Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsR   Type   Regulator
Locus tag   HMPREF1038_RS01150 Genome accession   NC_018630
Coordinates   195281..195721 (-) Length   146 a.a.
NCBI ID   WP_000861968.1    Uniprot ID   -
Organism   Streptococcus pneumoniae gamPNI0373     
Function   antagonizing the proteolysis of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 190281..200721
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF1038_RS01125 (HMPREF1038_00230) - 190542..191828 (+) 1287 WP_000278864.1 response regulator transcription factor -
  HMPREF1038_RS01130 (HMPREF1038_00231) - 191880..192413 (+) 534 WP_000729037.1 hypothetical protein -
  HMPREF1038_RS01135 (HMPREF1038_00232) nrdI 192491..192961 (+) 471 WP_000849618.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  HMPREF1038_RS01140 (HMPREF1038_00233) - 193254..194516 (-) 1263 WP_000075789.1 NRAMP family divalent metal transporter -
  HMPREF1038_RS01145 (HMPREF1038_00234) - 194826..195284 (-) 459 WP_000745054.1 DUF3021 domain-containing protein -
  HMPREF1038_RS01150 (HMPREF1038_00235) brsR 195281..195721 (-) 441 WP_000861968.1 LytTR family DNA-binding domain-containing protein Regulator
  HMPREF1038_RS01155 (HMPREF1038_00236) hexB 195927..197876 (+) 1950 WP_000018164.1 DNA mismatch repair endonuclease MutL Machinery gene
  HMPREF1038_RS01160 (HMPREF1038_00238) ribE 198201..198668 (-) 468 WP_001099502.1 6,7-dimethyl-8-ribityllumazine synthase -
  HMPREF1038_RS01165 (HMPREF1038_00239) - 198669..199874 (-) 1206 WP_000456639.1 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II -
  HMPREF1038_RS01170 (HMPREF1038_00240) ribE 199894..200529 (-) 636 WP_000493842.1 riboflavin synthase -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17137.81 Da        Isoelectric Point: 5.9797

>NTDB_id=44167 HMPREF1038_RS01150 WP_000861968.1 195281..195721(-) (brsR) [Streptococcus pneumoniae gamPNI0373]
MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIKGKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSI
DLRLYQVLKLLPTNFIQISQSEIINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL

Nucleotide


Download         Length: 441 bp        

>NTDB_id=44167 HMPREF1038_RS01150 WP_000861968.1 195281..195721(-) (brsR) [Streptococcus pneumoniae gamPNI0373]
ATGAAAGTAGAACTACAGATTAGTGAGACTTACGAGGAGGAAAAGCTGATTGTCCAAGCACCTCAGCCGACAGATAAAGT
CCAGAAAGTCATCGAGTTCGCAGAAAATCTGGACCAAAGAGAAAAAATCAAAGGGAAAATCGATGATCAGGTCTATCTAG
TTGAGATTGGCAAGATTCAGCGCTTCTATATCGAGAATCGGAAGGTTCTAGCAGAAACCGCGAGTCAGACCTACAGCATT
GATTTGCGACTCTATCAGGTTCTTAAACTCTTGCCAACCAATTTTATCCAAATTTCCCAATCAGAAATCATCAATATCGA
TTCCATCTCTCACCTCAAGCTCACGCCAAACGGTCTGGTAGAAATTTTCTTGAAAAACGAAAGCTTCACCTACTCTTCAC
GCCGTTATCTAAAAACCATCAAGGAGAAATTAGAACTATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(50-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsR Streptococcus mutans UA159

36.054

100

0.363

Multiple sequence alignment