Detailed information NTG0044007

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SAVC_RS13155
• Genome accession: NC_016912
• Coordinates: 2588906..2589793 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus subsp. aureus VC40
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2583906..2594793

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAVC_RS13120	-	2583925..2584017 (+)	93	WP_010956583.1	hypothetical protein	-
SAVC_RS13125 (SAVC_11970)	-	2584125..2584622 (-)	498	WP_001065268.1	glutathione peroxidase	-
SAVC_RS13130 (SAVC_11975)	-	2584632..2584892 (-)	261	WP_001789910.1	hypothetical protein	-
SAVC_RS13135	-	2585274..2585387 (-)	114	WP_011447078.1	hypothetical protein	-
SAVC_RS13145 (SAVC_11980)	-	2586046..2588046 (-)	2001	WP_000776751.1	ABC transporter permease	-
SAVC_RS13150 (SAVC_11985)	-	2588043..2588798 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
SAVC_RS13155 (SAVC_11990)	braS	2588906..2589793 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SAVC_RS13160	nsaR	2589804..2590470 (-)	667	Protein_2478	nisin susceptibility-associated two-component system response regulator NsaR	-
SAVC_RS13165 (SAVC_12005)	-	2590496..2590696 (-)	201	WP_000604728.1	hypothetical protein	-
SAVC_RS13175 (SAVC_12010)	-	2590894..2592318 (+)	1425	WP_000953744.1	alkaline phosphatase	-
SAVC_RS14615 (SAVC_12015)	-	2592378..2592479 (-)	102	WP_000731972.1	SE2200 family small protein	-
SAVC_RS13180 (SAVC_12020)	-	2592601..2593056 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
SAVC_RS13185 (SAVC_12025)	-	2593301..2594062 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=44007 SAVC_RS13155 WP_000143419.1 2588906..2589793(-) (braS) [Staphylococcus aureus subsp. aureus VC40]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=44007 SAVC_RS13155 WP_000143419.1 2588906..2589793(-) (braS) [Staphylococcus aureus subsp. aureus VC40]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997