Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   HG697_RS07220 Genome accession   NZ_CP051623
Coordinates   1444062..1446353 (+) Length   763 a.a.
NCBI ID   WP_015057878.1    Uniprot ID   A0AB33R6E6
Organism   Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A19     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1439062..1451353
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HG697_RS07195 (HG697_07200) feoB 1439152..1441311 (-) 2160 WP_015057877.1 ferrous iron transport protein B -
  HG697_RS07200 (HG697_07205) - 1441308..1441787 (-) 480 WP_003056958.1 ferrous iron transport protein A -
  HG697_RS07205 (HG697_07210) - 1441986..1442720 (-) 735 WP_003061973.1 amino acid ABC transporter ATP-binding protein -
  HG697_RS07210 (HG697_07215) - 1442720..1443406 (-) 687 WP_003051835.1 amino acid ABC transporter permease -
  HG697_RS07215 (HG697_07220) - 1443534..1443764 (-) 231 WP_003051836.1 DUF1797 family protein -
  HG697_RS07220 (HG697_07225) clpE 1444062..1446353 (+) 2292 WP_015057878.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  HG697_RS07225 (HG697_07230) - 1446471..1446926 (+) 456 WP_003059823.1 NUDIX hydrolase -
  HG697_RS07230 (HG697_07235) - 1446976..1447278 (+) 303 WP_003051842.1 DUF1827 family protein -
  HG697_RS07235 (HG697_07240) ileS 1447681..1450482 (-) 2802 WP_015057879.1 isoleucine--tRNA ligase -

Sequence

Protein


Download         Length: 763 a.a.        Molecular weight: 84941.24 Da        Isoelectric Point: 5.3453

>NTDB_id=439845 HG697_RS07220 WP_015057878.1 1444062..1446353(+) (clpE) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A19]
MLCQNCNLNESTIHLYTNVNGKQKQVDLCQNCYQIMKTDPTNPILGGLNGGQRAQERSSNPFFDDFFGDLNNFRAFGNLP
NTPPTQAGQNGNGGGRHGGHFNGQRPTQPQTPNQQAKGLLEEFGINVTDIARHGDIDPVIGRDDEITRVIEILNRRTKNN
PVLIGEPGVGKTAVVEGLAQKIVDGTVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRKDVILFIDEIHE
IVGAGSAGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHH
VKYSPAAIEAAAHLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDKRLIEAENLKAQATRDEDYERAAYFRDQ
IAKYKEMQAQKVDEQDIPIITEKTIEAIIEQKTNIPVGDLKEKEQSQLVNLANDLKAHVIGQDDAVDKIAKAIRRNRVGL
GTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPY
SLILLDEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKSEASVGFGAAREGRTSSVLGELSNFFS
PEFMNRFDGIIEFKALSKDNLLHIVDLMLEDVNKRLGYNGIHLDVTQKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAIT
DYYLEHPTEKDLRAIMTSNSNIMIKAAKKDETVTAKQDKTDEN

Nucleotide


Download         Length: 2292 bp        

>NTDB_id=439845 HG697_RS07220 WP_015057878.1 1444062..1446353(+) (clpE) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A19]
ATGCTTTGTCAAAATTGTAATTTAAACGAATCAACCATTCACCTCTACACGAATGTTAATGGAAAACAAAAACAAGTTGA
CCTTTGTCAAAACTGTTATCAAATCATGAAGACTGACCCTACTAATCCTATTTTAGGTGGCCTAAATGGAGGTCAAAGAG
CCCAAGAACGCTCATCCAACCCCTTCTTTGATGACTTTTTTGGGGACTTAAATAATTTTAGGGCCTTCGGTAACCTTCCA
AATACCCCACCTACTCAGGCAGGGCAAAATGGAAATGGTGGGGGACGCCATGGTGGTCATTTCAATGGGCAACGTCCCAC
TCAGCCACAAACACCAAATCAGCAAGCAAAAGGCTTGCTAGAAGAATTTGGCATTAATGTGACCGATATTGCAAGACATG
GTGATATTGACCCTGTCATCGGTCGAGATGACGAGATTACACGTGTCATCGAAATCCTTAACCGTCGGACTAAAAATAAC
CCTGTGCTTATTGGGGAACCAGGAGTTGGTAAAACAGCTGTTGTAGAAGGTCTAGCCCAAAAAATTGTAGATGGCACAGT
ACCTCACAAATTGCAAGGTAAGCAAGTGATCCGTCTAGATGTGGTTAGTCTTGTTCAAGGCACAGGTATCCGTGGTCAAT
TCGAAGAACGCATGCAAAAATTAATGGAAGAAATTCGTCAACGCAAAGATGTGATTCTCTTTATTGATGAAATTCATGAA
ATTGTAGGTGCTGGTTCTGCTGGAGATGGCAATATGGATGCTGGCAATATTTTAAAACCAGCCTTGGCCCGTGGTGAGTT
GCAACTCGTTGGTGCTACTACCTTAAATGAATACCGTATTATTGAAAAAGATGCTGCCTTGGAGCGGCGGATGCAGCCGG
TGAAAGTTGACGAACCTTCTGTAGAAGAAACCATTACCATCTTAAAAGGTATCCAACCCAAATATGAAGACTATCATCAT
GTCAAATATAGCCCAGCAGCTATCGAGGCTGCTGCACACTTATCCAATCGCTACATCCAAGACCGATTCCTCCCTGATAA
GGCCATTGACCTTCTGGACGAAGCTGGTTCAAAAATGAATTTAACTCTTAATTTTGTTGACCCTAAAGAGATTGACAAAC
GTCTGATTGAAGCAGAAAACCTCAAAGCTCAAGCAACTCGTGACGAAGATTACGAACGAGCAGCCTATTTCCGTGATCAA
ATTGCGAAATACAAGGAAATGCAAGCTCAAAAAGTCGACGAACAGGATATTCCTATCATTACTGAAAAAACCATTGAAGC
CATCATTGAACAAAAAACCAATATTCCAGTTGGCGACTTGAAAGAAAAAGAACAATCTCAACTCGTTAATTTGGCTAATG
ATTTGAAAGCTCACGTGATTGGCCAAGATGATGCCGTTGACAAAATTGCCAAGGCCATTCGCCGGAACCGTGTGGGATTG
GGAACTCCAAATCGTCCTATTGGTTCTTTCCTATTCGTTGGGCCAACAGGTGTTGGTAAAACAGAGTTGTCTAAGCAACT
AGCTATTGAACTCTTTGGCTCTGCTGACAATATGATTCGCTTTGATATGTCCGAATACATGGAAAAACATGCCGTTGCTA
AATTAGTCGGGGCTCCTCCTGGTTATGTGGGCTATGAAGAAGCTGGCCAGTTAACGGAACAAGTTCGCCGCAACCCATAT
TCACTTATTCTCTTAGATGAGGTGGAAAAGGCTCATCCTGACGTCATGCACATGTTTTTACAAGTTCTTGATGATGGCCG
TTTAACAGATGGTCAAGGACGGACAGTCAGCTTCAAGGATACTATTATTATCATGACCTCTAATGCCGGAACAGGTAAAA
GCGAAGCTTCTGTTGGATTTGGTGCAGCTAGAGAAGGACGAACAAGCTCTGTCCTTGGTGAATTAAGTAACTTCTTCAGC
CCAGAGTTCATGAACCGTTTCGATGGTATTATTGAATTTAAGGCCTTGAGCAAAGATAACCTCTTGCATATCGTTGATTT
AATGCTGGAAGATGTTAATAAGCGCTTAGGCTATAATGGGATTCACCTTGATGTGACACAAAAAGTCAAAGAAAAATTAG
TAGATTTAGGCTATGATCCTAAAATGGGTGCTCGACCACTCCGTCGTACCATCCAAGATTATATCGAAGATGCGATTACG
GACTACTATTTGGAACACCCCACTGAAAAGGACTTGCGTGCCATAATGACAAGTAACAGTAATATCATGATTAAAGCTGC
CAAAAAAGATGAAACGGTAACAGCTAAACAAGATAAGACCGACGAGAACTAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(485-648)

AAA lid domain (AAA_lid_9)

(300-397)

ATPase family associated with various cellular activities (AAA) (AAA)

(162-281)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(656-730)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

85.582

99.083

0.848
  clpE Streptococcus pneumoniae Rx1

83.926

99.476

0.835
  clpE Streptococcus pneumoniae D39

83.926

99.476

0.835
  clpE Streptococcus pneumoniae R6

83.926

99.476

0.835
  clpE Streptococcus pneumoniae TIGR4

83.926

99.476

0.835
  clpC Lactococcus lactis subsp. cremoris KW2

76.63

96.461

0.739
  clpC Bacillus subtilis subsp. subtilis str. 168

51.138

86.37

0.442
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.462

85.19

0.396
  clpC Streptococcus pneumoniae Rx1

48

81.913

0.393
  clpC Streptococcus pneumoniae D39

48

81.913

0.393
  clpC Streptococcus pneumoniae TIGR4

48

81.913

0.393
  clpC Streptococcus mutans UA159

47.573

80.996

0.385
  clpC Streptococcus thermophilus LMD-9

46.635

81.782

0.381
  clpC Streptococcus thermophilus LMG 18311

46.314

81.782

0.379