Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   HG561_RS02745 Genome accession   NZ_CP051506
Coordinates   554271..556055 (-) Length   594 a.a.
NCBI ID   WP_202168746.1    Uniprot ID   -
Organism   Helicobacter pylori strain SHIM-007     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 549271..561055
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HG561_RS02715 (HG561_02705) - 549862..550110 (+) 249 WP_000790556.1 RNA-binding protein -
  HG561_RS02720 (HG561_02710) - 550313..551134 (-) 822 WP_202168744.1 glycosyltransferase family 25 protein -
  HG561_RS02725 (HG561_02715) trxB 551301..552236 (-) 936 WP_000564369.1 thioredoxin-disulfide reductase -
  HG561_RS02730 (HG561_02720) trxA 552242..552562 (-) 321 WP_000020191.1 thioredoxin -
  HG561_RS02735 (HG561_02725) - 552651..552995 (-) 345 WP_001211672.1 YraN family protein -
  HG561_RS02740 (HG561_02730) - 552995..554260 (-) 1266 WP_202168745.1 homoserine dehydrogenase -
  HG561_RS02745 (HG561_02735) uvrC 554271..556055 (-) 1785 WP_202168746.1 excinuclease ABC subunit UvrC Machinery gene
  HG561_RS02750 (HG561_02740) - 556056..556517 (-) 462 WP_202168747.1 hypothetical protein -
  HG561_RS02755 (HG561_02745) - 556509..556688 (+) 180 WP_000468794.1 hypothetical protein -
  HG561_RS02760 (HG561_02750) - 556700..557341 (-) 642 WP_202168748.1 ATP-binding cassette domain-containing protein -
  HG561_RS02765 (HG561_02755) - 557345..559006 (-) 1662 WP_202168749.1 ABC transporter permease/substrate-binding protein -
  HG561_RS02770 (HG561_02760) - 559186..559623 (-) 438 WP_001031795.1 hypothetical protein -
  HG561_RS02775 (HG561_02765) motB 559627..560394 (-) 768 WP_202136051.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68924.26 Da        Isoelectric Point: 9.7378

>NTDB_id=439313 HG561_RS02745 WP_202168746.1 554271..556055(-) (uvrC) [Helicobacter pylori strain SHIM-007]
MADLLSSLKNLSHSSGVYQYFDKNHQLLYIGKAKNLKKRIKSYFSVRNNEITPNYRTSLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGKGNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQEFISHRYSKKIALSIPKKGDKLALIEIAMRNAQEIFSQEKTSNEDLILEEARSLFKLECMPYRVEIFDT
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRVQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GESSVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=439313 HG561_RS02745 WP_202168746.1 554271..556055(-) (uvrC) [Helicobacter pylori strain SHIM-007]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGACAAAAACCACCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAACGCATCAAAAGCTATTTTTCTGTCCGTAATAATGAAATCACGCCCA
ATTATCGCACCAGCTTACGCATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCTAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATGGCAAGGGTAATAAGGCGGT
GTTGGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCAGAACAGATTTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCTCACCGATACTCTAAAAAAATCGCTCTTAGTATTCC
TAAAAAAGGCGATAAACTCGCTTTAATAGAAATCGCTATGAGAAACGCTCAAGAGATTTTTAGCCAGGAAAAAACCTCTA
ATGAGGATCTGATTTTAGAAGAAGCGCGATCGCTCTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTGCCAAAGAGC
CGCCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGTGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGAGGCGCTAAAGACATTAT
CCATACGCCTAGCGATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAATCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCTGTTTTAAAAAAACGAATTTAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.801

100

0.968