Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   HG568_RS02575 Genome accession   NZ_CP051499
Coordinates   530565..532349 (-) Length   594 a.a.
NCBI ID   WP_202167913.1    Uniprot ID   -
Organism   Helicobacter pylori strain PUNO-004     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 525565..537349
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HG568_RS02545 (HG568_02545) - 526154..526402 (+) 249 WP_000790556.1 RNA-binding protein -
  HG568_RS02550 (HG568_02550) - 526606..527427 (-) 822 WP_202167911.1 glycosyltransferase family 25 protein -
  HG568_RS02555 (HG568_02555) trxB 527594..528529 (-) 936 WP_202167912.1 thioredoxin-disulfide reductase -
  HG568_RS02560 (HG568_02560) trxA 528535..528855 (-) 321 WP_000020199.1 thioredoxin -
  HG568_RS02565 (HG568_02565) - 528944..529288 (-) 345 WP_001211675.1 YraN family protein -
  HG568_RS02570 (HG568_02570) - 529289..530554 (-) 1266 WP_154443338.1 homoserine dehydrogenase -
  HG568_RS02575 (HG568_02575) uvrC 530565..532349 (-) 1785 WP_202167913.1 excinuclease ABC subunit UvrC Machinery gene
  HG568_RS02580 (HG568_02580) - 532350..532811 (-) 462 WP_202167914.1 hypothetical protein -
  HG568_RS02585 (HG568_02585) - 532803..532982 (+) 180 WP_000468798.1 hypothetical protein -
  HG568_RS02590 (HG568_02590) - 532985..533635 (-) 651 WP_202167915.1 ATP-binding cassette domain-containing protein -
  HG568_RS02595 (HG568_02595) - 533639..535300 (-) 1662 WP_202167916.1 glycine betaine ABC transporter substrate-binding protein -
  HG568_RS02600 (HG568_02600) - 535483..535920 (-) 438 WP_202167917.1 hypothetical protein -
  HG568_RS02605 (HG568_02605) motB 535924..536691 (-) 768 WP_001085315.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68827.19 Da        Isoelectric Point: 9.6980

>NTDB_id=439162 HG568_RS02575 WP_202167913.1 530565..532349(-) (uvrC) [Helicobacter pylori strain PUNO-004]
MADLLSSLKNLSNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNYRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGKGHKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEVQSLFKLECMPYRVEIFDV
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTASDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLREKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=439162 HG568_RS02575 WP_202167913.1 530565..532349(-) (uvrC) [Helicobacter pylori strain PUNO-004]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTAACAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTACATCGGTAAAGCGAAAAACTTAAAAAAGCGCATCAAAAGCTATTTTTCCATCCGTAATAATGAAATCACGCCCA
ATTATCGCGCAAGCTTACGCATCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTAGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTGATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAAGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAAGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAGAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTACGATTTGGATATTTTTGCTTTTTATGGCAAGGGCCATAAGGCGGT
GTTGGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAACCATTACCAATCGCATTTGCCTTTAATGCCAGAACAGATTTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCCCACCAATACTCTAAAAAAATCGCTCTTAGTATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAGGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGTGCAATCGCTCTTCAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGATGTA
AGCCACCATGCCAACAGTCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCCAAAGAGC
CGCCGCCTAATTTGTGGGTGATTGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCACACCGCTAGCGATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAGAGAAAAGGGCATA
GGAGAAGCCAGTGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAAGAAAAAAA
CGCCGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(384-538)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

97.138

100

0.971