Detailed information NTG0438846

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: HGO93_RS10770
• Genome accession: NZ_CP051482
• Coordinates: 2198233..2199120 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain NGA104a
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2193233..2204120

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HGO93_RS10740 (HGO93_13695)	-	2193965..2194726 (+)	762	WP_000323441.1	alpha/beta hydrolase family protein	-
HGO93_RS10745 (HGO93_13690)	-	2194971..2195426 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
HGO93_RS10750	-	2195548..2195649 (+)	102	WP_000731972.1	SE2200 family small protein	-
HGO93_RS10755 (HGO93_13680)	-	2195709..2197133 (-)	1425	WP_000953748.1	alkaline phosphatase	-
HGO93_RS10760 (HGO93_13675)	-	2197331..2197531 (+)	201	WP_000604727.1	hypothetical protein	-
HGO93_RS10765 (HGO93_13670)	braR	2197557..2198222 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
HGO93_RS10770 (HGO93_13665)	braS	2198233..2199120 (+)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
HGO93_RS10775 (HGO93_13660)	-	2199228..2199983 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
HGO93_RS10780 (HGO93_13655)	-	2199980..2201980 (+)	2001	WP_000776740.1	ABC transporter permease	-
HGO93_RS10785 (HGO93_13650)	-	2202639..2202752 (+)	114	Protein_2092	hypothetical protein	-
HGO93_RS10790 (HGO93_13645)	-	2203134..2203394 (+)	261	WP_001791974.1	hypothetical protein	-
HGO93_RS10795 (HGO93_13640)	-	2203404..2203901 (+)	498	WP_001065268.1	glutathione peroxidase	-
HGO93_RS10800 (HGO93_13635)	-	2204009..2204101 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=438846 HGO93_RS10770 WP_000143417.1 2198233..2199120(+) (braS) [Staphylococcus aureus strain NGA104a]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=438846 HGO93_RS10770 WP_000143417.1 2198233..2199120(+) (braS) [Staphylococcus aureus strain NGA104a]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99