Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   HG583_RS00100 Genome accession   NZ_CP051533
Coordinates   14264..16627 (+) Length   787 a.a.
NCBI ID   WP_202142978.1    Uniprot ID   -
Organism   Helicobacter pylori strain LIM-010     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 9264..21627
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HG583_RS00070 (HG583_00070) groES 9285..9641 (-) 357 WP_033767138.1 co-chaperone GroES -
  HG583_RS00075 (HG583_00075) dnaG 9923..11602 (+) 1680 WP_202142975.1 DNA primase -
  HG583_RS00080 (HG583_00080) - 11599..12651 (+) 1053 WP_202142976.1 MnmA/TRMU family protein -
  HG583_RS00085 (HG583_00085) - 12744..13571 (+) 828 WP_202142977.1 DUF5718 family protein -
  HG583_RS00090 (HG583_00090) comB2 13718..13999 (+) 282 WP_001272690.1 TrbC/VirB2 family protein Machinery gene
  HG583_RS00095 (HG583_00095) comB3 13999..14262 (+) 264 WP_000584973.1 hypothetical protein Machinery gene
  HG583_RS00100 (HG583_00100) comB4 14264..16627 (+) 2364 WP_202142978.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  HG583_RS00110 (HG583_00110) - 16839..18269 (+) 1431 WP_202142979.1 COG3014 family protein -
  HG583_RS00115 (HG583_00115) cheV1 18370..19335 (+) 966 WP_000785446.1 chemotaxis protein CheV1 -
  HG583_RS00120 (HG583_00120) nspC 19332..20549 (+) 1218 WP_202142980.1 carboxynorspermidine decarboxylase -
  HG583_RS00125 (HG583_00125) lpxE 20546..21091 (-) 546 WP_237389125.1 lipid A 1-phosphatase LpxE -

Sequence

Protein


Download         Length: 787 a.a.        Molecular weight: 90170.73 Da        Isoelectric Point: 8.6160

>NTDB_id=439528 HG583_RS00100 WP_202142978.1 14264..16627(+) (comB4) [Helicobacter pylori strain LIM-010]
MLEKLLGAIKQKVSNYFLGVLPKSYSMGEENNILGLYDEHFLLTKNENLVGILRLEGVSYTHLSTEQLQDLFTERQMALD
SLEKVVARLVVKRRKIDYKQSIQSDSQYLQAILNQFENKEVHENQYFLVLESAHSLQGVLEHKKKSFMHANRENFKDILS
YKVHFLQETLKSLEIQLKNYAPKLLSSKEVLNFYAEYINGFDLPLKPLVGGYLSDSYIASSITFEKDYFIQESFNQKTYN
RLIGIKAYESERITSIAVGALLYQETPLDIIFSIEPMSTHKTLSFLKERAKFSMSNLVKNELLEYQELVKTKRLSMQKFA
LNVLIKAPSLEDLDTQTSLILGLLFKENLVGVIETFGLKGGYFSFFPERIHLNHRLRFLTSKALACLMVFERQNLGFKAN
SWGNSPLSVFKNLDYSPFLFNFHNQEVSHNNAKEIARVNGHTLVIGATGSGKSTLISFLMMSALKYQNMRLLAFDRMHGL
YSFTKFFKGHYHDGQSFSINPFCLEPNLQNLEFLQSFFLSMFDLVPSRDKEALEDMNAVSCAIKSLYETLYPKAFSLLDL
KETLKRTSSNQLGLSLEPYLNNPLFNALNDAFNSNAFLNVINLDAITQNPKDLGLLAYYLFYKILEESRKNDSGFLVFLD
EFKSYVENDLLNTKINALITQARKANGVVVLALQDIYQLSGVKNAHSFLSNMGTLILYPQKNARELKHNFNVPLSETEIS
FLENTPLYARQVLVKNLGNGSSNMIDVSLESLGRYLKIFNSDSSHVNKVKALQKDYPTEWREKLLKS

Nucleotide


Download         Length: 2364 bp        

>NTDB_id=439528 HG583_RS00100 WP_202142978.1 14264..16627(+) (comB4) [Helicobacter pylori strain LIM-010]
ATGTTAGAAAAGCTTTTAGGCGCTATCAAACAAAAAGTTTCAAACTATTTTTTAGGGGTTTTGCCTAAAAGCTATTCTAT
GGGCGAAGAAAACAACATTTTAGGCTTGTATGATGAGCATTTTTTACTCACTAAAAACGAAAACTTAGTGGGTATTCTCC
GTTTAGAGGGGGTGAGTTACACCCATTTAAGCACAGAGCAATTGCAAGATCTTTTCACCGAGCGCCAGATGGCGTTGGAT
TCTTTGGAAAAAGTCGTGGCGCGCCTGGTGGTTAAAAGGCGTAAAATTGATTATAAACAAAGCATTCAATCTGATTCTCA
ATACTTGCAAGCGATTTTGAATCAGTTTGAAAATAAAGAAGTGCATGAAAATCAGTATTTTTTGGTTTTAGAAAGCGCGC
ACTCTTTACAGGGCGTTTTAGAGCATAAGAAAAAATCTTTCATGCACGCTAATAGGGAAAATTTTAAGGATATTCTCTCT
TATAAAGTGCATTTTTTGCAAGAAACTTTAAAAAGCCTAGAAATCCAGCTCAAAAATTATGCCCCCAAACTCTTAAGCTC
TAAAGAGGTTTTGAATTTTTATGCAGAATACATTAATGGGTTTGATCTCCCTTTAAAACCCCTAGTAGGGGGGTATTTGA
GCGATAGCTATATCGCTAGTTCCATCACTTTTGAAAAAGATTATTTCATTCAAGAAAGCTTTAATCAAAAAACCTATAAC
CGCTTGATTGGCATTAAAGCTTATGAGAGCGAGCGCATCACTTCTATAGCGGTGGGAGCGCTTTTATACCAAGAGACGCC
TTTGGATATTATCTTTTCCATAGAGCCTATGAGCACGCATAAAACGCTGAGTTTTTTAAAAGAGAGAGCCAAGTTTAGCA
TGTCCAATCTCGTTAAAAACGAGCTGCTAGAATACCAGGAATTAGTCAAAACCAAACGCCTATCCATGCAAAAATTCGCC
CTAAACGTTCTTATCAAAGCCCCCAGTTTAGAGGATTTAGACACTCAAACCAGCTTAATTTTAGGGCTTTTATTTAAAGA
AAACTTAGTGGGCGTTATAGAAACTTTTGGCTTGAAAGGAGGGTATTTTTCCTTTTTTCCTGAACGCATCCATTTAAACC
ACCGCTTGCGTTTTTTGACCTCTAAAGCCCTAGCGTGTTTAATGGTGTTTGAAAGGCAAAATTTAGGCTTTAAGGCTAAT
TCATGGGGGAATAGCCCTTTGAGCGTGTTTAAAAATTTGGATTATTCCCCTTTTTTATTCAATTTCCACAACCAAGAAGT
GAGCCACAATAACGCTAAAGAAATCGCCAGAGTGAATGGGCATACTTTAGTTATAGGGGCAACCGGAAGCGGTAAAAGCA
CGCTGATTAGCTTTTTAATGATGAGCGCTTTGAAATACCAAAACATGCGCCTTTTAGCTTTTGACAGGATGCATGGGCTG
TATTCTTTCACAAAATTTTTTAAAGGGCATTACCATGACGGCCAATCTTTTAGCATCAACCCCTTTTGTTTAGAGCCTAA
TTTGCAGAATTTAGAATTTTTGCAATCCTTCTTTTTGAGCATGTTTGATCTTGTCCCTTCAAGGGATAAAGAAGCCCTAG
AAGACATGAATGCGGTTTCTTGTGCGATTAAGAGCCTTTATGAGACTTTATACCCTAAAGCTTTTAGTTTGCTAGATCTT
AAAGAAACGCTTAAAAGAACCTCATCTAACCAATTGGGCTTGAGTTTAGAGCCGTATTTGAATAACCCCCTTTTTAACGC
TTTGAATGACGCGTTCAATTCCAACGCTTTTTTAAATGTGATAAACCTAGACGCTATCACCCAAAACCCCAAAGACTTAG
GGCTTTTAGCCTATTACTTGTTTTATAAAATTTTAGAAGAATCCAGGAAAAACGACAGCGGTTTTTTGGTTTTTTTAGAC
GAGTTTAAATCCTATGTGGAAAACGATTTGTTGAACACTAAAATCAACGCTTTAATCACGCAAGCCAGAAAAGCTAATGG
CGTGGTGGTGTTGGCCTTGCAAGATATTTACCAATTAAGCGGGGTTAAAAACGCTCATAGTTTTTTAAGCAACATGGGGA
CTCTCATTTTGTATCCGCAAAAAAACGCTAGGGAGTTGAAACACAACTTCAATGTGCCTTTGAGCGAGACTGAAATTTCT
TTTTTAGAAAACACCCCTTTGTATGCCAGGCAGGTTTTAGTCAAAAATCTGGGTAACGGAAGTTCTAACATGATTGATGT
GAGTTTGGAGAGTTTGGGGCGTTATTTGAAAATCTTCAATTCGGATTCCAGTCATGTGAACAAAGTGAAAGCGTTACAAA
AAGACTACCCTACAGAGTGGCGTGAGAAACTTTTGAAGAGCTAG

Domains

Predicted by InterproScan.

FtsK/SpoIIIE family (FtsK_SpoIIIE)

(426-466)

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(176-375)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

96.696

100

0.967