Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   HG578_RS03800 Genome accession   NZ_CP051537
Coordinates   808281..810065 (+) Length   594 a.a.
NCBI ID   WP_202135159.1    Uniprot ID   -
Organism   Helicobacter pylori strain LIM-005     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 803281..815065
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HG578_RS03770 (HG578_03765) motB 804047..804820 (+) 774 WP_001085324.1 flagellar motor protein MotB -
  HG578_RS03775 (HG578_03770) - 804826..805263 (+) 438 WP_001039460.1 hypothetical protein -
  HG578_RS03780 (HG578_03775) - 805332..806993 (+) 1662 WP_202135157.1 ABC transporter permease/substrate-binding protein -
  HG578_RS03785 (HG578_03780) - 806995..807636 (+) 642 WP_202135158.1 ATP-binding cassette domain-containing protein -
  HG578_RS03790 (HG578_03785) - 807648..807827 (-) 180 WP_001926337.1 hypothetical protein -
  HG578_RS03795 (HG578_03790) - 807819..808280 (+) 462 WP_000437184.1 hypothetical protein -
  HG578_RS03800 (HG578_03795) uvrC 808281..810065 (+) 1785 WP_202135159.1 excinuclease ABC subunit UvrC Machinery gene
  HG578_RS03805 (HG578_03800) - 810076..811341 (+) 1266 WP_202134431.1 homoserine dehydrogenase -
  HG578_RS03810 (HG578_03805) - 811342..811686 (+) 345 WP_108337794.1 YraN family protein -
  HG578_RS03815 (HG578_03810) trxA 811778..812098 (+) 321 WP_000020199.1 thioredoxin -
  HG578_RS03820 (HG578_03815) trxB 812104..813039 (+) 936 WP_000564419.1 thioredoxin-disulfide reductase -
  HG578_RS03825 (HG578_03820) - 813422..814243 (+) 822 WP_202134432.1 glycosyltransferase family 25 protein -
  HG578_RS03830 (HG578_03825) - 814462..814710 (-) 249 WP_000790555.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68722.01 Da        Isoelectric Point: 9.7529

>NTDB_id=439626 HG578_RS03800 WP_202135159.1 808281..810065(+) (uvrC) [Helicobacter pylori strain LIM-005]
MADLLSSLKNLPNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNPRTSLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPSVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEDKITKEEYLKIAKKCLEMIENKDRLIKELELKMERLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGASNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLIPEQILLN
ACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEVRSLFNLECVPYRVEIFDT
SHHSNSQCVGGMVVYENNAFQKNSYRRYHLKGSNEYDQMSELLTRRALDFAKEPPPNLWVIDGGRVQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSNTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=439626 HG578_RS03800 WP_202135159.1 808281..810065(+) (uvrC) [Helicobacter pylori strain LIM-005]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTCCTAATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAACT
GCTCTATATCGGTAAGGCAAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTATCCGTAATAATGAAATCACGCCCA
ATCCTCGCACCAGCTTACGCATCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTAGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTGGACAGCTTGTATGAATTGCTCCCGTTGGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGGATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAAAATGTTTAGAAATGATTGAAAATAAAGACAGGCTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAGCAATTTGCGTTTTGAAGAAGCCCTAATTTACAGGGATAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTGGCCAAACTCTACGATTTGGATATTTTTGCTTTTTATGGCGCAAGCAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCCCTTAATGGGTTTGACA
CCGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATACCAGAACAGATTTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCTCATCAATATTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAGGGTGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGTGCGATCGCTCTTTAATTTAGAGTGCGTGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATTCAAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACAATGCATTTCAAAAAAACTCTTATCGGCG
CTACCATCTAAAAGGCTCTAACGAATACGATCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCCAAAGAGC
CACCGCCTAATTTGTGGGTGATAGATGGAGGGAGGGTGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAGGCTTATCGTTCTAAAGGGGGCGCTAAAGACATTAT
CCATACGCCCAGCAATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCACAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATTTAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

97.306

100

0.973