGGTCTTGATCGTGGAGCAGATGATTATATTGTTAAGCCGTTTGCAATCGA
AGAATTATTAGCACGTGTTAGAGCGATTTTCCGACGCCAAGAAATTGAAACGAAGACAAAAGAAAAAGGTGATAGTGGTA
GTTTCCGTGATTTGTCATTAAATACTCATAATCGTTCAGCGATGCGTGGTGATGAGGAAATTTCACTAACAAAACGTGAA
TTTGATTTGTTGAATGTCTTGATGATAAATATGAATCGTGTTATGACACGAGAAGAGTTGCTAGAACATGTTTGGAAATA
CGATGTGGCAGCAGAGACAAACGTTGTTGATGTTTATATCCGTTACCTAAGAGGTAAAATTGATATCCCAGGTCGTGAAT
CATATATTCAAACTGTTCGCGGAATGGGCTATGTGATTCGTGAAAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

79.476

100

0.795
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.228

99.563

0.659
  vicR Streptococcus mutans UA159

45.455

100

0.459
  micA Streptococcus pneumoniae Cp1015

43.478

100

0.437