Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   HG565_RS03100 Genome accession   NZ_CP051502
Coordinates   647281..649065 (-) Length   594 a.a.
NCBI ID   WP_202169881.1    Uniprot ID   -
Organism   Helicobacter pylori strain PUNO-001     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 642281..654065
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HG565_RS03070 (HG565_03060) - 642871..643119 (+) 249 WP_000790556.1 RNA-binding protein -
  HG565_RS03075 (HG565_03065) - 643322..644143 (-) 822 WP_202169879.1 glycosyltransferase family 25 protein -
  HG565_RS03080 (HG565_03070) trxB 644311..645246 (-) 936 WP_000564369.1 thioredoxin-disulfide reductase -
  HG565_RS03085 (HG565_03075) trxA 645252..645572 (-) 321 WP_000020200.1 thioredoxin -
  HG565_RS03090 (HG565_03080) - 645661..646005 (-) 345 WP_001211686.1 YraN family protein -
  HG565_RS03095 (HG565_03085) - 646005..647270 (-) 1266 WP_202169880.1 homoserine dehydrogenase -
  HG565_RS03100 (HG565_03090) uvrC 647281..649065 (-) 1785 WP_202169881.1 excinuclease ABC subunit UvrC Machinery gene
  HG565_RS03105 (HG565_03095) - 649066..649527 (-) 462 WP_202169882.1 hypothetical protein -
  HG565_RS03110 (HG565_03100) - 649519..649698 (+) 180 WP_000468794.1 hypothetical protein -
  HG565_RS03115 (HG565_03105) - 649710..650351 (-) 642 WP_202169883.1 ATP-binding cassette domain-containing protein -
  HG565_RS03120 (HG565_03110) - 650353..652014 (-) 1662 WP_202169884.1 ABC transporter permease/substrate-binding protein -
  HG565_RS03125 (HG565_03115) - 652194..652643 (-) 450 WP_001031786.1 hypothetical protein -
  HG565_RS03130 (HG565_03120) motB 652647..653414 (-) 768 WP_202169885.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68837.15 Da        Isoelectric Point: 9.7378

>NTDB_id=439227 HG565_RS03100 WP_202169881.1 647281..649065(-) (uvrC) [Helicobacter pylori strain PUNO-001]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSVHNNEITPNYRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGKGHKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQEFISHRYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFKLECMPYRVEIFDT
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFAKESPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTASDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLREKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=439227 HG565_RS03100 WP_202169881.1 647281..649065(-) (uvrC) [Helicobacter pylori strain PUNO-001]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGACAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTGTCCACAATAATGAAATCACGCCCA
ATTATCGCGCCAGCTTACGCATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTGATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATCTATAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATGGCAAGGGCCATAAGGCGGT
GTTGGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTTAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTAATGCCTGAACAGATTTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCTCACCGATACTCTAAAAAAATCGCTCTTAGTATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAGGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTTACCAGAAGGGCTTTAGATTTTGCCAAAGAGT
CGCCGCCTAATTTATGGGTGATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGAGGCGCTAAAGACATTAT
CCACACCGCTAGCGATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAGAGAAAAGGGCATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATTTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.801

100

0.968