Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   HG579_RS04300 Genome accession   NZ_CP051493
Coordinates   918614..920398 (+) Length   594 a.a.
NCBI ID   WP_202133460.1    Uniprot ID   -
Organism   Helicobacter pylori strain LIM-006     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 913614..925398
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HG579_RS04270 (HG579_04260) motB 914379..915152 (+) 774 WP_202133457.1 flagellar motor protein MotB -
  HG579_RS04275 (HG579_04265) - 915158..915595 (+) 438 WP_001875641.1 hypothetical protein -
  HG579_RS04280 (HG579_04270) - 915664..917325 (+) 1662 WP_202133458.1 ABC transporter permease/substrate-binding protein -
  HG579_RS04285 (HG579_04275) - 917328..917969 (+) 642 WP_202133459.1 ATP-binding cassette domain-containing protein -
  HG579_RS04290 (HG579_04280) - 917981..918160 (-) 180 WP_000468793.1 hypothetical protein -
  HG579_RS04295 (HG579_04285) - 918152..918613 (+) 462 WP_000437179.1 hypothetical protein -
  HG579_RS04300 (HG579_04290) uvrC 918614..920398 (+) 1785 WP_202133460.1 excinuclease ABC subunit UvrC Machinery gene
  HG579_RS04305 (HG579_04295) - 920409..921674 (+) 1266 WP_202133461.1 homoserine dehydrogenase -
  HG579_RS04310 (HG579_04300) - 921675..922019 (+) 345 WP_001974044.1 YraN family protein -
  HG579_RS04315 (HG579_04305) trxA 922108..922428 (+) 321 WP_000020210.1 thioredoxin -
  HG579_RS04320 (HG579_04310) trxB 922434..923369 (+) 936 WP_108346516.1 thioredoxin-disulfide reductase -
  HG579_RS04325 (HG579_04315) - 923726..924547 (+) 822 WP_202133462.1 glycosyltransferase family 25 protein -
  HG579_RS04330 (HG579_04320) - 924769..925017 (-) 249 WP_000790557.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68531.90 Da        Isoelectric Point: 9.7487

>NTDB_id=439031 HG579_RS04300 WP_202133460.1 918614..920398(+) (uvrC) [Helicobacter pylori strain LIM-006]
MADLLSSLKNLPNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNPRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEDKITKEEYLKIAKKCLEMIENKDKLIKELELKMECLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGASNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLS
ACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFKLECMPYRVEIFDT
SHHANSQCVGGMVVYENNAFQKNSYRRYHLKGSDEYAQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSNTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASDQEKNAVLRKRK

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=439031 HG579_RS04300 WP_202133460.1 918614..920398(+) (uvrC) [Helicobacter pylori strain LIM-006]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTCCTAATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAAGCGAAAAACTTAAAAAAGCGCATCAAAAGCTATTTTTCCATCCGTAATAATGAAATCACGCCCA
ATCCTCGTGCAAGCTTACGCATCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTGGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACCTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTGGACAGCTTGTATGAGTTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGTGAGGATAAAATCACTAA
AGAAGAATATTTAAAAATCGCTAAAAAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTGA
AAATGGAGTGCCTTTCTAGTAACTTGCGTTTTGAAGAAGCCCTAATTTACAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTACGATTTGGATATTTTTGCTTTTTATGGTGCAAGCAATAAGGCGGT
GTTGGTGAAAATGTTTATGCGCGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAACGGATTTGACA
CCGATGAAGCGATGAAACAAGCCATTATCAACCATTACCAATCGCATTTGCCTTTGATGCCTGAACAGATCTTATTGAGT
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAGTTTATCTCTCATCAATATTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAGGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTCAAATTAGAATGTATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACAATGCCTTTCAAAAAAACTCTTATCGGCG
CTACCATTTGAAAGGCTCTGATGAATACGCTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCCAAAGAGC
CACCGCCTAATTTGTGGGTGATTGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCATACGCCCAGCAATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCACAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGCATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGATCAGGAAAAAAA
CGCCGTGTTAAGAAAACGAAAATAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

97.639

99.832

0.975