Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   HG575_RS00100 Genome accession   NZ_CP051540
Coordinates   14129..16492 (+) Length   787 a.a.
NCBI ID   WP_202248318.1    Uniprot ID   -
Organism   Helicobacter pylori strain LIM-002     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 9129..21492
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HG575_RS00070 (HG575_00070) groES 9152..9508 (-) 357 WP_000671934.1 co-chaperone GroES -
  HG575_RS00075 (HG575_00075) dnaG 9790..11469 (+) 1680 WP_202248312.1 DNA primase -
  HG575_RS00080 (HG575_00080) - 11466..12518 (+) 1053 WP_202248314.1 MnmA/TRMU family protein -
  HG575_RS00085 (HG575_00085) - 12610..13437 (+) 828 WP_202248316.1 DUF5718 family protein -
  HG575_RS00090 (HG575_00090) comB2 13583..13864 (+) 282 WP_001272686.1 TrbC/VirB2 family protein Machinery gene
  HG575_RS00095 (HG575_00095) comB3 13864..14127 (+) 264 WP_187892425.1 competence protein ComB Machinery gene
  HG575_RS00100 (HG575_00100) comB4 14129..16492 (+) 2364 WP_202248318.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  HG575_RS00110 (HG575_00110) - 16794..18134 (+) 1341 WP_039087052.1 COG3014 family protein -
  HG575_RS00115 (HG575_00115) cheV1 18233..19198 (+) 966 WP_202248320.1 chemotaxis protein CheV1 -
  HG575_RS00120 (HG575_00120) nspC 19195..20412 (+) 1218 WP_202248322.1 carboxynorspermidine decarboxylase -
  HG575_RS00125 (HG575_00125) lpxE 20422..20955 (-) 534 WP_237419606.1 lipid A 1-phosphatase LpxE -

Sequence

Protein


Download         Length: 787 a.a.        Molecular weight: 90097.61 Da        Isoelectric Point: 8.5251

>NTDB_id=439653 HG575_RS00100 WP_202248318.1 14129..16492(+) (comB4) [Helicobacter pylori strain LIM-002]
MLEKLLGAIKQKVSNYFLGALPKSYSMSEENNILGLYDEHFLLTKNENLVGILRLEGVSYTHLSTEQLQDLFTERQMALD
SLEKVVARLVVKRRKIDHQQNIQADSQYLQAILNQFENKEVYENQYFLVLESTHSLQGVLEHKKKSLMHANRENFKDILS
YKAHFLQETLKSLEIQLKNYAPKLLSSKEVLNFYAEYINGFDLPLKPLVGGYLSDSYIASSITFEKDYFIQEGFNQKTYN
RLIGIKAYESERITSIAIGALLYQETPLDIIFSIEPMSAHKTLSFLKERAKFSMSNLIKNELLEYQELVKTKRLSMQKFA
LNILIKAPSLEDLDAQTSLILGLLFKENLVGVIETFGLKGGYFSFFPERIHLNHRLRFLTSKALACLMVFERQNLGFKAN
SWGNSPLSVFKNLDYSPFLFNFHNQEVSHKNAKEIARVNGHTLVIGATGSGKSTLISFLMMSALKYQNMRLLAFDRMQGL
YSFTKFFKGHYHDGQSFSINPFCLEPNLQNLEFLQSFFLSMLDLAPSRDKEALEDMNAVSSAIKSLYETLYPKDFSLLDF
KETLKRTSSNQLSLSLEPYLNNPLFNALNDALNSNAFLNVINLDAITQNPKDLGLLAYYLFYKILEESRKNDSGFLVFLD
EFKSYVENDLLNTKINALITQARKANGVVVLALQDIYQLSGVKNAHSFLSNMGTLILYPQKNARELKHHFNVPLSETEIS
FLENTPLYARQVLVKNLGNGSSNMIDVSLEGLGRYLKIFNSDSSHVNKVKALQKDYPTEWREKLLKS

Nucleotide


Download         Length: 2364 bp        

>NTDB_id=439653 HG575_RS00100 WP_202248318.1 14129..16492(+) (comB4) [Helicobacter pylori strain LIM-002]
ATGCTAGAAAAGCTTTTAGGCGCTATCAAGCAAAAAGTTTCAAATTATTTTTTAGGGGCTTTGCCTAAAAGCTATTCAAT
GAGCGAAGAAAACAACATTTTAGGCTTGTATGATGAGCATTTTTTGCTCACTAAAAACGAAAACTTAGTGGGTATCCTCC
GTTTAGAGGGGGTGAGTTACACCCATTTAAGCACAGAGCAATTGCAAGATCTTTTCACCGAGCGCCAAATGGCGTTGGAT
TCTTTAGAAAAAGTCGTGGCACGCCTGGTGGTTAAAAGGCGTAAAATTGATCACCAACAAAACATTCAAGCTGACTCTCA
ATACTTGCAAGCGATCTTGAATCAGTTTGAAAACAAAGAAGTGTATGAGAATCAGTATTTTTTAGTTTTAGAAAGCACTC
ACTCTTTACAAGGTGTTTTGGAGCATAAGAAAAAATCTCTCATGCATGCCAATAGGGAAAATTTTAAGGATATTCTCTCT
TATAAAGCGCATTTTTTGCAAGAAACTTTAAAAAGCCTAGAAATCCAGCTCAAAAATTATGCCCCCAAACTCTTAAGCTC
TAAAGAGGTTTTGAATTTTTATGCAGAATACATTAATGGGTTTGATCTCCCCTTAAAGCCTTTAGTAGGGGGGTATTTGA
GCGATAGTTATATCGCTAGCTCTATCACTTTTGAAAAAGATTATTTCATTCAAGAGGGTTTTAACCAAAAAACCTATAAC
CGCTTGATTGGCATTAAAGCTTATGAGAGCGAACGCATCACTTCTATAGCGATCGGAGCGCTTTTATACCAAGAGACTCC
ACTAGATATTATCTTTTCTATAGAGCCTATGAGTGCGCATAAAACGCTGAGTTTTTTAAAAGAGAGAGCCAAGTTTAGCA
TGTCTAATCTTATTAAAAACGAGCTGCTAGAATACCAAGAATTAGTCAAAACCAAACGATTATCCATGCAAAAATTCGCC
CTAAATATTCTTATCAAAGCCCCCAGTTTAGAGGATTTAGACGCTCAAACGAGCTTAATTTTAGGGCTTTTATTTAAAGA
AAACTTAGTGGGCGTTATAGAAACTTTTGGCTTGAAAGGGGGGTATTTTTCCTTTTTCCCTGAACGCATCCATTTAAACC
ACCGCTTGCGTTTTTTGACCTCTAAAGCCCTAGCGTGTTTAATGGTGTTTGAAAGGCAAAATTTAGGCTTTAAGGCTAAT
TCATGGGGGAATAGCCCTTTGAGCGTGTTTAAAAATTTGGATTATTCCCCTTTTTTATTCAATTTCCACAACCAAGAAGT
GAGCCACAAGAACGCTAAAGAAATCGCCAGAGTGAATGGGCATACTTTAGTTATAGGGGCTACCGGAAGCGGTAAAAGCA
CGCTGATTAGCTTTTTAATGATGAGCGCTTTGAAATACCAAAACATGCGCCTTTTAGCCTTTGATAGGATGCAGGGGCTG
TATTCTTTCACCAAATTTTTTAAAGGGCATTACCATGACGGCCAATCTTTTAGCATCAACCCCTTTTGTTTAGAGCCTAA
TTTGCAGAATTTGGAATTTTTGCAATCCTTCTTTTTGAGCATGCTTGATCTTGCCCCTTCAAGGGATAAAGAAGCCTTGG
AAGATATGAATGCGGTTTCTAGTGCGATTAAGAGCCTTTATGAGACTTTATACCCTAAAGATTTTAGTTTGCTAGACTTT
AAAGAAACGCTTAAAAGAACCTCATCTAACCAATTAAGTTTGAGCTTGGAGCCGTATTTGAATAACCCCCTTTTTAACGC
TTTGAATGACGCACTCAATTCCAACGCTTTTTTAAATGTAATCAACTTAGACGCTATCACCCAAAACCCTAAAGACTTAG
GGCTTTTAGCCTATTACTTGTTTTATAAAATTTTAGAAGAATCCAGGAAAAACGACAGCGGTTTTTTGGTTTTTTTAGAC
GAGTTTAAATCCTATGTGGAAAACGATTTATTGAACACTAAAATTAACGCTTTAATCACGCAAGCCAGGAAAGCTAATGG
CGTGGTGGTGTTGGCTTTGCAAGATATTTACCAACTCAGCGGGGTCAAAAACGCCCATAGTTTTTTAAGCAACATGGGGA
CTCTTATTTTGTATCCGCAAAAAAACGCTAGGGAGTTGAAACACCACTTCAATGTGCCTTTGAGCGAAACTGAAATTTCA
TTTTTAGAAAACACGCCTTTGTATGCCAGGCAGGTTTTAGTCAAAAATCTGGGTAATGGGAGCTCCAACATGATTGATGT
GAGTTTGGAGGGCTTGGGGCGTTATTTGAAAATCTTTAATTCGGATTCTAGTCATGTCAATAAAGTGAAAGCGTTACAAA
AAGACTACCCTACAGAGTGGCGTGAGAAACTTTTGAAGAGCTAG

Domains

Predicted by InterproScan.

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(176-375)

FtsK/SpoIIIE family (FtsK_SpoIIIE)

(426-466)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

97.459

100

0.975