Detailed information NTG0442041

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: HKJ34_RS03945
• Genome accession: NZ_CP052936
• Coordinates: 811136..813328 (+)
• Length: 730 a.a.
• NCBI ID: WP_273646900.1
• Uniprot ID: -
• Organism: Lacticaseibacillus paracasei strain CLP-C10
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 806136..818328

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HKJ34_RS03915 (HKJ34_03990)	-	806620..806817 (+)	198	WP_016383118.1	hypothetical protein	-
HKJ34_RS03920 (HKJ34_03995)	-	807179..807985 (-)	807	WP_003567351.1	LytR/AlgR family response regulator transcription factor	-
HKJ34_RS03925 (HKJ34_04000)	-	807990..808607 (-)	618	Protein_774	GHKL domain-containing protein	-
HKJ34_RS03930 (HKJ34_04005)	-	808720..809640 (+)	921	WP_003574021.1	IS30 family transposase	-
HKJ34_RS03935 (HKJ34_04010)	-	809642..810343 (-)	702	Protein_776	histidine kinase	-
HKJ34_RS03940 (HKJ34_04015)	-	810533..810670 (+)	138	WP_003571414.1	bacteriocin-like peptide, LSEI_2386 family	-
HKJ34_RS03945 (HKJ34_04020)	comA	811136..813328 (+)	2193	WP_273646900.1	peptide cleavage/export ABC transporter	Regulator
HKJ34_RS03950 (HKJ34_04025)	-	813339..814718 (+)	1380	WP_003585563.1	bacteriocin secretion accessory protein	-
HKJ34_RS03955 (HKJ34_04030)	-	814892..815242 (+)	351	WP_003567340.1	hypothetical protein	-
HKJ34_RS03960 (HKJ34_04035)	-	815315..815626 (+)	312	WP_003580849.1	hypothetical protein	-
HKJ34_RS03965 (HKJ34_04040)	-	815932..817287 (+)	1356	WP_003567335.1	threonine/serine ThrE exporter family protein	-
HKJ34_RS03970 (HKJ34_04045)	-	817389..817685 (+)	297	WP_003580847.1	bacteriocin immunity protein	-
HKJ34_RS03975 (HKJ34_04050)	-	817878..818162 (+)	285	WP_003580845.1	bacteriocin immunity protein	-

Sequence

Protein

• Length: 730 a.a.
• Molecular weight: 81372.68 Da
• Isoelectric Point: 7.2444

>NTDB_id=442041 HKJ34_RS03945 WP_273646900.1 811136..813328(+) (comA) [Lacticaseibacillus paracasei strain CLP-C10]
MIKYNLKLGQAQYYKRYYTPQVDERDCGVAALNMLLQFNGSDYSLAHLRQLAKTDQEGTTALGIVRAAQALHFETKAVKA
DMTLFDLDDVPYPFLVHVLKRGELLHYYVVFKATKDHILIGDPDPSVAMTWLPKERFAKEWSGVAIFIAPEPQYQPRKED
KGSLFAFVPILARQKGIIANIIVAAVLITLISIVGSYFLQSIIDTYIPNGMRTTLGMIASGLILAYVLQSVLTYGQNFLM
AVLGQRLSIDVILGYVRHLYELPMSFFSTRRTGEIVSRFSDANKIIDALANTIMTLFLDIWIVLILGIVLGIQNTTLFLV
SLIAVPCYLVIVFAFQRPFNRLNQETMESNAILSSSIIEDLNGIETIKSLTGEKVSYERVDREFVTYLKKSFNYTKADQL
QQAIKGLLKLVLNVVVLWIGASLVMANKMSLGQMLTFNALLAYFTNPLESIINLQPKLQMAKVANNRLNEVYLVESEFKE
QRSLNDRHLIDGAINVTDVSFKYGFGQDVLKQINLEIPENAKYTIVGMSGSGKSTLAKLLVGFYPVDTGKGKITFNGVPI
SDVDLTTLRQYIEYVPQDPFIFSGSVIENLTLGSRSNITEADIEAACSVAEIAVYISNLPQIWQTKLSESGSILSGGQKQ
RLAIARALLSPAKVLIFDESTSSLDTITERKIVDRLLAMTDRTIIFVAHRLTIAAKTEQIVVMDHGAIVEQGNHAELLAK
QGYYARLVSE

Nucleotide

• Length: 2193 bp

>NTDB_id=442041 HKJ34_RS03945 WP_273646900.1 811136..813328(+) (comA) [Lacticaseibacillus paracasei strain CLP-C10]
ATGATCAAATACAACCTAAAGCTCGGCCAAGCACAGTATTACAAGCGTTACTACACGCCTCAGGTGGATGAGCGCGATTG
CGGGGTTGCGGCGCTTAATATGTTGCTGCAATTTAATGGCTCGGATTATTCGCTAGCGCATCTGCGACAGTTGGCGAAGA
CGGATCAGGAAGGGACGACGGCATTAGGGATTGTCCGCGCTGCTCAGGCGCTTCATTTTGAAACCAAGGCGGTCAAGGCG
GATATGACGCTGTTTGATCTTGATGATGTTCCTTATCCGTTTCTTGTCCATGTTTTGAAGCGTGGCGAGTTGCTTCATTA
TTATGTGGTGTTTAAGGCGACAAAGGATCATATCTTGATTGGCGATCCTGATCCATCAGTAGCGATGACCTGGCTTCCCA
AAGAGCGCTTTGCGAAGGAGTGGTCGGGGGTCGCTATTTTTATTGCGCCAGAACCGCAATATCAACCACGCAAAGAGGAC
AAAGGCAGTCTCTTTGCGTTTGTGCCGATACTAGCGCGACAAAAAGGGATCATTGCCAATATTATTGTCGCCGCTGTGTT
GATTACGTTGATTAGTATTGTCGGGTCTTATTTTCTTCAGTCGATTATTGATACTTATATTCCAAACGGGATGCGCACAA
CTTTGGGAATGATTGCCAGTGGTCTCATCCTTGCTTATGTCCTGCAGTCGGTTTTAACCTATGGGCAAAATTTTTTGATG
GCTGTTTTAGGACAGCGTTTGTCGATTGATGTCATTTTGGGTTACGTTAGGCATCTTTATGAATTACCGATGTCCTTCTT
TTCCACGCGTCGGACTGGGGAGATTGTATCGCGGTTTTCCGATGCTAATAAGATTATTGATGCGCTGGCAAACACAATTA
TGACCTTGTTTCTTGATATTTGGATTGTCTTAATTTTAGGGATCGTGTTAGGCATTCAAAACACCACCTTATTCTTGGTG
TCTTTAATTGCTGTGCCTTGTTATTTGGTGATTGTGTTCGCTTTTCAGCGGCCATTTAATCGACTGAATCAAGAGACGAT
GGAAAGCAATGCCATATTGAGTTCATCCATTATCGAGGATTTGAACGGGATTGAGACGATTAAATCACTGACCGGTGAGA
AAGTCAGTTATGAACGGGTTGACCGTGAATTCGTCACGTATTTGAAAAAGTCGTTCAATTATACAAAAGCTGATCAACTG
CAGCAGGCGATCAAGGGACTGCTGAAGTTGGTTTTGAATGTGGTCGTGCTGTGGATTGGTGCGAGTTTGGTGATGGCTAA
CAAGATGAGTCTAGGACAGATGCTGACGTTCAATGCGTTGTTGGCATATTTCACTAATCCGTTAGAAAGCATCATTAATT
TGCAACCAAAATTGCAAATGGCCAAAGTCGCGAATAACCGGCTGAATGAAGTGTATTTGGTTGAATCGGAGTTTAAAGAA
CAGCGAAGTTTGAATGATCGGCATTTAATTGATGGCGCTATCAACGTGACCGATGTGTCTTTTAAGTATGGTTTTGGGCA
AGATGTTTTGAAACAAATCAACCTTGAAATCCCGGAGAATGCCAAATACACCATTGTCGGCATGAGTGGATCAGGGAAAT
CGACCTTAGCCAAGTTGCTAGTAGGTTTCTATCCAGTGGACACTGGCAAAGGGAAAATCACATTTAATGGGGTTCCCATC
AGTGATGTTGATCTGACAACGTTACGACAATATATCGAGTATGTACCACAAGATCCGTTTATTTTTTCTGGCTCAGTCAT
TGAAAACTTAACGTTGGGTAGCCGTTCGAATATCACTGAAGCCGATATTGAAGCTGCCTGTTCAGTGGCGGAAATTGCCG
TATATATTTCGAATTTGCCGCAGATATGGCAGACCAAACTTTCTGAAAGCGGCAGTATTTTATCGGGTGGACAAAAGCAG
CGCCTAGCAATTGCCCGCGCGTTATTATCACCGGCAAAAGTGTTGATTTTTGATGAATCGACCAGCAGTTTAGATACGAT
CACCGAGCGAAAAATTGTTGATCGGTTGTTAGCGATGACTGATCGAACCATTATTTTTGTGGCTCATCGGCTCACTATTG
CTGCTAAAACGGAACAGATTGTGGTCATGGATCATGGTGCGATTGTTGAACAAGGAAATCATGCTGAGTTATTGGCCAAA
CAAGGCTATTATGCTCGGTTGGTAAGTGAGTGA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (16-152)

• ABC transporter transmembrane region (ABC_membrane) (180-448)

• ABC transporter (ABC_tran) (510-662)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	58.914	98.356	0.579
comA	Streptococcus pneumoniae Rx1	58.357	98.356	0.574
comA	Streptococcus pneumoniae D39	58.357	98.356	0.574
comA	Streptococcus pneumoniae R6	58.357	98.356	0.574
comA	Streptococcus mitis SK321	58.217	98.356	0.573
comA	Streptococcus pneumoniae TIGR4	57.939	98.356	0.57
comA	Streptococcus gordonii str. Challis substr. CH1	56.964	98.356	0.56
comA/nlmT	Streptococcus mutans UA159	54.848	98.904	0.542