Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   HG563_RS02735 Genome accession   NZ_CP051504
Coordinates   564827..566611 (-) Length   594 a.a.
NCBI ID   WP_202273592.1    Uniprot ID   -
Organism   Helicobacter pylori strain SHIM-011     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 559827..571611
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HG563_RS02705 (HG563_02705) - 560417..560665 (+) 249 WP_000790556.1 RNA-binding protein -
  HG563_RS02710 (HG563_02710) - 560870..561691 (-) 822 WP_001263418.1 glycosyltransferase family 25 protein -
  HG563_RS02715 (HG563_02715) trxB 561857..562792 (-) 936 WP_000564373.1 thioredoxin-disulfide reductase -
  HG563_RS02720 (HG563_02720) trxA 562798..563118 (-) 321 WP_000020204.1 thioredoxin -
  HG563_RS02725 (HG563_02725) - 563207..563551 (-) 345 WP_001211675.1 YraN family protein -
  HG563_RS02730 (HG563_02730) - 563551..564816 (-) 1266 WP_202273591.1 homoserine dehydrogenase -
  HG563_RS02735 (HG563_02735) uvrC 564827..566611 (-) 1785 WP_202273592.1 excinuclease ABC subunit UvrC Machinery gene
  HG563_RS02740 (HG563_02740) - 566612..567073 (-) 462 WP_000437184.1 hypothetical protein -
  HG563_RS02745 (HG563_02745) - 567065..567244 (+) 180 WP_000468794.1 hypothetical protein -
  HG563_RS02750 (HG563_02750) - 567256..567897 (-) 642 WP_202273593.1 ATP-binding cassette domain-containing protein -
  HG563_RS02755 (HG563_02755) - 567899..569560 (-) 1662 WP_202273594.1 ABC transporter permease/substrate-binding protein -
  HG563_RS02760 (HG563_02760) - 569740..570177 (-) 438 WP_001031795.1 hypothetical protein -
  HG563_RS02765 (HG563_02765) motB 570181..570948 (-) 768 WP_001085304.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68778.07 Da        Isoelectric Point: 9.6115

>NTDB_id=439269 HG563_RS02735 WP_202273592.1 564827..566611(-) (uvrC) [Helicobacter pylori strain SHIM-011]
MADLLSSLKNLSHSSGVYQYFDKNHQLLYIGKAKNLKKRIKSYFSIHNNEITPNYRTSLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGKGNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKISNEDLILEEAQSLFKLECMPYRVEIFDT
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTASDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKIKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQERNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=439269 HG563_RS02735 WP_202273592.1 564827..566611(-) (uvrC) [Helicobacter pylori strain SHIM-011]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGACAAAAACCACCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTATCCACAATAATGAAATCACGCCCA
ATTATCGCACCAGCTTACGCATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCTAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGGCCTTTTACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAGTAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGATAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATGGCAAGGGTAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTTAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCAGAACAGATTTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCTCACCAATACTCTAAAAAAATCGCTCTTAGTATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAGGAAAAAATCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCAATCGCTCTTTAAATTAGAGTGCATGCCTTATAGAGTGGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGTTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCCAAAGAGC
CGCCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGAGGCGCTAAAGACATTAT
CCACACCGCTAGCGATACTTTTAAATTGCTCCCTAGCGACAAGCGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAAATTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAACAAGAAAGAAA
CGCCGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(384-538)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.465

100

0.965