Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   SAMSHR1132_RS09890 Genome accession   NC_016941
Coordinates   2028423..2029139 (+) Length   238 a.a.
NCBI ID   WP_000688486.1    Uniprot ID   A0A7U7PWL0
Organism   Staphylococcus argenteus     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2023423..2034139
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SAMSHR1132_RS09860 (SAMSHR1132_18550) - 2023979..2024605 (+) 627 WP_000522390.1 nitroreductase family protein -
  SAMSHR1132_RS09865 (SAMSHR1132_18560) - 2024706..2025491 (+) 786 WP_000867961.1 carbon-nitrogen family hydrolase -
  SAMSHR1132_RS14455 hld 2026012..2026092 (-) 81 WP_000046023.1 delta-hemolysin -
  SAMSHR1132_RS09875 (SAMSHR1132_18580) - 2026382..2026945 (+) 564 WP_001105703.1 accessory gene regulator AgrB -
  SAMSHR1132_RS09880 (SAMSHR1132_18590) agrD 2026947..2027087 (+) 141 WP_001093930.1 cyclic lactone autoinducer peptide AgrD -
  SAMSHR1132_RS09885 (SAMSHR1132_18600) agrC 2027112..2028404 (+) 1293 WP_000420350.1 quorum-sensing sensor histidine kinase AgrC -
  SAMSHR1132_RS09890 (SAMSHR1132_18610) agrA 2028423..2029139 (+) 717 WP_000688486.1 quorum-sensing response regulator AgrA Regulator
  SAMSHR1132_RS09895 (SAMSHR1132_18620) - 2029492..2030451 (-) 960 WP_001253278.1 carbohydrate kinase -
  SAMSHR1132_RS09900 (SAMSHR1132_18630) - 2030448..2031932 (-) 1485 WP_000141408.1 sucrose-6-phosphate hydrolase -
  SAMSHR1132_RS09905 (SAMSHR1132_18640) - 2032081..2033031 (-) 951 WP_000790316.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27894.87 Da        Isoelectric Point: 5.8625

>NTDB_id=44173 SAMSHR1132_RS09890 WP_000688486.1 2028423..2029139(+) (agrA) [Staphylococcus argenteus]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDDPYEVLEQSKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELKTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=44173 SAMSHR1132_RS09890 WP_000688486.1 2028423..2029139(+) (agrA) [Staphylococcus argenteus]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAACCTATGGAAATTGCCCTCGCAACTGATGATCCTTATGAGGTGCTTGAGCAATCTAAAAATATGAATGATATAG
GTTGTTACTTTTTAGATATTCAACTTTCAACAGACATTAATGGTATTAAATTAGGTAGTGAAATACGTAAGCATGACCCT
GTTGGCAATATAATATTTGTTACTAGTCATAGTGAACTTACTTATTTAACATTTGTCTACAAAGTTGCAGCAATGGATTT
TATTTTTAAAGATGATCCTGCTGAATTAAAAACACGAATTATAGATTGTCTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATAGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATACGATGATATTATG
TTTTTCGAATCATCTACCAAATCGCATAGACTCATCGCCCATTTAGATAATCGTCAAATTGAATTTTATGGTAATTTAAA
AGAATTGAGTCAATTAGATGATCGTTTTTTCAGATGTCATAATAGTTTTGTTGTCAATCGTCATAATATCGAATCCATTG
ATTCGAAAGAACGAATTGTCTATTTTAAAAATAAAGAACATTGTTATGCATCGGTAAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7PWL0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

98.739

100

0.987

Multiple sequence alignment