Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   HG581_RS00100 Genome accession   NZ_CP051535
Coordinates   14157..16520 (+) Length   787 a.a.
NCBI ID   WP_202138041.1    Uniprot ID   -
Organism   Helicobacter pylori strain LIM-008     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 9157..21520
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HG581_RS00070 (HG581_00070) groES 9174..9530 (-) 357 WP_000671958.1 co-chaperone GroES -
  HG581_RS00075 (HG581_00075) dnaG 9819..11498 (+) 1680 WP_202138038.1 DNA primase -
  HG581_RS00080 (HG581_00080) - 11495..12547 (+) 1053 WP_202138039.1 MnmA/TRMU family protein -
  HG581_RS00085 (HG581_00085) - 12637..13464 (+) 828 WP_202138040.1 DUF5718 family protein -
  HG581_RS00090 (HG581_00090) comB2 13611..13892 (+) 282 WP_001272690.1 TrbC/VirB2 family protein Machinery gene
  HG581_RS00095 (HG581_00095) comB3 13892..14155 (+) 264 WP_000584951.1 hypothetical protein Machinery gene
  HG581_RS00100 (HG581_00100) comB4 14157..16520 (+) 2364 WP_202138041.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  HG581_RS00110 (HG581_00110) - 16825..18165 (+) 1341 WP_202138488.1 COG3014 family protein -
  HG581_RS00115 (HG581_00115) cheV1 18265..19230 (+) 966 WP_000785448.1 chemotaxis protein CheV1 -
  HG581_RS00120 (HG581_00120) nspC 19227..20444 (+) 1218 WP_202138042.1 carboxynorspermidine decarboxylase -
  HG581_RS00125 (HG581_00125) lpxE 20579..21115 (-) 537 WP_237389076.1 lipid A 1-phosphatase LpxE -

Sequence

Protein


Download         Length: 787 a.a.        Molecular weight: 90156.64 Da        Isoelectric Point: 8.7199

>NTDB_id=439571 HG581_RS00100 WP_202138041.1 14157..16520(+) (comB4) [Helicobacter pylori strain LIM-008]
MLEKLLSAVKQKVSNYFLGVLPKSYSMSEENNILGLYDEHFLLTKNENLVGILRLEGVSYTHLSTEQLQDLFTERQMALD
SLEKVVARLVVKRRKIDHQQNIQTDSQYLQAILNQFENKEVYENQYFLVLESTHSLQGVLEHKKKSLMHANKENFKDILS
YKAHFLQETLKSLEIQLKNYAPKLLSSKEVLNFYAEYINGFDLPLKPLVGGYLSDSYIASSITFEKDYFIQESFNQKTYN
RLIGIKAYESERITSIAIGALLYQETPLDIIFSIEPMSAHKTLSFLKERAKFSMSNLVKNELLEYQELVKTKRLSMQKFA
LNILIKASSLEDLDAQTSLVLGLLFKENLVGVIETFGLKGGYFSFFPERIHLNHRLRFLTSKALACLMVFERQNLGFKAN
SWGNSPLSVFKNLDYSPFLFNFHNQEVSHNNAKEVARVNGHTLIIGATGSGKSTLISFLMMSALKYQNMRLLAFDRMQGL
YSFTKFFKGHYHDGKSFSINPFCLEPNLQNLEFLQSFFLSMFDLAPSRDKEALEDMNAISGAIKSLYETLYPKAFSLLDF
KETLKRTSSNQLGLSLEPYLNNPLFNALNDAFNSNAFLNVINLDTITQNPKDLGLLAYYLFYKILEESRKNDSGFLVFLD
EFKSYVENDLLNAKINALITQARKANGVVVLALQDIYQLSGVKNAHSFLSNMGTLILYPQKNARELKHHFNVPLSETEIS
FLENTPLYARQVLVKNLGNGNSNMIDVSLESLGRYLKIFNSDSSHVNKVKALQKDYPTEWREKLLKS

Nucleotide


Download         Length: 2364 bp        

>NTDB_id=439571 HG581_RS00100 WP_202138041.1 14157..16520(+) (comB4) [Helicobacter pylori strain LIM-008]
ATGTTAGAAAAGCTTTTGAGCGCCGTCAAACAAAAAGTTTCAAACTATTTTTTAGGGGTTTTACCTAAAAGCTATTCTAT
GAGCGAAGAAAACAACATTTTAGGCTTGTATGATGAGCACTTTTTACTCACTAAAAACGAAAACTTAGTGGGCATCCTCC
GTTTAGAGGGGGTGAGTTACACCCATTTAAGCACAGAGCAATTGCAAGATCTTTTCACCGAGCGCCAAATGGCGTTGGAT
TCTTTAGAAAAGGTCGTGGCGCGCCTAGTGGTTAAAAGGCGTAAAATTGATCACCAACAAAACATTCAAACTGACTCTCA
ATACTTGCAAGCGATTTTGAATCAATTTGAAAATAAAGAAGTGTATGAAAATCAGTATTTTTTAGTTTTAGAAAGCACTC
ACTCTCTACAAGGTGTTTTGGAGCATAAGAAAAAATCTCTCATGCATGCCAATAAGGAAAATTTTAAGGATATTCTCTCT
TATAAAGCGCATTTTTTGCAAGAAACTTTAAAAAGCCTAGAAATCCAGCTCAAAAATTATGCCCCCAAACTCTTAAGCTC
TAAAGAGGTTTTGAATTTTTATGCAGAATATATTAATGGGTTTGATCTCCCTTTAAAACCCCTAGTAGGGGGGTATTTGA
GCGATAGCTATATCGCTAGTTCTATCACTTTTGAAAAAGATTATTTCATTCAAGAAAGCTTTAATCAAAAAACCTATAAC
CGCTTGATTGGCATTAAAGCTTATGAAAGCGAACGCATCACTTCTATAGCGATTGGAGCGCTTTTATACCAAGAAACGCC
TTTAGATATTATCTTTTCTATAGAGCCTATGAGTGCGCATAAAACGCTGAGTTTTTTAAAAGAGAGAGCCAAGTTTAGCA
TGTCCAATCTCGTTAAAAACGAGCTGCTAGAATACCAAGAATTAGTCAAAACCAAACGCCTATCCATGCAAAAATTCGCC
CTAAACATTCTTATCAAAGCCTCCAGTTTAGAGGATTTAGACGCTCAAACAAGCTTAGTTTTAGGGCTTTTATTTAAAGA
AAACTTAGTGGGCGTTATAGAAACTTTTGGCTTGAAAGGGGGGTATTTTTCCTTTTTCCCTGAACGCATCCATTTAAACC
ACCGCTTGCGTTTTTTAACCTCTAAAGCCCTAGCGTGTTTAATGGTGTTTGAAAGGCAAAATTTAGGCTTTAAGGCTAAT
TCATGGGGGAATAGCCCTTTGAGCGTGTTTAAAAATTTGGATTATTCCCCTTTTTTATTCAATTTCCACAACCAAGAAGT
GAGCCACAACAACGCTAAAGAAGTCGCTAGAGTGAATGGGCATACTCTAATCATAGGGGCTACCGGGAGCGGTAAAAGCA
CGCTGATTAGCTTTTTAATGATGAGCGCTTTGAAATACCAAAACATGCGCCTTTTGGCTTTTGACAGGATGCAAGGGCTG
TATTCTTTCACAAAATTTTTTAAAGGGCATTACCATGACGGCAAATCTTTTAGCATCAACCCCTTTTGCTTAGAGCCTAA
TTTGCAGAATTTAGAATTTTTGCAATCCTTCTTTTTGAGCATGTTTGATCTTGCCCCTTCAAGGGATAAAGAAGCCTTAG
AAGACATGAATGCGATTTCTGGCGCGATTAAGAGTCTTTATGAGACTTTATACCCTAAAGCTTTTAGTTTGCTAGATTTT
AAAGAAACGCTTAAAAGAACCTCATCTAACCAATTGGGCTTGAGTTTAGAGCCGTATTTGAATAACCCCCTTTTTAACGC
TTTGAATGACGCGTTCAACTCCAACGCTTTTTTAAATGTGATAAACCTAGACACTATCACCCAAAACCCTAAAGACTTAG
GGCTTTTAGCCTATTATTTGTTTTATAAAATCTTAGAAGAATCCAGGAAAAACGACAGCGGTTTTTTGGTTTTTTTAGAC
GAGTTTAAATCCTATGTGGAGAACGATTTATTGAACGCTAAAATTAACGCTTTAATCACGCAAGCCAGAAAGGCTAATGG
CGTGGTGGTGTTGGCTTTGCAAGACATTTACCAATTAAGCGGGGTTAAAAACGCCCATAGTTTTTTAAGCAACATGGGGA
CTCTTATCTTGTATCCGCAAAAAAACGCTAGGGAGTTGAAACACCATTTCAATGTGCCTTTAAGCGAAACTGAAATTTCT
TTTTTAGAAAACACCCCTTTGTATGCCAGGCAGGTTTTAGTCAAAAATTTGGGTAACGGGAATTCTAACATGATTGATGT
GAGTTTGGAAAGTTTAGGGCGTTATTTGAAAATCTTTAATTCGGATTCTAGCCATGTGAACAAAGTGAAAGCGTTACAAA
AAGACTACCCTACAGAGTGGCGTGAGAAACTTTTGAAGAGCTAG

Domains

Predicted by InterproScan.

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(176-375)

FtsK/SpoIIIE family (FtsK_SpoIIIE)

(426-466)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

97.967

100

0.98