Detailed information
Bioinformatically predicted
Overview
| Name | clpC | Type | Regulator |
| Locus tag | HG420_RS05740 | Genome accession | NZ_CP051518 |
| Coordinates | 1120833..1123079 (+) | Length | 748 a.a. |
| NCBI ID | WP_015082116.1 | Uniprot ID | - |
| Organism | Lactococcus cremoris strain F | ||
| Function | degradation of ComX (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1122811..1161056 | 1120833..1123079 | flank | -268 |
Gene organization within MGE regions
Location: 1120833..1161056
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HG420_RS05740 (HG420_05750) | clpC | 1120833..1123079 (+) | 2247 | WP_015082116.1 | ATP-dependent Clp protease ATP-binding subunit | Regulator |
| HG420_RS05745 (HG420_05755) | - | 1123205..1123675 (-) | 471 | WP_015082117.1 | Rrf2 family transcriptional regulator | - |
| HG420_RS05750 (HG420_05760) | gap | 1123901..1124914 (+) | 1014 | Protein_1095 | type I glyceraldehyde-3-phosphate dehydrogenase | - |
| HG420_RS05755 (HG420_05765) | def | 1125138..1125773 (-) | 636 | WP_011675571.1 | peptide deformylase | - |
| HG420_RS05760 (HG420_05770) | - | 1125928..1126332 (+) | 405 | WP_015082118.1 | RNA pyrophosphohydrolase | - |
| HG420_RS05765 (HG420_05775) | uvrB | 1126394..1128472 (+) | 2079 | WP_011675573.1 | excinuclease ABC subunit UvrB | - |
| HG420_RS05770 (HG420_05780) | - | 1128654..1129130 (+) | 477 | WP_041931868.1 | transporter substrate-binding domain-containing protein | - |
| HG420_RS05780 (HG420_05790) | - | 1130597..1130962 (+) | 366 | WP_021213719.1 | transporter substrate-binding domain-containing protein | - |
| HG420_RS12300 | - | 1130977..1131516 (+) | 540 | WP_228763946.1 | M20/M25/M40 family metallo-hydrolase | - |
| HG420_RS12305 | - | 1131513..1131743 (+) | 231 | Protein_1103 | peptidase dimerization domain-containing protein | - |
| HG420_RS12310 | - | 1131962..1132096 (+) | 135 | WP_231097943.1 | hypothetical protein | - |
| HG420_RS05790 (HG420_05800) | fabZ | 1132148..1132603 (-) | 456 | WP_011675575.1 | 3-hydroxyacyl-ACP dehydratase FabZ | - |
| HG420_RS05795 (HG420_05805) | fabI | 1132878..1133630 (+) | 753 | WP_015082121.1 | enoyl-ACP reductase FabI | - |
| HG420_RS05800 (HG420_05810) | yidC | 1133816..1134778 (-) | 963 | WP_015082122.1 | membrane protein insertase YidC | - |
| HG420_RS05805 (HG420_05815) | - | 1134953..1135711 (-) | 759 | WP_011675578.1 | HAD-IIB family hydrolase | - |
| HG420_RS05810 (HG420_05820) | - | 1135806..1136396 (-) | 591 | WP_011675579.1 | ECF transporter S component | - |
| HG420_RS05815 (HG420_05825) | coaC | 1136413..1136949 (-) | 537 | WP_014573068.1 | phosphopantothenoylcysteine decarboxylase | - |
| HG420_RS05820 (HG420_05830) | - | 1136942..1137637 (-) | 696 | WP_011675580.1 | phosphopantothenate--cysteine ligase | - |
| HG420_RS05825 (HG420_05835) | - | 1137747..1137968 (-) | 222 | WP_015082124.1 | 2-hydroxymuconate tautomerase | - |
| HG420_RS05830 (HG420_05840) | - | 1138154..1140481 (+) | 2328 | Protein_1113 | cation-translocating P-type ATPase | - |
| HG420_RS05835 (HG420_05845) | - | 1140514..1140708 (+) | 195 | WP_051013160.1 | hypothetical protein | - |
| HG420_RS05840 (HG420_05850) | - | 1140729..1141840 (+) | 1112 | WP_127005270.1 | IS3-like element IS981 family transposase | - |
| HG420_RS05845 (HG420_05855) | - | 1142155..1142499 (+) | 345 | WP_014573064.1 | hypothetical protein | - |
| HG420_RS05850 (HG420_05860) | - | 1142577..1143359 (+) | 783 | WP_014573063.1 | hypothetical protein | - |
| HG420_RS05855 (HG420_05865) | - | 1143566..1143883 (+) | 318 | WP_014573062.1 | hypothetical protein | - |
| HG420_RS05860 (HG420_05870) | - | 1143883..1144905 (+) | 1023 | Protein_1119 | cell division protein FtsK | - |
| HG420_RS05870 (HG420_05880) | - | 1145076..1146119 (+) | 1044 | WP_011675590.1 | hypothetical protein | - |
| HG420_RS05875 (HG420_05885) | - | 1146125..1146334 (+) | 210 | WP_014573057.1 | hypothetical protein | - |
| HG420_RS05880 (HG420_05890) | - | 1146394..1147518 (+) | 1125 | WP_015082126.1 | site-specific integrase | - |
| HG420_RS05885 (HG420_05895) | - | 1147688..1148257 (+) | 570 | WP_011675593.1 | thymidine kinase | - |
| HG420_RS05890 (HG420_05900) | - | 1148268..1148711 (+) | 444 | WP_011675594.1 | hypothetical protein | - |
| HG420_RS05895 (HG420_05905) | prfA | 1148729..1149802 (+) | 1074 | WP_011675595.1 | peptide chain release factor 1 | - |
| HG420_RS05900 (HG420_05910) | - | 1149802..1150329 (+) | 528 | WP_015082127.1 | hypothetical protein | - |
| HG420_RS05905 (HG420_05915) | nfsA | 1150399..1151154 (+) | 756 | WP_011675598.1 | oxygen-insensitive NADPH nitroreductase | - |
| HG420_RS05910 (HG420_05920) | prmC | 1151259..1152074 (+) | 816 | WP_015082128.1 | peptide chain release factor N(5)-glutamine methyltransferase | - |
| HG420_RS05915 (HG420_05925) | - | 1152105..1152569 (+) | 465 | WP_011675600.1 | N-acetyltransferase | - |
| HG420_RS05920 (HG420_05930) | - | 1152887..1153486 (+) | 600 | WP_031288981.1 | L-threonylcarbamoyladenylate synthase | - |
| HG420_RS05925 (HG420_05935) | glyA | 1153719..1154966 (+) | 1248 | WP_015082129.1 | serine hydroxymethyltransferase | - |
| HG420_RS05930 (HG420_05940) | - | 1155147..1155749 (+) | 603 | WP_015082130.1 | lysozyme family protein | - |
| HG420_RS05935 (HG420_05945) | serC | 1155876..1156973 (+) | 1098 | WP_015082131.1 | 3-phosphoserine/phosphohydroxythreonine transaminase | - |
| HG420_RS05940 (HG420_05950) | - | 1156970..1158166 (+) | 1197 | WP_015082132.1 | 3-phosphoglycerate dehydrogenase family protein | - |
| HG420_RS05945 (HG420_05955) | serB | 1158212..1158874 (+) | 663 | WP_011675606.1 | phosphoserine phosphatase SerB | - |
| HG420_RS05950 (HG420_05960) | - | 1158917..1159204 (-) | 288 | Protein_1136 | acylphosphatase | - |
| HG420_RS05955 (HG420_05965) | - | 1159316..1160074 (+) | 759 | WP_168784113.1 | RNA methyltransferase | - |
| HG420_RS05960 (HG420_05970) | - | 1160286..1160675 (-) | 390 | WP_015082134.1 | cupin domain-containing protein | - |
| HG420_RS05965 (HG420_05975) | - | 1160675..1160902 (-) | 228 | WP_011675745.1 | hypothetical protein | - |
Sequence
Protein
Download Length: 748 a.a. Molecular weight: 83252.03 Da Isoelectric Point: 4.7362
>NTDB_id=439472 HG420_RS05740 WP_015082116.1 1120833..1123079(+) (clpC) [Lactococcus cremoris strain F]
MLCQNCNINEATIHLYTSVNGQKKQIDLCQNCYQIMKSGGQEALFGAGNASNGNSDEPFNPFNDIFSALQGQDFNGAASN
QTPPTQTGGRGPRGPQNPRAKQPKGMLEEFGINITESARRGEIDPVIGRDEEIKRVIEILNRRTKNNPVLIGEPGVGKTA
VVEGLAQKIVDDDVPQKLQNKEVIRLDVVSLVQGTGIRGQFEERMQKLMDEIRKRNDVIMFIDEIHEIVGAGSAGDGNMD
AGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVDETITILRGIQARYEDYHHVKYTDEAIEAAAH
LSNRYIQDRFLPDKAIDLLDESGSKKNLTLKFVDPEDINRRIADAESKKNEATKAEDFEKAAHFRDQISKLRELQKQEVT
DEDMPVITEKDIEQIVEQKTQIPVGDLKEKEQTQLINLADDLKAHVIGQDEAVDKISKAIRRSRVGLGKPNRPIGSFLFV
GPTGVGKTELAKQLAKELFGSSESMIRFDMSEYMEKHSVAKLIGAPPGYVGYEEAGQLTERVRRNPYSLILLDEIEKAHP
DVMHMFLQILEDGRLTDAQGRTVSFKDSLIIMTSNAGTGKVEASVGFGAAREGRTKSVLGQLGDFFSPEFMNRFDGIIEF
SALSKENLLKIVDLMLDEVNEQIGRNDIHLSVTQAAKEKLVDLGYNPAMGARPLRRTIQENIEDSIADFYIEHPEYKQLV
ADLIDDKIVISNQTQETAETTDEEVPAE
MLCQNCNINEATIHLYTSVNGQKKQIDLCQNCYQIMKSGGQEALFGAGNASNGNSDEPFNPFNDIFSALQGQDFNGAASN
QTPPTQTGGRGPRGPQNPRAKQPKGMLEEFGINITESARRGEIDPVIGRDEEIKRVIEILNRRTKNNPVLIGEPGVGKTA
VVEGLAQKIVDDDVPQKLQNKEVIRLDVVSLVQGTGIRGQFEERMQKLMDEIRKRNDVIMFIDEIHEIVGAGSAGDGNMD
AGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVDETITILRGIQARYEDYHHVKYTDEAIEAAAH
LSNRYIQDRFLPDKAIDLLDESGSKKNLTLKFVDPEDINRRIADAESKKNEATKAEDFEKAAHFRDQISKLRELQKQEVT
DEDMPVITEKDIEQIVEQKTQIPVGDLKEKEQTQLINLADDLKAHVIGQDEAVDKISKAIRRSRVGLGKPNRPIGSFLFV
GPTGVGKTELAKQLAKELFGSSESMIRFDMSEYMEKHSVAKLIGAPPGYVGYEEAGQLTERVRRNPYSLILLDEIEKAHP
DVMHMFLQILEDGRLTDAQGRTVSFKDSLIIMTSNAGTGKVEASVGFGAAREGRTKSVLGQLGDFFSPEFMNRFDGIIEF
SALSKENLLKIVDLMLDEVNEQIGRNDIHLSVTQAAKEKLVDLGYNPAMGARPLRRTIQENIEDSIADFYIEHPEYKQLV
ADLIDDKIVISNQTQETAETTDEEVPAE
Nucleotide
Download Length: 2247 bp
>NTDB_id=439472 HG420_RS05740 WP_015082116.1 1120833..1123079(+) (clpC) [Lactococcus cremoris strain F]
ATGCTTTGTCAAAATTGTAATATTAATGAAGCGACGATTCACCTTTACACAAGTGTAAATGGTCAGAAAAAACAAATTGA
TTTGTGCCAAAACTGTTATCAAATTATGAAATCTGGTGGTCAAGAAGCTTTATTTGGCGCAGGAAATGCCTCAAATGGAA
ATTCTGATGAACCCTTTAATCCGTTTAACGATATCTTCAGTGCTTTGCAAGGTCAAGATTTTAATGGGGCAGCAAGTAAT
CAAACTCCCCCAACACAAACGGGTGGGCGTGGTCCGCGTGGTCCACAAAATCCTCGGGCAAAACAACCTAAAGGGATGCT
AGAAGAATTCGGTATTAATATCACCGAATCAGCTCGTCGTGGCGAAATTGACCCAGTGATTGGGCGTGATGAAGAAATCA
AACGTGTTATTGAGATTTTAAATCGCAGAACTAAGAATAATCCAGTGCTAATTGGTGAACCTGGTGTTGGTAAAACAGCA
GTTGTTGAAGGTTTAGCACAAAAAATAGTCGATGACGATGTGCCACAAAAACTGCAAAATAAAGAAGTTATTCGTCTTGA
CGTGGTTTCTCTTGTTCAAGGAACAGGAATTCGTGGACAATTTGAAGAACGGATGCAAAAATTAATGGATGAAATCAGAA
AACGTAATGATGTCATTATGTTTATTGATGAAATTCATGAAATTGTCGGTGCTGGTTCTGCTGGCGACGGCAATATGGAT
GCAGGTAATATCCTAAAACCGGCTCTTGCACGTGGTGAGCTTCAATTGGTTGGAGCAACAACACTCAACGAATATCGTAT
TATTGAAAAAGATGCGGCACTTGAACGTCGGATGCAACCGGTCAAAGTAGATGAACCATCAGTTGATGAAACAATTACGA
TTTTGCGAGGCATTCAAGCACGTTATGAAGATTATCATCATGTGAAATACACTGATGAGGCTATTGAAGCAGCTGCTCAT
TTGTCAAATCGTTACATTCAAGACCGATTCTTACCAGATAAAGCCATCGACCTTTTAGATGAATCTGGTTCTAAGAAAAA
TCTGACTTTGAAATTTGTTGACCCTGAGGATATCAATCGTCGAATTGCTGATGCGGAAAGTAAGAAAAATGAAGCAACTA
AGGCTGAAGATTTTGAAAAAGCCGCTCATTTCCGTGACCAAATCAGTAAACTTCGTGAATTGCAAAAACAAGAAGTTACT
GACGAAGATATGCCAGTCATCACTGAAAAAGATATTGAACAAATTGTTGAACAAAAAACACAAATTCCAGTTGGGGATTT
GAAAGAAAAAGAACAAACTCAGTTGATTAATTTGGCTGATGATTTGAAAGCACATGTGATTGGTCAAGATGAAGCAGTAG
ATAAAATATCAAAAGCAATTCGTCGCTCACGTGTAGGTCTTGGCAAACCTAACCGTCCAATTGGTTCTTTCCTTTTTGTT
GGTCCAACAGGTGTAGGTAAAACCGAACTTGCTAAACAATTGGCTAAAGAATTATTTGGCTCAAGTGAGAGCATGATTCG
TTTTGATATGTCGGAATACATGGAAAAACATTCGGTGGCCAAATTGATTGGTGCGCCTCCAGGATATGTAGGTTATGAAG
AAGCGGGTCAATTGACCGAACGTGTTCGTCGTAATCCATACAGTTTGATTTTGCTTGATGAAATTGAAAAAGCTCATCCT
GATGTCATGCACATGTTCTTACAAATTCTTGAAGATGGCCGTCTGACAGATGCACAAGGACGGACAGTATCCTTCAAAGA
TAGTTTGATTATCATGACTTCAAATGCCGGAACTGGTAAAGTTGAAGCTTCTGTTGGATTTGGTGCAGCCCGCGAAGGAC
GAACTAAATCAGTGCTTGGTCAACTTGGTGATTTCTTTAGCCCTGAATTCATGAACCGTTTTGACGGAATTATTGAATTC
TCTGCTTTAAGCAAAGAAAATCTCCTTAAAATTGTTGATTTAATGCTTGATGAAGTCAATGAACAAATTGGACGTAATGA
TATTCATCTTAGTGTCACTCAAGCCGCTAAAGAAAAATTAGTGGACTTAGGATATAACCCTGCAATGGGTGCAAGACCTC
TTCGTAGAACAATTCAAGAAAATATTGAAGATTCAATTGCTGATTTCTACATTGAACATCCTGAATATAAACAATTGGTA
GCTGATTTGATTGATGATAAAATTGTCATTTCTAATCAAACCCAAGAAACAGCAGAAACCACTGATGAAGAAGTTCCTGC
CGAATAA
ATGCTTTGTCAAAATTGTAATATTAATGAAGCGACGATTCACCTTTACACAAGTGTAAATGGTCAGAAAAAACAAATTGA
TTTGTGCCAAAACTGTTATCAAATTATGAAATCTGGTGGTCAAGAAGCTTTATTTGGCGCAGGAAATGCCTCAAATGGAA
ATTCTGATGAACCCTTTAATCCGTTTAACGATATCTTCAGTGCTTTGCAAGGTCAAGATTTTAATGGGGCAGCAAGTAAT
CAAACTCCCCCAACACAAACGGGTGGGCGTGGTCCGCGTGGTCCACAAAATCCTCGGGCAAAACAACCTAAAGGGATGCT
AGAAGAATTCGGTATTAATATCACCGAATCAGCTCGTCGTGGCGAAATTGACCCAGTGATTGGGCGTGATGAAGAAATCA
AACGTGTTATTGAGATTTTAAATCGCAGAACTAAGAATAATCCAGTGCTAATTGGTGAACCTGGTGTTGGTAAAACAGCA
GTTGTTGAAGGTTTAGCACAAAAAATAGTCGATGACGATGTGCCACAAAAACTGCAAAATAAAGAAGTTATTCGTCTTGA
CGTGGTTTCTCTTGTTCAAGGAACAGGAATTCGTGGACAATTTGAAGAACGGATGCAAAAATTAATGGATGAAATCAGAA
AACGTAATGATGTCATTATGTTTATTGATGAAATTCATGAAATTGTCGGTGCTGGTTCTGCTGGCGACGGCAATATGGAT
GCAGGTAATATCCTAAAACCGGCTCTTGCACGTGGTGAGCTTCAATTGGTTGGAGCAACAACACTCAACGAATATCGTAT
TATTGAAAAAGATGCGGCACTTGAACGTCGGATGCAACCGGTCAAAGTAGATGAACCATCAGTTGATGAAACAATTACGA
TTTTGCGAGGCATTCAAGCACGTTATGAAGATTATCATCATGTGAAATACACTGATGAGGCTATTGAAGCAGCTGCTCAT
TTGTCAAATCGTTACATTCAAGACCGATTCTTACCAGATAAAGCCATCGACCTTTTAGATGAATCTGGTTCTAAGAAAAA
TCTGACTTTGAAATTTGTTGACCCTGAGGATATCAATCGTCGAATTGCTGATGCGGAAAGTAAGAAAAATGAAGCAACTA
AGGCTGAAGATTTTGAAAAAGCCGCTCATTTCCGTGACCAAATCAGTAAACTTCGTGAATTGCAAAAACAAGAAGTTACT
GACGAAGATATGCCAGTCATCACTGAAAAAGATATTGAACAAATTGTTGAACAAAAAACACAAATTCCAGTTGGGGATTT
GAAAGAAAAAGAACAAACTCAGTTGATTAATTTGGCTGATGATTTGAAAGCACATGTGATTGGTCAAGATGAAGCAGTAG
ATAAAATATCAAAAGCAATTCGTCGCTCACGTGTAGGTCTTGGCAAACCTAACCGTCCAATTGGTTCTTTCCTTTTTGTT
GGTCCAACAGGTGTAGGTAAAACCGAACTTGCTAAACAATTGGCTAAAGAATTATTTGGCTCAAGTGAGAGCATGATTCG
TTTTGATATGTCGGAATACATGGAAAAACATTCGGTGGCCAAATTGATTGGTGCGCCTCCAGGATATGTAGGTTATGAAG
AAGCGGGTCAATTGACCGAACGTGTTCGTCGTAATCCATACAGTTTGATTTTGCTTGATGAAATTGAAAAAGCTCATCCT
GATGTCATGCACATGTTCTTACAAATTCTTGAAGATGGCCGTCTGACAGATGCACAAGGACGGACAGTATCCTTCAAAGA
TAGTTTGATTATCATGACTTCAAATGCCGGAACTGGTAAAGTTGAAGCTTCTGTTGGATTTGGTGCAGCCCGCGAAGGAC
GAACTAAATCAGTGCTTGGTCAACTTGGTGATTTCTTTAGCCCTGAATTCATGAACCGTTTTGACGGAATTATTGAATTC
TCTGCTTTAAGCAAAGAAAATCTCCTTAAAATTGTTGATTTAATGCTTGATGAAGTCAATGAACAAATTGGACGTAATGA
TATTCATCTTAGTGTCACTCAAGCCGCTAAAGAAAAATTAGTGGACTTAGGATATAACCCTGCAATGGGTGCAAGACCTC
TTCGTAGAACAATTCAAGAAAATATTGAAGATTCAATTGCTGATTTCTACATTGAACATCCTGAATATAAACAATTGGTA
GCTGATTTGATTGATGATAAAATTGTCATTTCTAATCAAACCCAAGAAACAGCAGAAACCACTGATGAAGAAGTTCCTGC
CGAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| clpC | Lactococcus lactis subsp. cremoris KW2 |
99.733 |
100 |
0.997 |
| clpE | Streptococcus mutans UA159 |
75.762 |
100 |
0.765 |
| clpE | Streptococcus pneumoniae Rx1 |
75.679 |
98.396 |
0.745 |
| clpE | Streptococcus pneumoniae D39 |
75.679 |
98.396 |
0.745 |
| clpE | Streptococcus pneumoniae R6 |
75.679 |
98.396 |
0.745 |
| clpE | Streptococcus pneumoniae TIGR4 |
75.679 |
98.396 |
0.745 |
| clpC | Bacillus subtilis subsp. subtilis str. 168 |
48.664 |
95.053 |
0.463 |
| clpC | Lactococcus lactis subsp. lactis strain DGCC12653 |
46.87 |
87.567 |
0.41 |
| clpC | Streptococcus pneumoniae Rx1 |
46.795 |
83.422 |
0.39 |
| clpC | Streptococcus pneumoniae D39 |
46.795 |
83.422 |
0.39 |
| clpC | Streptococcus pneumoniae TIGR4 |
46.795 |
83.422 |
0.39 |
| clpC | Streptococcus thermophilus LMD-9 |
46.266 |
82.353 |
0.381 |
| clpC | Streptococcus thermophilus LMG 18311 |
46.104 |
82.353 |
0.38 |
| clpC | Streptococcus mutans UA159 |
45.631 |
82.62 |
0.377 |