Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   HG572_RS03870 Genome accession   NZ_CP051495
Coordinates   830724..832508 (+) Length   594 a.a.
NCBI ID   WP_202139263.1    Uniprot ID   -
Organism   Helicobacter pylori strain PUNO-009     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 825724..837508
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HG572_RS03840 (HG572_03835) motB 826488..827261 (+) 774 WP_187849914.1 flagellar motor protein MotB -
  HG572_RS03845 (HG572_03840) - 827267..827704 (+) 438 WP_001875392.1 hypothetical protein -
  HG572_RS03850 (HG572_03845) - 827773..829434 (+) 1662 WP_202139262.1 glycine betaine ABC transporter substrate-binding protein -
  HG572_RS03855 (HG572_03850) - 829438..830088 (+) 651 WP_202137604.1 ATP-binding cassette domain-containing protein -
  HG572_RS03860 (HG572_03855) - 830091..830270 (-) 180 WP_000468793.1 hypothetical protein -
  HG572_RS03865 (HG572_03860) - 830262..830723 (+) 462 WP_001960675.1 hypothetical protein -
  HG572_RS03870 (HG572_03865) uvrC 830724..832508 (+) 1785 WP_202139263.1 excinuclease ABC subunit UvrC Machinery gene
  HG572_RS03875 (HG572_03870) - 832519..833784 (+) 1266 WP_202139264.1 homoserine dehydrogenase -
  HG572_RS03880 (HG572_03875) - 833785..834129 (+) 345 WP_202139265.1 YraN family protein -
  HG572_RS03885 (HG572_03880) trxA 834218..834538 (+) 321 WP_000020208.1 thioredoxin -
  HG572_RS03890 (HG572_03885) trxB 834543..835478 (+) 936 WP_202139266.1 thioredoxin-disulfide reductase -
  HG572_RS03895 (HG572_03890) - 835646..836467 (+) 822 WP_202139267.1 glycosyltransferase family 25 protein -
  HG572_RS03900 (HG572_03895) - 836666..836914 (-) 249 WP_000790556.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68642.86 Da        Isoelectric Point: 9.7039

>NTDB_id=439080 HG572_RS03870 WP_202139263.1 830724..832508(+) (uvrC) [Helicobacter pylori strain PUNO-009]
MADLLSSLKNLSSSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNHRASLRVQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEDKITKEEYLKIAKECLEMIENKDRLIKELELKMERLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGGNNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLS
ACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFNLECMPYRVEIFDT
SHHSNSQCVGGMVVYENNAFQKNSYRRYHLKGSNEYAQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEVLKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIYTINNTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=439080 HG572_RS03870 WP_202139263.1 830724..832508(+) (uvrC) [Helicobacter pylori strain PUNO-009]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTAGTAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTACATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTATCCGTAACAATGAAATCACGCCCA
ACCATCGCGCAAGCTTACGCGTCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTGATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTATATGGATTTTTCCACTGACTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACAAGCGGGGCTAAGGATATTTTGGATAGCTTGTATGAATTGCTCCCGTTGGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGGATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAGGCTCATCAAAGAGCTTGAATTGA
AAATGGAGCGCCTTTCTAGTAACTTGCGTTTTGAAGAAGCCCTAATTTATAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTACGATTTGGATATTTTTGCTTTTTATGGTGGGAACAACAAGGCGGT
GTTAGTGAAAATGTTCATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCCCTTAATGGGTTTGACA
CCGATGAGGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCTGAACAGATCTTATTGAGC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAGTTTATCTCTCATCAATATTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAGGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTCAATTTAGAATGCATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATTCAAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATAACGCCTTCCAAAAAAACTCTTATCGGCG
TTACCATTTAAAAGGCTCTAACGAATACGCTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCTAAAGAGC
CACCGCCTAATTTGTGGGTGATTGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAGTTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAGGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CTATACGATTAATAATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAATGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGCATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATTTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.97

100

0.97