Detailed information NTG0439906

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: HHM65_RS07620
• Genome accession: NZ_CP051624
• Coordinates: 1523370..1524407 (-)
• Length: 345 a.a.
• NCBI ID: WP_015057897.1
• Uniprot ID: A0A9X9R3T4
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A74
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1518370..1529407

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HHM65_RS07595 (HHM65_07600)	rbsC	1518394..1519335 (-)	942	WP_022554979.1	hypothetical protein	-
HHM65_RS07600 (HHM65_07605)	-	1519337..1520815 (-)	1479	WP_015057896.1	sugar ABC transporter ATP-binding protein	-
HHM65_RS07605 (HHM65_07610)	rbsD	1520831..1521229 (-)	399	WP_003051896.1	D-ribose pyranase	-
HHM65_RS07610 (HHM65_07615)	rbsK	1521204..1522115 (-)	912	WP_003061715.1	ribokinase	-
HHM65_RS07615 (HHM65_07620)	-	1522108..1523091 (-)	984	WP_003053684.1	LacI family DNA-binding transcriptional regulator	-
HHM65_RS07620 (HHM65_07625)	sepM	1523370..1524407 (-)	1038	WP_015057897.1	SepM family pheromone-processing serine protease	Regulator
HHM65_RS07625 (HHM65_07630)	coaD	1524394..1524885 (-)	492	WP_003051905.1	pantetheine-phosphate adenylyltransferase	-
HHM65_RS07630 (HHM65_07635)	rsmD	1524875..1525414 (-)	540	WP_041781651.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
HHM65_RS07635 (HHM65_07640)	asnA	1525608..1526600 (-)	993	WP_003061055.1	aspartate--ammonia ligase	-
HHM65_RS07640 (HHM65_07645)	arcC	1526927..1527877 (-)	951	WP_015057899.1	carbamate kinase	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37589.15 Da
• Isoelectric Point: 9.4270

>NTDB_id=439906 HHM65_RS07620 WP_015057897.1 1523370..1524407(-) (sepM) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A74]
MKTIKKIKWWLISLIALVALLIVLFFPLPYYVEMPGGAYDIRSVVKVNGKEDKDKGSYQFVAVSLSRASLAQLLYAWLTP
FTEISSVEDTTGGYSDADYIRINQFYMETSQNAAVYQALTLADKPVTLDYKGVYVLDISKDSTFKGTLNLADTVTGVNHK
QFTSSTELVDYVSHLKLGDKVTVQFISNSEPKSETGRIIKLKNGKNGIGIALTDHTKVNSADKIEFSTQGVGGPSAGLMF
TLDIYDQINKEDLRKGRHIAGTGTIGKDGEVGDIGGAGLKVVAAADAGAEIFFVPNNPVDKAVKKANPKAISNYEEAKRA
AKQLKTKMKIVPVTTVQDALAYLRQ

Nucleotide

• Length: 1038 bp

>NTDB_id=439906 HHM65_RS07620 WP_015057897.1 1523370..1524407(-) (sepM) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A74]
ATGAAAACAATTAAAAAAATTAAATGGTGGCTGATTAGTCTAATTGCCCTCGTGGCTCTGCTTATCGTCCTTTTTTTCCC
TCTTCCTTATTATGTTGAAATGCCTGGCGGAGCCTATGACATTCGATCTGTGGTCAAGGTTAATGGCAAAGAAGATAAAG
ATAAAGGCTCCTATCAGTTTGTGGCAGTCAGTCTCAGTCGAGCCAGTTTAGCTCAGTTGCTCTATGCTTGGCTAACCCCT
TTTACTGAAATCAGTTCAGTTGAGGATACCACAGGCGGTTATAGCGATGCAGACTATATCCGCATTAATCAATTCTACAT
GGAAACCTCACAAAATGCTGCGGTCTATCAGGCATTGACCTTGGCAGACAAACCAGTTACTTTGGACTACAAAGGGGTAT
ATGTGTTAGATATTAGCAAGGATTCAACCTTTAAAGGTACTTTAAACTTAGCAGATACGGTAACGGGAGTGAATCACAAA
CAATTTACGAGTTCAACAGAACTTGTGGACTATGTCTCTCATTTAAAACTTGGTGATAAGGTGACTGTGCAGTTTATTAG
TAATAGCGAACCTAAGTCTGAAACAGGTCGTATCATCAAACTAAAAAATGGTAAAAATGGTATCGGCATTGCTTTAACAG
ACCATACTAAAGTCAATTCAGCAGACAAAATCGAGTTTAGTACCCAAGGTGTTGGGGGTCCTAGCGCAGGCTTAATGTTT
ACATTAGATATCTACGACCAAATTAATAAAGAAGACCTTCGTAAAGGAAGACATATCGCCGGGACAGGAACCATTGGTAA
AGATGGTGAAGTTGGAGATATTGGCGGTGCGGGTCTTAAGGTCGTTGCTGCTGCAGATGCTGGTGCTGAGATTTTCTTTG
TGCCGAATAATCCTGTGGATAAAGCTGTTAAAAAAGCCAATCCAAAAGCTATTAGCAATTATGAAGAGGCCAAGCGAGCA
GCCAAGCAGTTAAAAACAAAAATGAAAATTGTTCCTGTAACAACTGTTCAGGATGCCCTAGCCTACCTTCGTCAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-192)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-299)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	71.884	100	0.719