Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   HG575_RS02810 Genome accession   NZ_CP051540
Coordinates   587209..588993 (-) Length   594 a.a.
NCBI ID   WP_202248952.1    Uniprot ID   -
Organism   Helicobacter pylori strain LIM-002     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 582209..593993
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HG575_RS02780 (HG575_02780) - 582800..583048 (+) 249 WP_078245806.1 RNA-binding protein -
  HG575_RS02785 (HG575_02785) - 583249..584070 (-) 822 WP_202248946.1 glycosyltransferase family 25 protein -
  HG575_RS02790 (HG575_02790) trxB 584238..585173 (-) 936 WP_202248948.1 thioredoxin-disulfide reductase -
  HG575_RS02795 (HG575_02795) trxA 585179..585499 (-) 321 WP_000020204.1 thioredoxin -
  HG575_RS02800 (HG575_02800) - 585588..585932 (-) 345 WP_001211672.1 YraN family protein -
  HG575_RS02805 (HG575_02805) - 585933..587198 (-) 1266 WP_202248950.1 homoserine dehydrogenase -
  HG575_RS02810 (HG575_02810) uvrC 587209..588993 (-) 1785 WP_202248952.1 excinuclease ABC subunit UvrC Machinery gene
  HG575_RS02815 (HG575_02815) - 588994..589455 (-) 462 WP_000437183.1 hypothetical protein -
  HG575_RS02820 (HG575_02820) - 589447..589626 (+) 180 WP_000468791.1 hypothetical protein -
  HG575_RS02825 (HG575_02825) - 589638..590279 (-) 642 WP_202248954.1 ATP-binding cassette domain-containing protein -
  HG575_RS02830 (HG575_02830) - 590281..591942 (-) 1662 WP_202248956.1 ABC transporter permease/substrate-binding protein -
  HG575_RS02835 (HG575_02835) - 592011..592448 (-) 438 WP_025444993.1 hypothetical protein -
  HG575_RS02840 (HG575_02840) motB 592454..593227 (-) 774 WP_001085351.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68647.87 Da        Isoelectric Point: 9.7158

>NTDB_id=439665 HG575_RS02810 WP_202248952.1 587209..588993(-) (uvrC) [Helicobacter pylori strain LIM-002]
MADLLSSLKNLPNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIHNNEIVPNPRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEDKITKEEYLKIAKKCLEMIENKDRLIKELELKMERLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGNNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLS
ACSNETLRELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFNLECVPYRVEIFDT
SHHSNSQCVGGMVVYENNAFQKDSYRRYHLKGSNEYAQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLRKRK

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=439665 HG575_RS02810 WP_202248952.1 587209..588993(-) (uvrC) [Helicobacter pylori strain LIM-002]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTCCTAATAGTAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAAGCAAAAAACTTAAAAAAGCGTATCAAAAGCTATTTTTCTATCCATAATAACGAAATCGTGCCCA
ATCCTCGTGCAAGCTTACGCATCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCTAAATACAATATTCTTTTAAGAGATGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGTGGGGCTAAGGATATTTTGGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGGATAAAATCACCAA
AGAAGAATATTTAAAAATCGCTAAAAAATGTTTAGAAATGATTGAAAATAAAGACAGGCTCATCAAAGAGCTTGAATTGA
AAATGGAGCGCCTTTCTAGTAACTTGCGTTTTGAAGAAGCCCTAATTTACAGGGATAGGATTGCAAAAATCCAAAAAATC
GCCCCCTTCACTTGCATGGATTTAGCCAAACTCTACGATTTGGATATTTTTGCTTTTTATAGTGGGAACAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCCCTCAACGGGTTTGACA
CCGATGAGGCGATGAAACAAGCCATTATCAACCATTACCAATCGCATTTGCCTTTGATGCCTGAACAGATTTTATTGAGC
GCTTGTTCTAATGAAACGCTTAGAGAATTGCAAGAATTTATCTCTCATCAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAGGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTCAATTTAGAGTGCGTGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATTCAAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACAATGCATTTCAAAAAGACTCTTATCGGCG
CTACCATTTAAAAGGCTCTAACGAATACGCTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCCAAAGAGC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAGGCTTATCGTTCTAAAGGGGGTGCTAAAGACATTAT
CCATACGCCTAGCGATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAATGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCACAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAAGGTATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAGAAAACGAAAATAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(205-239)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.796

99.832

0.966