Detailed information NTG0438920

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: HGO96_RS06485
• Genome accession: NZ_CP051484
• Coordinates: 1309770..1310813 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain NGA71
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1304770..1315813

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HGO96_RS06455 (HGO96_09725)	-	1305194..1306450 (-)	1257	WP_077446664.1	aminopeptidase	-
HGO96_RS06460 (HGO96_09730)	-	1306453..1306653 (-)	201	WP_000180460.1	DUF1128 family protein	-
HGO96_RS06465 (HGO96_09735)	-	1306800..1307264 (+)	465	WP_054189636.1	low molecular weight protein-tyrosine-phosphatase	-
HGO96_RS06470 (HGO96_09740)	-	1307271..1307546 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
HGO96_RS06475 (HGO96_09745)	-	1307824..1309041 (+)	1218	WP_000037088.1	YihY/virulence factor BrkB family protein	-
HGO96_RS06480 (HGO96_09750)	vraR	1309151..1309780 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
HGO96_RS06485 (HGO96_09755)	vraS	1309770..1310813 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
HGO96_RS06490 (HGO96_09760)	liaF	1310810..1311511 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
HGO96_RS06495 (HGO96_09765)	-	1311526..1311912 (-)	387	WP_001110179.1	hypothetical protein	-
HGO96_RS06500 (HGO96_09770)	map	1312129..1312887 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
HGO96_RS06505 (HGO96_09775)	-	1313647..1314633 (+)	987	WP_054189634.1	aromatic acid exporter family protein	-
HGO96_RS06510 (HGO96_09780)	-	1315142..1315555 (-)	414	WP_077446671.1	hypothetical protein	-
HGO96_RS06515 (HGO96_09785)	-	1315584..1315694 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=438920 HGO96_RS06485 WP_001017131.1 1309770..1310813(-) (vraS) [Staphylococcus aureus strain NGA71]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=438920 HGO96_RS06485 WP_001017131.1 1309770..1310813(-) (vraS) [Staphylococcus aureus strain NGA71]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTTATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACGGTTGGTATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAACGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACAAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTCCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCACTTGGTTTAAAAG
ACAAATCATTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1