Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   HG583_RS04480 Genome accession   NZ_CP051533
Coordinates   954667..956451 (+) Length   594 a.a.
NCBI ID   WP_202142564.1    Uniprot ID   -
Organism   Helicobacter pylori strain LIM-010     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 949667..961451
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HG583_RS04450 (HG583_04440) motB 950431..951204 (+) 774 WP_202142560.1 flagellar motor protein MotB -
  HG583_RS04455 (HG583_04445) - 951210..951647 (+) 438 WP_000802458.1 hypothetical protein -
  HG583_RS04460 (HG583_04450) - 951716..953377 (+) 1662 WP_202142561.1 ABC transporter permease/substrate-binding protein -
  HG583_RS04465 (HG583_04455) - 953381..954022 (+) 642 WP_202142562.1 ATP-binding cassette domain-containing protein -
  HG583_RS04470 (HG583_04460) - 954034..954213 (-) 180 WP_000468793.1 hypothetical protein -
  HG583_RS04475 (HG583_04465) - 954205..954666 (+) 462 WP_202142563.1 hypothetical protein -
  HG583_RS04480 (HG583_04470) uvrC 954667..956451 (+) 1785 WP_202142564.1 excinuclease ABC subunit UvrC Machinery gene
  HG583_RS04485 (HG583_04475) - 956462..957727 (+) 1266 WP_202142565.1 homoserine dehydrogenase -
  HG583_RS04490 (HG583_04480) - 957728..958072 (+) 345 WP_001211674.1 YraN family protein -
  HG583_RS04495 (HG583_04485) trxA 958161..958481 (+) 321 WP_000020199.1 thioredoxin -
  HG583_RS04500 (HG583_04490) trxB 958487..959422 (+) 936 WP_202142566.1 thioredoxin-disulfide reductase -
  HG583_RS04505 (HG583_04495) - 959806..960627 (+) 822 WP_187888219.1 glycosyltransferase family 25 protein -
  HG583_RS04510 (HG583_04500) - 960842..961090 (-) 249 WP_000790557.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68858.06 Da        Isoelectric Point: 9.7529

>NTDB_id=439541 HG583_RS04480 WP_202142564.1 954667..956451(+) (uvrC) [Helicobacter pylori strain LIM-010]
MADLLSSLKNLPNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNHRVSLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPSVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEDKITKEEYLKIAKECLEMIENKDRLIKELELKMERLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGASNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQEFISHQYSKKIALNIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDRILEEARSLFNLECVPYRVEIFDT
SHHSNSQCVGGMVVYENHAFQKNSYRRYHLKGSNEYDQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPNNTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRK

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=439541 HG583_RS04480 WP_202142564.1 954667..956451(+) (uvrC) [Helicobacter pylori strain LIM-010]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTCCTAATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAACT
GCTCTATATCGGTAAGGCAAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTATCCGTAATAATGAAATCACGCCCA
ATCATCGCGTAAGCTTACGCATCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTAGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTGGACAGCTTGTATGAATTGCTCCCGTTGGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGGATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAGGCTCATCAAAGAGCTTGAATTGA
AAATGGAGCGTCTTTCTAGTAACTTGCGTTTTGAAGAAGCCCTAATTTACAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCCTTCACTTGCATGGATTTAGCCAAACTCTACGATTTGGATATTTTTGCTTTTTATGGCGCAAGCAATAAGGCGGT
CTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCCCTTAATGGGTTTGACA
CCGATGAAGCGATGAAACAAGCCATTATCAACCATTACCAATCGCATTTGCCTTTGATGCCTGAACAAATTCTATTAAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAGTTTATCTCTCATCAATATTCTAAAAAAATCGCTCTTAATATCCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCGGATTTTAGAAGAAGCGCGATCGCTTTTCAATTTAGAGTGCGTGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATTCAAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGCATTCCAAAAAAACTCTTACCGGCG
CTACCATTTAAAAGGCTCTAACGAATACGATCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCTAAAGAGC
CACCGCCTAATTTGTGGGTAATAGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGTTCTAAAGGGGGCGCTAAAGACATTAT
CCATACGCCTAACAATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAAAATAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrB/uvrC motif (UVR)

(205-239)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

97.47

99.832

0.973