Detailed information NTG0441493

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: IPZ77_RS16200
• Genome accession: NZ_CP064057
• Coordinates: 3567112..3568266 (-)
• Length: 384 a.a.
• NCBI ID: WP_030734901.1
• Uniprot ID: A0A0F7FUX4
• Organism: Streptomyces sp. XC 2026
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3562112..3573266

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IPZ77_RS16180 (IPZ77_16185)	-	3562930..3563592 (+)	663	WP_200366362.1	response regulator transcription factor	-
IPZ77_RS16185 (IPZ77_16190)	-	3563604..3564866 (+)	1263	WP_200366363.1	HAMP domain-containing sensor histidine kinase	-
IPZ77_RS16190 (IPZ77_16195)	-	3564912..3565823 (-)	912	WP_200366364.1	A/G-specific adenine glycosylase	-
IPZ77_RS16195 (IPZ77_16200)	-	3565975..3566823 (+)	849	WP_200366365.1	hypothetical protein	-
IPZ77_RS16200 (IPZ77_16205)	disA	3567112..3568266 (-)	1155	WP_030734901.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
IPZ77_RS16205 (IPZ77_16210)	radA/sms	3568307..3569752 (-)	1446	WP_200366367.1	DNA repair protein RadA	Machinery gene
IPZ77_RS27625 (IPZ77_16215)	-	3569870..3571582 (+)	1713	WP_200366368.1	sigma-70 family RNA polymerase sigma factor	-
IPZ77_RS16215 (IPZ77_16220)	-	3571633..3572343 (-)	711	WP_200366369.1	TetR family transcriptional regulator	-
IPZ77_RS16220 (IPZ77_16225)	-	3572333..3573163 (-)	831	WP_200366370.1	sugar phosphate isomerase/epimerase	-

Sequence

Protein

• Length: 384 a.a.
• Molecular weight: 40872.72 Da
• Isoelectric Point: 5.3601

>NTDB_id=441493 IPZ77_RS16200 WP_030734901.1 3567112..3568266(-) (disA) [Streptomyces sp. XC 2026]
MAANDRPAGPGRAGGAGGGSGADGLLRASLSAVAPGTQLRDGLERILRGNTGGLIVLGVDRTVESLCTGGFVLDVEFTAT
RLRELCKLDGAVIVDRDITKIVRAGVQLVPDASIPTEETGTRHRTAQRVSIQTGFPVVSVSQSMRLIALYLDGQRRVLED
SGAILSRANQALATLERYKLRFDEVAGTLSALEIEDLVTVRDVAAVAQRLEMVRRIAAEIAEYVVELGTDGRLLSLQLDE
LIAGVEPERQLIVRDYLPESPQGTEPPGGKRSRRVGTALSELDALTHAELLELPIVARALGHGASPEALDGAVSPRGFRL
LAKVPRLPGLVIDRLVDHFGGLQKLLAASVDDLQAVDGVGETRARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1155 bp

>NTDB_id=441493 IPZ77_RS16200 WP_030734901.1 3567112..3568266(-) (disA) [Streptomyces sp. XC 2026]
ATGGCAGCCAACGACCGGCCGGCGGGTCCCGGCAGGGCCGGGGGTGCCGGGGGAGGTTCCGGAGCGGACGGACTGCTGCG
CGCCTCGCTGAGCGCGGTGGCCCCCGGAACCCAGCTGCGGGACGGCCTGGAGCGCATCCTGCGGGGCAACACGGGCGGCC
TGATCGTCCTCGGCGTGGACCGTACCGTCGAATCCCTGTGCACCGGCGGTTTCGTGCTGGACGTGGAGTTCACCGCGACC
CGGCTGCGCGAGCTGTGCAAGCTGGACGGCGCGGTGATCGTGGACCGCGACATCACCAAGATCGTCCGCGCGGGCGTGCA
GTTGGTCCCGGACGCGAGCATCCCGACCGAGGAGACCGGCACCCGGCACCGTACGGCGCAGCGGGTCTCCATCCAGACCG
GGTTCCCCGTGGTGTCGGTCAGCCAGTCGATGCGGCTGATCGCCCTGTACCTGGACGGGCAGCGGCGGGTCCTGGAGGAC
TCGGGCGCCATCCTGTCCCGGGCGAACCAGGCGCTGGCCACCCTGGAGCGGTACAAGCTGCGGTTCGACGAGGTCGCGGG
CACCCTGTCGGCGCTGGAGATCGAGGACCTGGTCACGGTCCGCGACGTGGCGGCGGTGGCGCAGCGGCTGGAGATGGTGC
GCCGGATCGCGGCCGAGATCGCCGAGTACGTGGTGGAGCTGGGCACGGACGGGCGGCTGCTGTCGCTCCAGCTGGACGAG
CTGATCGCGGGTGTGGAGCCGGAACGGCAGCTGATCGTGCGCGACTACCTGCCGGAATCGCCGCAGGGCACGGAGCCCCC
GGGCGGCAAGCGTTCGCGCCGGGTGGGCACGGCGCTGTCCGAGCTCGACGCGCTGACCCACGCCGAGCTGCTGGAACTGC
CCATCGTGGCGCGGGCGCTGGGCCACGGCGCCTCGCCCGAGGCGCTGGACGGCGCGGTCTCCCCGCGGGGTTTCCGGCTG
CTGGCGAAGGTCCCGCGGCTGCCGGGTCTGGTCATCGACCGGCTCGTGGACCACTTCGGCGGGTTGCAGAAGCTGCTGGC
GGCGAGTGTGGACGACCTGCAGGCGGTGGACGGCGTCGGAGAGACCCGGGCGCGCTCGGTGCGCGAGGGCCTGTCCCGGC
TGGCCGAGTCCTCGATCCTGGAACGGTACGTGTAG

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (41-154)

• Helix-hairpin-helix motif (HHH_2) (334-369)

• DisA bacterial checkpoint controller linker region (DisA-linker) (158-307)

3D structure

• AlphaFold DB: A0A0F7FUX4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	44.258	92.969	0.411