Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   HHM65_RS00815 Genome accession   NZ_CP051624
Coordinates   130797..131750 (+) Length   317 a.a.
NCBI ID   WP_003060701.1    Uniprot ID   A0A9X8T146
Organism   Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A74     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 125797..136750
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HHM65_RS00775 (HHM65_00780) - 126623..126988 (+) 366 WP_003055257.1 DUF1033 family protein -
  HHM65_RS00780 (HHM65_00785) comGA/cglA 127069..128010 (+) 942 WP_170078124.1 competence type IV pilus ATPase ComGA Machinery gene
  HHM65_RS00785 (HHM65_00790) comYB 127946..128977 (+) 1032 WP_015057201.1 competence type IV pilus assembly protein ComGB Machinery gene
  HHM65_RS00790 (HHM65_00795) comYC 128979..129305 (+) 327 WP_003055259.1 competence type IV pilus major pilin ComGC Machinery gene
  HHM65_RS00795 (HHM65_00800) comGD 129280..129708 (+) 429 WP_041781473.1 competence type IV pilus minor pilin ComGD -
  HHM65_RS00800 (HHM65_00805) comGE 129716..129961 (+) 246 WP_003058569.1 competence type IV pilus minor pilin ComGE -
  HHM65_RS00805 (HHM65_00810) comGF 129942..130382 (+) 441 WP_170078125.1 competence type IV pilus minor pilin ComGF -
  HHM65_RS00810 (HHM65_00815) comGG 130405..130734 (+) 330 WP_003058539.1 competence type IV pilus minor pilin ComGG -
  HHM65_RS00815 (HHM65_00820) comYH 130797..131750 (+) 954 WP_003060701.1 class I SAM-dependent methyltransferase Machinery gene
  HHM65_RS00820 (HHM65_00825) - 131809..133005 (+) 1197 WP_015057203.1 acetate kinase -
  HHM65_RS00825 (HHM65_00830) - 133311..133517 (+) 207 WP_003058508.1 helix-turn-helix transcriptional regulator -
  HHM65_RS00830 (HHM65_00835) - 133620..134300 (+) 681 WP_012766451.1 type II CAAX endopeptidase family protein -
  HHM65_RS00835 (HHM65_00840) - 134318..134755 (+) 438 WP_012766452.1 hypothetical protein -
  HHM65_RS00840 (HHM65_00845) proC 134894..135670 (-) 777 WP_014611934.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 36049.01 Da        Isoelectric Point: 4.7910

>NTDB_id=439871 HHM65_RS00815 WP_003060701.1 130797..131750(+) (comYH) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A74]
MNFEKIEEAYQLLLENSQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNINKLKALHLTKEEWRRAYQFIFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKKLDYVGIELDDLLIDLSASIAEVMDSS
ARFIQEDAVRPQLLKESDVVISDLPVGYYPNDDIAKRYKVASSEEHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSSQ
SQLLKNWLTGYAQVVALITLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMQNFKKWKQDNVN

Nucleotide


Download         Length: 954 bp        

>NTDB_id=439871 HHM65_RS00815 WP_003060701.1 130797..131750(+) (comYH) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A74]
ATGAATTTTGAAAAAATTGAAGAAGCCTATCAGTTACTTTTAGAGAATAGTCAACTGATTGAAAATGATCTAAAAACACA
TATTTATGATGCCATCGTTGAGCAAAACTCTTTTTATTTAGGTGCTGAGGGAGCTAGTCCTCAAGTTGCCCAGAATATTA
ACAAACTGAAAGCCTTACACCTGACTAAAGAAGAATGGCGGAGAGCTTACCAGTTTATTTTTATTAAGGCAGCTCAGACT
GAGCAGCTCCAAGCAAACCATCAGTTCACGCCAGATGCTATTGGTTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
CAAAGATAGCCTAGAAGTCCTTGAAATTGGCAGTGGTACGGGAAATCTAGCACAAACTCTCCTCAATAATACGAGTAAGA
AACTTGATTATGTAGGAATTGAACTTGACGACCTCTTAATTGATTTATCAGCAAGTATTGCTGAAGTAATGGACTCTTCA
GCTCGTTTTATTCAAGAAGATGCTGTAAGACCGCAATTGTTAAAAGAAAGCGATGTTGTTATCAGTGACTTGCCAGTGGG
TTATTATCCTAATGATGACATTGCTAAGCGCTATAAGGTAGCTAGTTCTGAGGAACACACCTATGCTCATCATTTACTCA
TGGAACAATCTTTAAAGTATTTGAAAAAAGATGGTTTTGCCATTTTCTTGGCACCTGTCAATTTGTTGACAAGCTCTCAG
AGCCAATTGTTGAAAAATTGGTTAACTGGCTATGCCCAGGTAGTGGCCTTGATTACTCTACCAGATTCTATATTTGGTCA
TCCCTCTAATGCTAAGTCCATTATTGTCTTGCAAAAGCAGACAGACCATCCGATGGAAACCTTTGTTTATCCTATTCGAG
ACTTGAAGCTTGCAGAGAATATTCATGACTTTATGCAAAATTTCAAAAAATGGAAACAGGATAATGTCAATTAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(68-289)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

66.456

99.685

0.662
  comYH Streptococcus mutans UA159

66.139

99.685

0.659