Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   HG569_RS02585 Genome accession   NZ_CP051498
Coordinates   528351..530135 (-) Length   594 a.a.
NCBI ID   WP_202272982.1    Uniprot ID   -
Organism   Helicobacter pylori strain PUNO-006     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 523351..535135
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HG569_RS02555 (HG569_02555) - 523941..524189 (+) 249 WP_078245806.1 RNA-binding protein -
  HG569_RS02560 (HG569_02560) - 524394..525215 (-) 822 WP_202272980.1 glycosyltransferase family 25 protein -
  HG569_RS02565 (HG569_02565) trxB 525380..526315 (-) 936 WP_180587395.1 thioredoxin-disulfide reductase -
  HG569_RS02570 (HG569_02570) trxA 526321..526641 (-) 321 WP_000020200.1 thioredoxin -
  HG569_RS02575 (HG569_02575) - 526730..527074 (-) 345 WP_001211689.1 YraN family protein -
  HG569_RS02580 (HG569_02580) - 527075..528340 (-) 1266 WP_202272981.1 homoserine dehydrogenase -
  HG569_RS02585 (HG569_02585) uvrC 528351..530135 (-) 1785 WP_202272982.1 excinuclease ABC subunit UvrC Machinery gene
  HG569_RS02590 (HG569_02590) - 530136..530597 (-) 462 WP_202272983.1 hypothetical protein -
  HG569_RS02595 (HG569_02595) - 530589..530768 (+) 180 WP_000468794.1 hypothetical protein -
  HG569_RS02600 (HG569_02600) - 530780..531421 (-) 642 WP_202272984.1 ABC transporter ATP-binding protein -
  HG569_RS02605 (HG569_02605) - 531425..533086 (-) 1662 WP_202272985.1 ABC transporter permease/substrate-binding protein -
  HG569_RS02610 (HG569_02610) - 533264..533713 (-) 450 WP_202272986.1 hypothetical protein -
  HG569_RS02615 (HG569_02615) motB 533717..534484 (-) 768 WP_001085315.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68675.94 Da        Isoelectric Point: 9.7409

>NTDB_id=439142 HG569_RS02585 WP_202272982.1 528351..530135(-) (uvrC) [Helicobacter pylori strain PUNO-006]
MADLLSSLKNLPNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIHNNEITPNPRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGGNNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLS
ACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDRILEEARSLFNLECMPYRVEIFDT
SHHSNSQCVGGMVVYENNAFQKNSYRRYHLKGSNEYAQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEVLKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIYTINNTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=439142 HG569_RS02585 WP_202272982.1 528351..530135(-) (uvrC) [Helicobacter pylori strain PUNO-006]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTCCTAACAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTACATTGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTATCCACAATAATGAAATCACGCCCA
ATCCTCGTGCAAGCTTACGCATCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTGGAAAATTCTTTAATCAAGCAGCTCAAGCCTAAATACAACATTCTTTTAAGAGATGATAAAACTTA
CCCTTATATTTACATGGATTTTTCTACTGATTTCCCTATCCCTTTAATCACACGAAAAATCTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTGGACAGCTTGTATGAGTTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTAATTTATAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTTTACGATTTGGATATTTTTGCTTTTTATGGTGGGAACAATAAAGCGGT
GTTGGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTTAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAACCATTACCAATCGCATTTGCCTTTGATGCCTGAACAGATCTTATTGAGC
GCTTGTTCTAATGAAACGCTTAAAGAATTGCAAGAGTTTATCTCCCATCAATATTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAGGGCGATAAACTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCGGATTTTAGAAGAAGCGCGATCGCTTTTCAATTTAGAATGCATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATTCAAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACAATGCATTCCAAAAAAACTCTTATCGGCG
CTACCATTTAAAAGGCTCTAACGAATACGCTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCTAAAGAGC
CGCCACCTAATTTGTGGGTGATTGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAGTTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAGGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CTATACGATTAATAATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGCATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTGTTAAAAAAACGAATTTAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

97.138

100

0.971