Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   HG582_RS04040 Genome accession   NZ_CP051534
Coordinates   858486..860270 (+) Length   594 a.a.
NCBI ID   WP_202143504.1    Uniprot ID   -
Organism   Helicobacter pylori strain LIM-009     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 853486..865270
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HG582_RS04005 (HG582_04005) - 853600..853842 (+) 243 Protein_796 osmoprotection protein -
  HG582_RS04010 (HG582_04010) - 853856..854428 (-) 573 WP_000916527.1 Hpy99I family type II restriction endonuclease -
  HG582_RS04015 (HG582_04015) - 854422..855240 (-) 819 WP_000125522.1 site-specific DNA-methyltransferase -
  HG582_RS04020 (HG582_04020) - 855629..857197 (+) 1569 WP_237392737.1 ABC transporter permease/substrate-binding protein -
  HG582_RS04025 (HG582_04025) - 857201..857842 (+) 642 WP_202143503.1 ATP-binding cassette domain-containing protein -
  HG582_RS04030 (HG582_04030) - 857853..858032 (-) 180 WP_000468798.1 hypothetical protein -
  HG582_RS04035 (HG582_04035) - 858024..858485 (+) 462 WP_115019102.1 hypothetical protein -
  HG582_RS04040 (HG582_04040) uvrC 858486..860270 (+) 1785 WP_202143504.1 excinuclease ABC subunit UvrC Machinery gene
  HG582_RS04045 (HG582_04045) - 860281..861546 (+) 1266 WP_202143505.1 homoserine dehydrogenase -
  HG582_RS04050 (HG582_04050) - 861547..861891 (+) 345 WP_001969146.1 YraN family protein -
  HG582_RS04055 (HG582_04055) trxA 861983..862303 (+) 321 WP_000020199.1 thioredoxin -
  HG582_RS04060 (HG582_04060) trxB 862309..863244 (+) 936 WP_202143506.1 thioredoxin-disulfide reductase -
  HG582_RS04065 (HG582_04065) - 863602..864423 (+) 822 WP_202143507.1 glycosyltransferase family 25 protein -
  HG582_RS04070 (HG582_04070) - 864640..864888 (-) 249 WP_000790557.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68496.77 Da        Isoelectric Point: 9.7912

>NTDB_id=439563 HG582_RS04040 WP_202143504.1 858486..860270(+) (uvrC) [Helicobacter pylori strain LIM-009]
MADLLSSLKNLPNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIHNNEITPNPRVSLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEGKITKEEYLKIAKKCLEMIENKDRLIKELELKMERLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGGNNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLIPEQILLN
ACSNEALKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSSEDRILEEARSLFNLECVPYRVEIFDT
SHHANSQCVGGMVVYENNAFQKNSYRRYHLKGSNEYAQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=439563 HG582_RS04040 WP_202143504.1 858486..860270(+) (uvrC) [Helicobacter pylori strain LIM-009]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTCCTAATAGTAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAACTTAAAAAAGCGCATCAAAAGCTATTTTTCCATCCATAATAATGAAATCACTCCTA
ATCCTCGCGTAAGCTTACGCATCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTGGAAAATTCTTTGATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGTGGGGCTAAGGATATTTTGGATAGCTTGTATGAATTGCTCCCTTTGGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGGGTAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAAAATGTTTAGAAATGATTGAAAATAAAGACAGGCTCATCAAAGAGCTTGAATTGA
AAATGGAGCGCCTTTCTAGTAACTTGCGTTTTGAAGAAGCCCTAATTTACAGGGATAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTACGATTTGGATATTTTTGCTTTTTATGGCGGGAACAATAAGGCGGT
GTTAGTGAAAATGTTCATGCGCGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCCCTTAATGGGTTTGACA
CCGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATACCAGAACAGATTTTATTGAAC
GCTTGCTCTAACGAAGCGCTTAAAGAATTGCAAGAATTTATCTCTCATCAATATTCTAAAAAAATCGCTCTTAGTATTCC
TAAAAAAGGCGACAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
GTGAAGATCGGATTTTAGAAGAAGCGCGATCGCTTTTCAATTTAGAGTGCGTGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGAGGAATGGTCGTGTATGAAAATAACGCCTTCCAAAAAAACTCTTATCGGCG
CTACCATTTAAAAGGCTCTAACGAATACGCTCAAATGAGCGAGTTGCTCACCAGAAGAGCCTTAGACTTTGCCAAAGAGC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGAGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATCAT
CCATACGCCTAGCGATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTGTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(205-239)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.801

100

0.968