Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   HMPREF1038_RS05070 Genome accession   NC_018630
Coordinates   935465..935929 (+) Length   154 a.a.
NCBI ID   WP_001135768.1    Uniprot ID   A4L7L7
Organism   Streptococcus pneumoniae gamPNI0373     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 930465..940929
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF1038_RS13525 - 932381..932455 (+) 75 Protein_960 dihydroxyacetone kinase subunit L -
  HMPREF1038_RS12415 (HMPREF1038_01023) dhaM 932455..932835 (+) 381 Protein_961 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
  HMPREF1038_RS05055 (HMPREF1038_01025) - 933293..934006 (+) 714 WP_001844853.1 YjjG family noncanonical pyrimidine nucleotidase -
  HMPREF1038_RS05060 (HMPREF1038_01026) - 934064..934666 (+) 603 WP_001812270.1 hypothetical protein -
  HMPREF1038_RS05065 (HMPREF1038_01027) - 934802..935455 (+) 654 WP_000401326.1 uracil-DNA glycosylase -
  HMPREF1038_RS05070 (HMPREF1038_01028) mutX 935465..935929 (+) 465 WP_001135768.1 8-oxo-dGTP diphosphatase Machinery gene
  HMPREF1038_RS05075 (HMPREF1038_01029) - 935942..937210 (+) 1269 WP_001844852.1 dihydroorotase -
  HMPREF1038_RS05080 (HMPREF1038_01030) - 937224..937484 (+) 261 WP_001105925.1 hypothetical protein -
  HMPREF1038_RS05085 (HMPREF1038_01031) pdrM 937495..938856 (+) 1362 WP_001844851.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  HMPREF1038_RS05090 (HMPREF1038_01032) - 939010..939978 (+) 969 WP_001844850.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17812.16 Da        Isoelectric Point: 4.2287

>NTDB_id=44200 HMPREF1038_RS05070 WP_001135768.1 935465..935929(+) (mutX) [Streptococcus pneumoniae gamPNI0373]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=44200 HMPREF1038_RS05070 WP_001135768.1 935465..935929(+) (mutX) [Streptococcus pneumoniae gamPNI0373]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAATGGGAAAGAATTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGGCGCGTGAAA
TCCTTGAAGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGACGCTAGAATGGGTTCC
CTATGATGAGGTTTTGAGCAAGCCGACTTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCCAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4L7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.701

100

0.987

Multiple sequence alignment