Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   HMPREF1038_RS02230 Genome accession   NC_018630
Coordinates   399408..401744 (+) Length   778 a.a.
NCBI ID   WP_001035004.1    Uniprot ID   C1CIQ8
Organism   Streptococcus pneumoniae gamPNI0373     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 394408..406744
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF1038_RS02210 (HMPREF1038_00447) lepB 396872..397486 (-) 615 WP_001048156.1 signal peptidase I -
  HMPREF1038_RS02215 (HMPREF1038_00448) rnhC 397498..398370 (-) 873 WP_000146857.1 ribonuclease HIII -
  HMPREF1038_RS02220 (HMPREF1038_00449) zapA 398457..398759 (+) 303 WP_000002019.1 cell division protein ZapA -
  HMPREF1038_RS02225 (HMPREF1038_00450) - 398756..399304 (+) 549 WP_000622954.1 CvpA family protein -
  HMPREF1038_RS02230 (HMPREF1038_00451) mutS/mutS2 399408..401744 (+) 2337 WP_001035004.1 endonuclease MutS2 Machinery gene
  HMPREF1038_RS02235 (HMPREF1038_00452) - 402087..403409 (+) 1323 WP_000891508.1 sodium:alanine symporter family protein -
  HMPREF1038_RS02240 (HMPREF1038_00453) - 403627..404175 (+) 549 WP_000206761.1 carboxymuconolactone decarboxylase family protein -
  HMPREF1038_RS02245 (HMPREF1038_00454) - 404285..405184 (+) 900 WP_000735957.1 TDT family transporter -
  HMPREF1038_RS02250 (HMPREF1038_00455) serS 405209..406483 (-) 1275 WP_000884249.1 serine--tRNA ligase -

Sequence

Protein


Download         Length: 778 a.a.        Molecular weight: 87608.56 Da        Isoelectric Point: 6.8352

>NTDB_id=44179 HMPREF1038_RS02230 WP_001035004.1 399408..401744(+) (mutS/mutS2) [Streptococcus pneumoniae gamPNI0373]
MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIKQAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEM
GADLNIEEFLLLKRVLLASRELQNFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTVYIEPREVVKLSEEIASLRADER
YEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRAKVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQD
LTAIVITGPNTGGKTIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNIVDILGKVN
QHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYGIETAFVQNASMEFDTATLRPTYRFMQGVPG
RSNAFEIAKRLGLSEVIVGDASQQIDQDNDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETE
LNKAREQAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAKKKRAPKVGDDIVVLSY
GQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPVKKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFI
DQALLNNMAQVDIIHGIGTGVIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG

Nucleotide


Download         Length: 2337 bp        

>NTDB_id=44179 HMPREF1038_RS02230 WP_001035004.1 399408..401744(+) (mutS/mutS2) [Streptococcus pneumoniae gamPNI0373]
ATGAATAAGAAAATATTAGAAACATTAGAGTTCGATAAGGTCAAGGCCTTGTTTGAGCCTCATTTGTTGACCGAGCAGGG
CTTGGAGCAATTGAGACAGCTGGCTCCGACTGCCAAAGCAGATAAAATCAAACAGGCTTTTGCTGAGATGAAAGAAATGC
AGGCTCTTTTCGTCGAGCAACCGCATTTTACTATTCTCTCAACTAAGGAAATTGCAGGAGTCTGCAAGAGGTTGGAGATG
GGAGCGGATCTCAATATCGAGGAGTTCCTACTCTTGAAACGCGTGCTTCTTGCCAGCCGAGAACTTCAAAATTTTTACGC
CAATCTGGAAAATGTCAGCTTGGAAGAATTAGCCCTTTGGTTTGAGAAATTACATGATTTTCCGCAATTACAAGGAAATC
TTCAGGCCTTTAATGATGCGGGTTTCATTGAAAATTTTGCCAGTGAAGAATTGGCGCGAATCCGTCGAAAAATACATGAT
AGCGAGAGTCAGGTGCGCGATGTTTTACAAGACTTACTCAAGCAAAAAGCGCAGATGTTGACGGAAGGAATTGTTGCTAG
CAGAAATGGCCGTCAGGTTTTACCAGTCAAAAACACCTACCGCAATAAGATTGCAGGTGTCGTTCATGATATTTCTGCTA
GTGGAAACACCGTCTATATCGAACCACGTGAGGTAGTCAAACTGAGCGAAGAAATTGCTAGTCTGCGAGCAGATGAGCGC
TATGAAATGCTTCGCATTCTCCAAGAAATTTCTGAGCGTGTCCGCCCTCATGCGGCTGAGATTGCTAATGACGCTTGGAT
TATCGGTCATCTGGACTTGATTCGTGCCAAGGTTCGATTTATCCAAGAAAGACAAGCAGTCGTGCCTCAGCTGTCAGAAA
ATCAAGAGATTCAACTGCTCCATGTCTGCCATCCTTTGGTCAAAAATGCCGTCGCAAATGATGTCTATTTTGGTCAAGAT
TTAACAGCTATTGTCATTACAGGTCCCAATACAGGTGGGAAGACCATCATGCTCAAAACTCTGGGCTTGACACAGGTCAT
GGCCCAGTCAGGATTGCCGATTTTAGCAGACAAGGGAAGTCGTGTTGGTATTTTTGAAGAAATCTTTGCTGATATTGGAG
ATGAGCAGTCTATTGAGCAGAGCTTGTCTACCTTCTCTAGCCATATGACCAATATCGTGGATATTCTTGGCAAGGTCAAC
CAACATTCACTCTTACTTTTGGATGAGTTGGGGGCTGGTACTGATCCCCAAGAGGGAGCAGCCCTTGCCATGGCTATTCT
GGAGGACCTTCGCCTGCGTCAAATCAAGACCATGGCGACGACCCACTATCCAGAACTCAAGGCCTACGGTATTGAGACAG
CCTTTGTGCAAAATGCCAGTATGGAGTTTGATACTGCAACTCTTCGCCCGACCTATCGCTTTATGCAGGGTGTTCCTGGC
CGAAGTAATGCCTTTGAAATTGCCAAACGTCTAGGCCTATCTGAAGTTATCGTAGGAGATGCCAGTCAGCAGATCGATCA
GGACAATGACGTCAATCGTATCATTGAGCAATTAGAAGAGCAGACGCTGGAAAGCCGCAAACGTTTGGACAATATCCGTG
AGGTGGAGCAAGAAAATCTCAAGATGAACCGTGCGCTAAAAAAACTCTACAACGAGCTTAATCGTGAAAAGGAAACCGAG
CTTAACAAGGCGCGTGAACAGGCTGCTGAGATTGTGGATATGGCCCTAAGTGAAAGTGACCAGATTCTCAAAAATCTCCA
CAGTAAATCCCAACTCAAGCCCCACGAAATCATTGAAGCCAAGGCCAAGTTGAAAAAATTGGCTCCTGAAAAAGTGGACT
TGTCTAAAAACAAGGTCCTTCAAAAGGCCAAGAAAAAACGAGCTCCAAAGGTGGGAGATGATATCGTGGTTCTCAGTTAT
GGTCAGCGTGGTACCTTGACCAGTCAACTCAAGGACGGCCGCTGGGAAGCCCAAGTTGGCTTGATTAAGATGACCTTGGA
AGAGAAAGAGTTTGATCTTGTTCAAGCCCAGCAAGAAAAACCAGTCAAGAAGAAACAGGTCAATGTTGTGAAACGAACTT
CTGGGCGAGGACCTCAAGCTAGACTGGATCTTCGAGGCAAGCGCTATGAAGAAGCCATGAATGAGCTAGATACCTTCATC
GACCAAGCCTTGCTTAACAATATGGCTCAAGTTGATATCATCCATGGTATCGGAACAGGAGTCATCCGTGAAGGAGTTAC
CAAATACTTGCAAAGAAACAAACATGTCAAGAGTTTCGGCTATGCCCCACAAAATGCTGGAGGCAGTGGTGCGACTATTG
TCACTTTTAAAGGATAG

Domains

Predicted by InterProScan.

MutS domain V (MutS_V)

(324-506)

Smr domain (Smr)

(702-777)

MutS2 and Smr-associated SH3 domain (MSSS)

(631-670)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C1CIQ8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

40.708

100

0.414

Multiple sequence alignment