Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   HG574_RS04110 Genome accession   NZ_CP051541
Coordinates   866905..868689 (+) Length   594 a.a.
NCBI ID   WP_202144434.1    Uniprot ID   -
Organism   Helicobacter pylori strain LIM-001     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 861905..873689
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HG574_RS04080 (HG574_04080) motB 862670..863443 (+) 774 WP_001085351.1 flagellar motor protein MotB -
  HG574_RS04085 (HG574_04085) - 863449..863886 (+) 438 WP_202144431.1 hypothetical protein -
  HG574_RS04090 (HG574_04090) - 863955..865616 (+) 1662 WP_202144432.1 ABC transporter permease/substrate-binding protein -
  HG574_RS04095 (HG574_04095) - 865619..866260 (+) 642 WP_202144433.1 ATP-binding cassette domain-containing protein -
  HG574_RS04100 (HG574_04100) - 866272..866451 (-) 180 WP_000468793.1 hypothetical protein -
  HG574_RS04105 (HG574_04105) - 866443..866904 (+) 462 WP_108368149.1 hypothetical protein -
  HG574_RS04110 (HG574_04110) uvrC 866905..868689 (+) 1785 WP_202144434.1 excinuclease ABC subunit UvrC Machinery gene
  HG574_RS04115 (HG574_04115) - 868700..869965 (+) 1266 WP_202144435.1 homoserine dehydrogenase -
  HG574_RS04120 (HG574_04120) - 869966..870310 (+) 345 WP_139548219.1 YraN family protein -
  HG574_RS04125 (HG574_04125) trxA 870399..870719 (+) 321 WP_000020199.1 thioredoxin -
  HG574_RS04130 (HG574_04130) trxB 870725..871660 (+) 936 WP_000564419.1 thioredoxin-disulfide reductase -
  HG574_RS04135 (HG574_04135) - 871875..872696 (+) 822 WP_202144436.1 glycosyltransferase family 25 protein -
  HG574_RS04140 (HG574_04140) - 872928..873176 (-) 249 WP_000790555.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68549.84 Da        Isoelectric Point: 9.7128

>NTDB_id=439688 HG574_RS04110 WP_202144434.1 866905..868689(+) (uvrC) [Helicobacter pylori strain LIM-001]
MADLLSSLKNLPNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNPRVSLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGASNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLS
ACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSSEDLILEEARSLFNLECVPYRVEIFDT
SHHSNSQCVGGMVVYENHAFQKNSYRRYHLKGSNEYAQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=439688 HG574_RS04110 WP_202144434.1 866905..868689(+) (uvrC) [Helicobacter pylori strain LIM-001]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTCCTAATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCCATCCGTAATAATGAAATCACGCCTA
ATCCTCGCGTAAGCTTACGCATTCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCCTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAGTTGCTCCCTTTAGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTGA
AAATGGAGCGCCTTTCTAGTAACTTGCGTTTTGAAGAAGCCCTAATTTACAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTGGCCAAACTCTATGATTTGGATATTTTCGCTTTTTATGGCGCAAGCAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCGGCGTTTGAAAAAATCCACTCCCTCAATGGGTTTGACA
CCGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTACCTTTGATGCCTGAACAGATCTTGTTGAGC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAGTTTATCTCTCATCAATATTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAGGGCGACAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
GTGAAGATCTGATTTTAGAAGAAGCGCGATCGCTTTTCAATTTAGAGTGCGTGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATTCAAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGCATTCCAAAAAAACTCTTATCGGCG
CTACCATCTAAAAGGCTCTAACGAATACGCTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCTAAAGAGC
CACCGCCTAATTTGTGGGTGATAGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAGGCTTATCGTTCTAAAGGGGGCGCTAAAGACATTAT
CCATACGCCTAGCGATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCACAGATCCACTAAACTTAAAAACATGAAGCAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(205-239)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

97.811

100

0.978