Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   HG581_RS03955 Genome accession   NZ_CP051535
Coordinates   847842..849626 (+) Length   594 a.a.
NCBI ID   WP_202137606.1    Uniprot ID   -
Organism   Helicobacter pylori strain LIM-008     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 842842..854626
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HG581_RS03925 (HG581_03925) motB 843606..844379 (+) 774 WP_202137602.1 flagellar motor protein MotB -
  HG581_RS03930 (HG581_03930) - 844385..844822 (+) 438 WP_164855421.1 hypothetical protein -
  HG581_RS03935 (HG581_03935) - 844891..846552 (+) 1662 WP_202137603.1 glycine betaine ABC transporter substrate-binding protein -
  HG581_RS03940 (HG581_03940) - 846556..847206 (+) 651 WP_202137604.1 ATP-binding cassette domain-containing protein -
  HG581_RS03945 (HG581_03945) - 847209..847388 (-) 180 WP_000468793.1 hypothetical protein -
  HG581_RS03950 (HG581_03950) - 847380..847841 (+) 462 WP_202137605.1 hypothetical protein -
  HG581_RS03955 (HG581_03955) uvrC 847842..849626 (+) 1785 WP_202137606.1 excinuclease ABC subunit UvrC Machinery gene
  HG581_RS03960 (HG581_03960) - 849637..850902 (+) 1266 WP_202137607.1 homoserine dehydrogenase -
  HG581_RS03965 (HG581_03965) - 850903..851247 (+) 345 WP_202137608.1 YraN family protein -
  HG581_RS03970 (HG581_03970) trxA 851336..851656 (+) 321 WP_000020200.1 thioredoxin -
  HG581_RS03975 (HG581_03975) trxB 851662..852597 (+) 936 WP_202137609.1 thioredoxin-disulfide reductase -
  HG581_RS03980 (HG581_03980) - 852765..853586 (+) 822 WP_202137610.1 glycosyltransferase family 25 protein -
  HG581_RS03985 (HG581_03985) - 853824..854072 (-) 249 WP_000790557.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68660.78 Da        Isoelectric Point: 9.5806

>NTDB_id=439586 HG581_RS03955 WP_202137606.1 847842..849626(+) (uvrC) [Helicobacter pylori strain LIM-008]
MADLLSSLKNLSNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIHNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEDKITKEEYLKIAKECLEMIENKDRLIKEIELKMERLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGASNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLS
DCSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDRILEEARSLFNLECVPYRVEIFDT
SHHANSQCVGGMVVYENHAFQKDSYRRYHLKGSNEYAQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=439586 HG581_RS03955 WP_202137606.1 847842..849626(+) (uvrC) [Helicobacter pylori strain LIM-008]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTAACAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAAGCAAAAAACTTAAAAAAGCGCATCAAAAGCTATTTTTCTATCCATAATAATGAAATCACGCCCA
ATCATCGTGCAAGCTTACGAATCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCTAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTGGACAGCTTGTATGAGTTGCTCCCATTAGTTCAAAAGAAA
AATTGCATTAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGGATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAGGCTCATCAAAGAGATTGAATTGA
AAATGGAGCGCCTTTCTAGTAACTTGCGTTTTGAAGAAGCCCTCATTTACAGGGACAGGATAGCTAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTGGCCAAACTCTACGATTTGGATATTTTTGCTTTTTATGGCGCAAGCAATAAGGCGGT
CTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCCCTTAATGGGTTTGACA
CTGATGAGGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCTGAACAGATCTTATTGAGC
GATTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCTCATCAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAGGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCGGATTTTAGAAGAAGCGCGATCGCTCTTCAATTTAGAGTGCGTGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATGCTAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGCATTTCAAAAAGACTCTTATCGGCG
CTACCATCTAAAAGGCTCTAACGAATACGCTCAAATGAGCGAATTGCTCACCAGAAGAGCCTTAGACTTTGCCAAAGAGC
CACCGCCTAATTTGTGGGTGATAGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATCTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAGGCTTATCGTTCTAAAGGGGGTGCTAAAGACATTAT
CCATACGCCTAGCGATACTTTTAAATTACTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCACAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATTTAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

97.138

100

0.971